Rv2442c

Tuberculist information
Gene namerplU
Protein function50S ribosomal protein L21 RplU
Functional category(tuberculist)information pathways
Gene location(kb)2740.05
Molecular mass(da)11151.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 104
	  		  	1    MMATYAIVKTGGKQYKVAVGDVVKVEKLESEQGEKVSLPVALVVDGATVTTDAKALAKVA   60
			  	61   VTGEVLGHTKGPKIRIHKFKNKTGYHKRQGHRQQLTVLKVTGIA

Known structures in the PDB
No Known structures
1 11 21 31 41 51 61 71 81 91 101 Range: 3 to 97  |  Coverage: 90% Ribosomal_L21p Range: 4 to 103  |  Coverage: 95% 1 Range: 4 to 104  |  Coverage: 96% 1
Number of amino acids : 104
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L21pPF008293-97
Mtb Structural Proteome models
Model Number1
Model nameRv2442c
Template1NKW    PPDBCREDO
Template coverage1_98
Template Identity(%)46.9
Model coverage(%)95.2
Normalized DOPE score1.605

Structure Models from Chopin
Model Number1
Profileb.155.1.1
Click for model details
zscore25.9
Residue begin4
Residue end104
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2442cGene nameConfidence Score
Rv2916cffh0.999
Rv2441crpmA0.999
Rv2916cffh0.999
Rv2916cffh0.999
Rv3443crplM0.998
Rv0719rplF0.996
Rv0723rplO0.995
Rv0706rplV0.994
Rv1298rpmE0.994
Rv2904crplS0.994
Rv0720rplR0.994
Rv0702rplD0.993
Rv0651rplJ0.993
Rv0714rplN0.993
Rv0716rplE0.992
Rv0716rplE0.992
Rv0641rplA0.992
Rv0640rplK0.991
Rv0701rplC0.991
Rv0640rplK0.991
Rv0708rplP0.991
Rv0704rplB0.99
Rv0056rplI0.99
Rv0704rplB0.99
Rv0056rplI0.99
Rv3456crplQ0.99
Rv0715rplX0.99
Rv0703rplW0.989
Rv0652rplL0.988
Rv2057crpmG10.988
Rv2909crpsP0.987
Rv0721rpsE0.984
Rv0721rpsE0.984
Rv3442crpsI0.984
Rv1643rplT0.984
Rv1015crplY0.984
Rv1015crplY0.984
Rv2440cobg0.983
Rv2440cobg0.983
Rv0718rpsH0.983
Rv2440cobg0.983
Rv2439cproB0.978
Rv2439cproB0.978
Rv2412rpsT0.973
Rv2785crpsO0.973
Rv0700rpsJ0.972
Rv2890crpsB0.966
Rv0722rpmD0.963
Rv0684fusA10.961
Rv0684fusA10.961
Rv0684fusA10.961
Rv3460crpsM0.961
Rv0684fusA10.961
Rv0684fusA10.961
Rv2906ctrmD0.959
Rv3458crpsD0.958
Rv3458crpsD0.958
Rv0707rpsC0.957
Rv0053rpsF0.957
Rv0707rpsC0.957
Rv0682rpsL0.956
Rv0683rpsG0.956
Rv3459crpsK0.953
Rv0055rpsR10.951
Rv1641infC0.949
Rv1641infC0.949
Rv2889ctsf0.949
Rv0705rpsS0.949
Rv2889ctsf0.949
Rv2058crpmB20.947
Rv0634BrpmG20.939
Rv2427cproA0.938
Rv3924crpmH0.935
Rv2882cfrr0.932
Rv2055crpsR20.926
Rv0710rpsQ0.923
Rv0732secY0.922
Rv3436cglmS0.916
Rv3436cglmS0.916
Rv0717rpsN10.913
Rv3628ppa0.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.79724.305
zincPubChem0.79765.409
telithromycinPubChem0.702812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.702812.004