Rv0634B

Tuberculist information
Gene namerpmG2
Protein function50S ribosomal protein L33 RpmG2
Functional category(tuberculist)information pathways
Gene location(kb)731.712
Molecular mass(da)6495.51
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 55
	  		  	1    MASSTDVRPKITLACEVCKHRNYITKKNRRNDPDRLELKKFCPNCGKHQAHRETR

Known structures in the PDB
No Known structures
1 6 11 16 21 26 31 36 41 46 51 Range: 8 to 55  |  Coverage: 85% Ribosomal_L33 Range: 4 to 55  |  Coverage: 92% 1 Range: 6 to 55  |  Coverage: 89% 1
Number of amino acids : 55
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L33PF004718-55
Mtb Structural Proteome models
Model Number1
Model nameRv0634B
Template2AW4    1PDBCREDO
Template coverage1_52
Template Identity(%)36.5
Model coverage(%)92.7
Normalized DOPE score0.501

Structure Models from Chopin
Model Number1
Profileg.41.8.6
Click for model details
zscore13.87
Residue begin6
Residue end55
Binding pockets
STRING
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Protein interacting with Rv0634BGene nameConfidence Score
Rv0641rplA0.99
Rv0640rplK0.989
Rv0640rplK0.989
Rv0708rplP0.988
Rv0652rplL0.988
Rv0714rplN0.985
Rv0703rplW0.983
Rv0055rpsR10.982
Rv0651rplJ0.981
Rv0704rplB0.976
Rv0704rplB0.976
Rv3443crplM0.975
Rv0639nusG0.974
Rv0639nusG0.974
Rv2055crpsR20.973
Rv0706rplV0.97
Rv0701rplC0.969
Rv3456crplQ0.965
Rv0723rplO0.965
Rv1298rpmE0.964
Rv0717rpsN10.961
Rv0719rplF0.959
Rv0702rplD0.959
Rv0683rpsG0.957
Rv0056rplI0.955
Rv2904crplS0.955
Rv0056rplI0.955
Rv0716rplE0.954
Rv0716rplE0.954
Rv0700rpsJ0.947
Rv0682rpsL0.947
Rv2441crpmA0.939
Rv2442crplU0.939
Rv1643rplT0.939
Rv0720rplR0.932
Rv3442crpsI0.93
Rv0715rplX0.925
Rv0053rpsF0.921
Rv0667rpoB0.92
Rv0667rpoB0.92
Rv0667rpoB0.92
Rv0667rpoB0.92
Rv0667rpoB0.92
Rv0667rpoB0.92
Rv1015crplY0.914
Rv1015crplY0.914
Rv0668rpoC0.91
Rv0668rpoC0.91
Rv0668rpoC0.91
Rv0668rpoC0.91
Rv0668rpoC0.91
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.82965.409
telithromycinPubChem0.708812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.708812.004
magnesiumPubChem0.70824.305