Rv3100c

Tuberculist information
Gene namesmpB
Protein functionProbable SSRA-binding protein SmpB
Functional category(tuberculist)virulence,detoxification and adaptaion
Gene location(kb)3469.3
Molecular mass(da)18197.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 160
	  		  	1    VSKSSRGGRQIVASNRKARHNYSIIEVFEAGVALQGTEVKSLREGQASLADSFATIDDGE   60
			  	61   VWLRNAHIPEYRHGSWTNHEPRRNRKLLLHRRQIDTLVGKIREGNFALVPLSLYFAEGKV  120
			  	121  KVELALARGKQARDKRQDMARRDAQREVLRELGRRAKGMT

Known structures in the PDB
No Known structures
1 17 33 49 65 81 97 113 129 145 161 Range: 10 to 77  |  Coverage: 41% SmpB Range: 12 to 132  |  Coverage: 75% 1 Range: 6 to 132  |  Coverage: 78% 1
Number of amino acids : 160
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
SmpBPF0166810-77
Mtb Structural Proteome models
Model Number1
Model nameRv3100c
Template1P6V    APDBCREDO
Template coverage9_130
Template Identity(%)51.3
Model coverage(%)74.5
Normalized DOPE score-0.759

Structure Models from Chopin
Model Number1
Profileb.111.1.1 - 2.40.280.10
Click for model details
zscore33.21
Residue begin6
Residue end132
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3100cGene nameConfidence Score
Rv0707rpsC0.984
Rv0707rpsC0.984
Rv3459crpsK0.981
Rv3458crpsD0.98
Rv3458crpsD0.98
Rv3460crpsM0.979
Rv0700rpsJ0.963
Rv0721rpsE0.962
Rv0721rpsE0.962
Rv0705rpsS0.96
Rv2841cnusA0.959
Rv2841cnusA0.959
Rv2904crplS0.954
Rv3442crpsI0.953
Rv2440cobg0.949
Rv2440cobg0.949
Rv2440cobg0.949
Rv0683rpsG0.949
Rv2890crpsB0.943
Rv0006gyrA0.939
Rv0682rpsL0.939
Rv0006gyrA0.939
Rv3457crpoA0.938
Rv3457crpoA0.938
Rv3457crpoA0.938
Rv3834cserS0.936
Rv1699pyrG0.936
Rv1699pyrG0.936
Rv3834cserS0.936
Rv1650pheT0.926
Rv1650pheT0.926
Rv1650pheT0.926
Rv1650pheT0.926
Rv2364cera0.925
Rv2364cera0.925
Rv1014cpth0.921
Rv0053rpsF0.912
Rv2555calaS0.908
Rv2555calaS0.908
Rv2555calaS0.908
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
potassiumPubChem0.70439.0983
potassium hydridePubChem0.70440.1062