Rv0651

Tuberculist information
Gene namerplJ
Protein function50S ribosomal protein L10 RplJ
Functional category(tuberculist)information pathways
Gene location(kb)748.276
Molecular mass(da)18478.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 178
	  		  	1    MARADKATAVADIAAQFKESTATLITEYRGLTVANLAELRRSLTGSATYAVAKNTLIKRA   60
			  	61   ASEAGIEGLDELFVGPTAIAFVTGEPVDAAKAIKTFAKEHKALVIKGGYMDGHPLTVAEV  120
			  	121  ERIADLESREVLLAKLAGAMKGNLAKAAGLFNAPASQLARLAAALQEKKACPGPDSAE

Known structures in the PDB
No Known structures
1 18 35 52 69 86 103 120 137 154 171 Range: 1 to 98  |  Coverage: 54% Ribosomal_L10 Range: 1 to 169  |  Coverage: 94% 1 Range: 1 to 169  |  Coverage: 94% 1
Number of amino acids : 178
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L10PF004661-98
Mtb Structural Proteome models
Model Number1
Model nameRv0651
Template1ZAV    APDBCREDO
Template coverage2_177
Template Identity(%)37.9
Model coverage(%)94.4
Normalized DOPE score0.026

Structure Models from Chopin
Model Number1
Profiled.58.62.1
Click for model details
zscore30.52
Residue begin1
Residue end169
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0651Gene nameConfidence Score
Rv0652rplL0.999
Rv0640rplK0.998
Rv0640rplK0.998
Rv0641rplA0.998
Rv0719rplF0.998
Rv0706rplV0.997
Rv0720rplR0.997
Rv0701rplC0.997
Rv0702rplD0.997
Rv0716rplE0.997
Rv0716rplE0.997
Rv0708rplP0.997
Rv0704rplB0.997
Rv0704rplB0.997
Rv0714rplN0.997
Rv0715rplX0.996
Rv0682rpsL0.996
Rv0703rplW0.996
Rv0683rpsG0.996
Rv3456crplQ0.996
Rv0723rplO0.996
Rv0718rpsH0.996
Rv0710rpsQ0.996
Rv0700rpsJ0.996
Rv0707rpsC0.995
Rv0721rpsE0.995
Rv0707rpsC0.995
Rv0721rpsE0.995
Rv3459crpsK0.995
Rv0705rpsS0.995
Rv3443crplM0.994
Rv3460crpsM0.994
Rv3458crpsD0.993
Rv3458crpsD0.993
Rv2442crplU0.993
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv3442crpsI0.988
Rv0685tuf0.988
Rv0685tuf0.988
Rv0685tuf0.988
Rv0056rplI0.987
Rv0056rplI0.987
Rv2890crpsB0.987
Rv0684fusA10.986
Rv0684fusA10.986
Rv0684fusA10.986
Rv0684fusA10.986
Rv0684fusA10.986
Rv2904crplS0.986
Rv0639nusG0.983
Rv2441crpmA0.983
Rv0639nusG0.983
Rv0634BrpmG20.981
Rv3457crpoA0.979
Rv2056crpsN20.979
Rv0709rpmC0.979
Rv3457crpoA0.979
Rv3457crpoA0.979
Rv1643rplT0.978
Rv2785crpsO0.978
Rv1630rpsA0.972
Rv0053rpsF0.971
Rv0722rpmD0.965
Rv0717rpsN10.963
Rv1015crplY0.962
Rv1015crplY0.962
Rv1298rpmE0.961
Rv0055rpsR10.96
Rv2057crpmG10.959
Rv2909crpsP0.952
Rv2889ctsf0.951
Rv2889ctsf0.951
Rv3462cinfA0.949
Rv2462ctig0.941
Rv2462ctig0.941
Rv2462ctig0.941
Rv2412rpsT0.934
Rv0732secY0.931
Rv2058crpmB20.923
Rv2839cinfB0.919
Rv2839cinfB0.919
Rv2839cinfB0.919
Rv2839cinfB0.919
Rv2906ctrmD0.917
Rv1641infC0.917
Rv1641infC0.917
Rv1017cprsA0.91
Rv1017cprsA0.91
Rv1080cgreA0.906
Rv1080cgreA0.906
Rv1308atpA0.901
Rv1308atpA0.901
Rv1308atpA0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
DrugBank IDDrug Name
DB00778DrugBankRoxithromycin
DB01190DrugBankClindamycin
DB01211DrugBankClarithromycin
DB01369DrugBankQuinupristin
DB01627DrugBankLincomycin
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
rifampicinPubChem0.709822.94