Rv0683

Tuberculist information
Gene namerpsG
Protein function30S ribosomal protein S7 RpsG
Functional category(tuberculist)information pathways
Gene location(kb)781.934
Molecular mass(da)17600.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 156
	  		  	1    MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLKGKKSLAERIVYGALEQARDKTGTDPVI   60
			  	61   TLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWLVGYSRQRREKTMIERL  120
			  	121  ANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW

Known structures in the PDB
No Known structures
1 16 31 46 61 76 91 106 121 136 151 Range: 1 to 149  |  Coverage: 94% Ribosomal_S7 Range: 10 to 148  |  Coverage: 88% 1 Range: 1 to 154  |  Coverage: 98% 1
Number of amino acids : 156
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_S7PF001771-149
Mtb Structural Proteome models
Model Number1
Model nameRv0683
Template1HUS    APDBCREDO
Template coverage9_147
Template Identity(%)63.3
Model coverage(%)88.5
Normalized DOPE score-1.628

Structure Models from Chopin
Model Number1
Profilea.75.1.1 - 1.10.455.10
Click for model details
zscore30.65
Residue begin1
Residue end154
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0683Gene nameConfidence Score
Rv0682rpsL0.999
Rv3458crpsD0.999
Rv0685tuf0.999
Rv3458crpsD0.999
Rv0685tuf0.999
Rv0707rpsC0.999
Rv0707rpsC0.999
Rv0685tuf0.999
Rv0684fusA10.998
Rv0718rpsH0.998
Rv0684fusA10.998
Rv0705rpsS0.998
Rv0700rpsJ0.998
Rv0684fusA10.998
Rv3460crpsM0.998
Rv0684fusA10.998
Rv0721rpsE0.998
Rv0684fusA10.998
Rv0721rpsE0.998
Rv2890crpsB0.997
Rv0652rplL0.997
Rv0710rpsQ0.997
Rv3459crpsK0.997
Rv0716rplE0.997
Rv0716rplE0.997
Rv3442crpsI0.997
Rv0667rpoB0.996
Rv0717rpsN10.996
Rv0667rpoB0.996
Rv0667rpoB0.996
Rv0667rpoB0.996
Rv3457crpoA0.996
Rv0667rpoB0.996
Rv3457crpoA0.996
Rv0667rpoB0.996
Rv3457crpoA0.996
Rv0651rplJ0.996
Rv0704rplB0.995
Rv0704rplB0.995
Rv0641rplA0.995
Rv0701rplC0.994
Rv3456crplQ0.993
Rv0706rplV0.993
Rv0702rplD0.993
Rv2056crpsN20.993
Rv0719rplF0.992
Rv0640rplK0.992
Rv0640rplK0.992
Rv2785crpsO0.991
Rv3443crplM0.991
Rv0714rplN0.991
Rv0723rplO0.99
Rv0720rplR0.99
Rv0715rplX0.99
Rv0053rpsF0.99
Rv0703rplW0.99
Rv0708rplP0.99
Rv0639nusG0.988
Rv0668rpoC0.988
Rv0639nusG0.988
Rv0668rpoC0.988
Rv0668rpoC0.988
Rv0668rpoC0.988
Rv0668rpoC0.988
Rv0732secY0.985
Rv0055rpsR10.985
Rv2909crpsP0.984
Rv1641infC0.984
Rv1641infC0.984
Rv2412rpsT0.982
Rv0120cfusA20.98
Rv0120cfusA20.98
Rv0120cfusA20.98
Rv0120cfusA20.98
Rv0120cfusA20.98
Rv0722rpmD0.978
Rv3462cinfA0.977
Rv2889ctsf0.971
Rv2889ctsf0.971
Rv1630rpsA0.97
Rv2882cfrr0.968
Rv0709rpmC0.967
Rv2441crpmA0.967
Rv0056rplI0.965
Rv0056rplI0.965
Rv0634BrpmG20.957
Rv2442crplU0.956
Rv2534cefp0.951
Rv2534cefp0.951
Rv2534cefp0.951
Rv3100csmpB0.949
Rv0733adk0.947
Rv2462ctig0.942
Rv2462ctig0.942
Rv2462ctig0.942
Rv1080cgreA0.941
Rv1080cgreA0.941
Rv2906ctrmD0.94
Rv2841cnusA0.939
Rv2841cnusA0.939
Rv2904crplS0.937
Rv1643rplT0.935
Rv2992cgltS0.929
Rv1292argS0.922
Rv1292argS0.922
Rv1292argS0.922
Rv2614cthrS0.917
Rv2614cthrS0.917
Rv2614cthrS0.917
Rv1112Rv11120.916
Rv1112Rv11120.916
Rv1015crplY0.912
Rv1015crplY0.912
Rv1023eno0.91
Rv1023eno0.91
Rv2057crpmG10.908
Rv1299prfA0.907
Rv1299prfA0.907
Rv1699pyrG0.905
Rv1699pyrG0.905
Rv1649pheS0.903
Rv3455ctruA0.903
Rv1649pheS0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
DrugBank IDDrug Name
DB00759DrugBankTetracycline
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
kirromycinPubChem0.884796.943
streptomycinPubChem0.826581.574
spectinomycinPubChem0.794332.35
guanosine diphosphatePubChem0.788443.201
magnesiumPubChem0.78824.305
guanylatePubChem0.711363.221
2-mercaptoethanolPubChem0.7178.1334
kasugamycinPubChem0.707379.363
2,3-diaminopropionic acidPubChem0.707104.108
CSIPubChem0.707172.185
phenylalaninalPubChem0.707149.19
MYC-8003PubChem0.707796.943
7mgPubChem0.707379.263
UD29PubChem0.707340.247
[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl phosphatePubChem0.707338.208
2'-O-methylguanosine 5'-monophosphatePubChem0.707377.247
potassiumPubChem0.70739.0983
L-2,3-diaminopropionic acidPubChem0.707104.108
3'-phosphoadenosine 5'-phosphatePubChem0.707427.201
[5-(2-dimethylamino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic AcidPubChem0.707391.274
poly(2'-O-methylcytidylic acid)PubChem0.707337.223
pseudouridylic acidPubChem0.707324.181
L-beta-lysinePubChem0.707146.188
zincPubChem0.70765.409
poly CPubChem0.707323.197
DB08185PubChem0.707463.446
3'-amino-3'-deoxy AMPPubChem0.707346.236
CHEBI:603702PubChem0.707558.623
poly(2'-O-methyladenylic acid)PubChem0.707361.248
beta-lysinePubChem0.707146.188
methyl 4-[3-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-PubChem0.707588.462
fusidic acidPubChem0.707516.709
[(2R,3S,4R,5R)-5-[2-(dimethylamino)-6-oxo-3H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen PubChem0.707391.274
ara-TMPPubChem0.707338.208
potassium hydridePubChem0.70740.1062
guanylyl-(alpha,beta)-methylene-diphosphonatePubChem0.707521.208
C07026PubChem0.707346.236
[3,4-dihydroxy-5-(2-methylamino-6-oxo-3H-purin-9-yl)oxolan-2-yl]methoxyphosphonic AcidPubChem0.707377.247
5-methylcytidylic acidPubChem0.707337.223
adenosine 3',5'-diphosphatePubChem0.707427.201
pactamycinPubChem0.707558.623
adenosine monophosphatePubChem0.707347.221
[3,4-dihydroxy-5-(6-imino-1-methyl-purin-9-yl)oxolan-2-yl]methoxyphosphonic AcidPubChem0.707361.248
C04639PubChem0.707326.197
polyuridylic acidPubChem0.707324.181
pseudouridine 5'-phosphatePubChem0.707324.181