Rv3443c

Tuberculist information
Gene namerplM
Protein function50S ribosomal protein L13 RplM
Functional category(tuberculist)information pathways
Gene location(kb)3861.95
Molecular mass(da)16304.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 147
	  		  	1    VPTYAPKAGDTTRSWYVIDATDVVLGRLAVAAANLLRGKHKPTFAPNVDGGDFVIVINAD   60
			  	61   KVAISGDKLQHKMVYRHSGYPGGLHKRTIGELMQRHPDRVVEKAILGMLPKNRLSRQIQR  120
			  	121  KLRVYAGPEHPHSAQQPVPYELKQVAQ

Known structures in the PDB
No Known structures
1 15 29 43 57 71 85 99 113 127 141 Range: 15 to 142  |  Coverage: 86% Ribosomal_L13 Range: 1 to 137  |  Coverage: 92% 1 Range: 1 to 147  |  Coverage: 99% 1
Number of amino acids : 147
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L13PF0057215-142
Mtb Structural Proteome models
Model Number1
Model nameRv3443c
Template2AW4    JPDBCREDO
Template coverage1_137
Template Identity(%)52.6
Model coverage(%)92.5
Normalized DOPE score1.032

Structure Models from Chopin
Model Number1
Profilec.21.1.1 - 3.90.1180.10
Click for model details
zscore33.4
Residue begin1
Residue end147
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3443cGene nameConfidence Score
Rv0719rplF0.999
Rv3442crpsI0.999
Rv0702rplD0.999
Rv2890crpsB0.998
Rv0714rplN0.998
Rv0701rplC0.998
Rv0641rplA0.998
Rv0716rplE0.998
Rv0716rplE0.998
Rv2442crplU0.998
Rv0708rplP0.998
Rv3456crplQ0.998
Rv0704rplB0.998
Rv0704rplB0.998
Rv0640rplK0.997
Rv0700rpsJ0.997
Rv0640rplK0.997
Rv0706rplV0.997
Rv0720rplR0.997
Rv2441crpmA0.997
Rv0703rplW0.997
Rv0723rplO0.997
Rv1643rplT0.996
Rv1298rpmE0.996
Rv0715rplX0.996
Rv0721rpsE0.996
Rv0721rpsE0.996
Rv2889ctsf0.995
Rv0707rpsC0.995
Rv0707rpsC0.995
Rv3460crpsM0.995
Rv2889ctsf0.995
Rv2904crplS0.994
Rv0651rplJ0.994
Rv0652rplL0.993
Rv0718rpsH0.993
Rv3457crpoA0.992
Rv0705rpsS0.992
Rv3457crpoA0.992
Rv3459crpsK0.992
Rv3457crpoA0.992
Rv0683rpsG0.991
Rv0684fusA10.99
Rv0684fusA10.99
Rv3458crpsD0.99
Rv0684fusA10.99
Rv3458crpsD0.99
Rv0684fusA10.99
Rv0682rpsL0.99
Rv0684fusA10.99
Rv0056rplI0.988
Rv0056rplI0.988
Rv2882cfrr0.988
Rv0710rpsQ0.987
Rv3462cinfA0.985
Rv0732secY0.984
Rv0667rpoB0.983
Rv0667rpoB0.983
Rv0667rpoB0.983
Rv0667rpoB0.983
Rv0667rpoB0.983
Rv0667rpoB0.983
Rv1641infC0.982
Rv1641infC0.982
Rv2057crpmG10.981
Rv0722rpmD0.981
Rv3461crpmJ0.978
Rv2785crpsO0.977
Rv1015crplY0.975
Rv1015crplY0.975
Rv0634BrpmG20.975
Rv2916cffh0.972
Rv2916cffh0.972
Rv2916cffh0.972
Rv0709rpmC0.971
Rv2909crpsP0.968
Rv2412rpsT0.963
Rv0685tuf0.962
Rv0685tuf0.962
Rv0685tuf0.962
Rv2906ctrmD0.959
Rv0053rpsF0.958
Rv2056crpsN20.958
Rv2150cftsZ0.957
Rv2150cftsZ0.957
Rv2992cgltS0.952
Rv3455ctruA0.952
Rv0668rpoC0.948
Rv0668rpoC0.948
Rv0668rpoC0.948
Rv0668rpoC0.948
Rv0668rpoC0.948
Rv1017cprsA0.945
Rv1017cprsA0.945
Rv0717rpsN10.944
Rv3924crpmH0.943
Rv2534cefp0.941
Rv2534cefp0.941
Rv2534cefp0.941
Rv1630rpsA0.938
Rv2883cpyrH0.937
Rv2839cinfB0.932
Rv2839cinfB0.932
Rv1699pyrG0.932
Rv2839cinfB0.932
Rv1699pyrG0.932
Rv2839cinfB0.932
Rv0350dnaK0.931
Rv0055rpsR10.929
Rv2058crpmB20.918
Rv1023eno0.914
Rv1023eno0.914
Rv1299prfA0.909
Rv1299prfA0.909
Rv0357cpurA0.906
Rv2462ctig0.904
Rv2462ctig0.904
Rv2462ctig0.904
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.81365.409
magnesiumPubChem0.79824.305
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.707812.004
telithromycinPubChem0.707812.004
bryamycinPubChem0.7041664.89
nchembio.341-comp1PubChem0.7041664.89