Rv1298

Tuberculist information
Gene namerpmE
Protein function50S ribosomal protein L31 RpmE
Functional category(tuberculist)information pathways
Gene location(kb)1455.16
Molecular mass(da)8753.03
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 80
	  		  	1    MKSDIHPAYEETTVVCGCGNTFQTRSTKPGGRIVVEVCSQCHPFYTGKQKILDSGGRVAR   60
			  	61   FEKRYGKRKVGADKAVSTGK

Known structures in the PDB
No Known structures
1 9 17 25 33 41 49 57 65 73 81 Range: 1 to 68  |  Coverage: 83% Ribosomal_L31 Range: 1 to 66  |  Coverage: 81% 1 Range: 1 to 52  |  Coverage: 63% 1
Number of amino acids : 80
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L31PF011971-68
Mtb Structural Proteome models
Model Number1
Model nameRv1298
Template2AW4    ZPDBCREDO
Template coverage1_65
Template Identity(%)56.9
Model coverage(%)81.2
Normalized DOPE score1.273

Structure Models from Chopin
Model Number1
Profiled.325.1.2
Click for model details
zscore15.59
Residue begin1
Residue end52
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1298Gene nameConfidence Score
Rv3443crplM0.996
Rv2441crpmA0.995
Rv2904crplS0.995
Rv2442crplU0.994
Rv2057crpmG10.99
Rv3456crplQ0.985
Rv1643rplT0.981
Rv0708rplP0.98
Rv0056rplI0.979
Rv3442crpsI0.979
Rv0056rplI0.979
Rv2882cfrr0.978
Rv0723rplO0.977
Rv1297rho0.976
Rv1297rho0.976
Rv1297rho0.976
Rv0720rplR0.974
Rv0702rplD0.974
Rv0703rplW0.974
Rv0719rplF0.972
Rv0706rplV0.972
Rv0640rplK0.972
Rv0715rplX0.972
Rv0640rplK0.972
Rv0714rplN0.971
Rv1299prfA0.971
Rv1299prfA0.971
Rv0716rplE0.969
Rv0701rplC0.969
Rv0716rplE0.969
Rv3460crpsM0.968
Rv0704rplB0.965
Rv0641rplA0.965
Rv0704rplB0.965
Rv0634BrpmG20.964
Rv1015crplY0.964
Rv1015crplY0.964
Rv2909crpsP0.962
Rv0651rplJ0.961
Rv2916cffh0.955
Rv2916cffh0.955
Rv2916cffh0.955
Rv2412rpsT0.951
Rv3458crpsD0.95
Rv3458crpsD0.95
Rv0652rplL0.948
Rv3924crpmH0.948
Rv0055rpsR10.942
Rv0722rpmD0.938
Rv1300hemK0.937
Rv2058crpmB20.936
Rv2906ctrmD0.936
Rv2785crpsO0.936
Rv2890crpsB0.925
Rv0684fusA10.922
Rv0684fusA10.922
Rv0684fusA10.922
Rv0684fusA10.922
Rv0684fusA10.922
Rv0700rpsJ0.92
Rv2907crimM0.911
Rv2907crimM0.911
Rv2889ctsf0.909
Rv0682rpsL0.909
Rv2889ctsf0.909
Rv3459crpsK0.906
Rv3309cupp0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.85965.409
magnesiumPubChem0.78824.305
telithromycinPubChem0.707812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.707812.004