Rv0707

Tuberculist information
Gene namerpsC
Protein function30S ribosomal protein S3 RpsC
Functional category(tuberculist)information pathways
Gene location(kb)804.282
Molecular mass(da)29987.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 274
	  		  	1    VGQKINPHGFRLGITTDWKSRWYADKQYAEYVKEDVAIRRLLSSGLERAGIADVEIERTR   60
			  	61   DRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTGKQVQLNILEVKNPESQAQLVAQGVA  120
			  	121  EQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRA  180
			  	181  DIDYGLYEAKTTFGRIGVKVWIYKGDIVGGKRELAAAAPAGADRPRRERPSGTRPRRSGA  240
			  	241  SGTTATGTDAGRAAGGEEAAPDAAAPVEAQSTES

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 37 to 110  |  Coverage: 26% KH_2 Range: 118 to 202  |  Coverage: 30% Ribosomal_S3_C Range: 2 to 207  |  Coverage: 74% 1 Range: 106 to 207  |  Coverage: 36% 1 Range: 17 to 128  |  Coverage: 40% 2
Number of amino acids : 274
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
KH_2PF0765037-110
Ribosomal_S3_CPF00189118-202
Mtb Structural Proteome models
Model Number1
Model nameRv0707
Template1FJG    CPDBCREDO
Template coverage2_207
Template Identity(%)54.9
Model coverage(%)74.8
Normalized DOPE score-0.576

Structure Models from Chopin
Model Number1
Profiled.53.1.1
Click for model details
zscore28.02
Residue begin106
Residue end207
Model Number2
Profile3.30.300.20
Click for model details
zscore12.02
Residue begin17
Residue end128
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0707Gene nameConfidence Score
Rv3458crpsD0.999
Rv0704rplB0.999
Rv3458crpsD0.999
Rv0705rpsS0.999
Rv0721rpsE0.999
Rv3459crpsK0.999
Rv0706rplV0.999
Rv0721rpsE0.999
Rv3460crpsM0.999
Rv0701rplC0.999
Rv0708rplP0.999
Rv0702rplD0.999
Rv0703rplW0.999
Rv0710rpsQ0.999
Rv3442crpsI0.999
Rv0683rpsG0.999
Rv0704rplB0.999
Rv0714rplN0.998
Rv0640rplK0.998
Rv0700rpsJ0.998
Rv0640rplK0.998
Rv0709rpmC0.998
Rv0682rpsL0.998
Rv0718rpsH0.998
Rv0716rplE0.997
Rv0716rplE0.997
Rv3457crpoA0.997
Rv0717rpsN10.997
Rv3457crpoA0.997
Rv3457crpoA0.997
Rv0652rplL0.997
Rv0668rpoC0.996
Rv0668rpoC0.996
Rv0668rpoC0.996
Rv0668rpoC0.996
Rv0668rpoC0.996
Rv0719rplF0.995
Rv0685tuf0.995
Rv0667rpoB0.995
Rv3443crplM0.995
Rv0685tuf0.995
Rv0667rpoB0.995
Rv0667rpoB0.995
Rv0667rpoB0.995
Rv0641rplA0.995
Rv2056crpsN20.995
Rv0667rpoB0.995
Rv0651rplJ0.995
Rv0667rpoB0.995
Rv0685tuf0.995
Rv0684fusA10.993
Rv0684fusA10.993
Rv3456crplQ0.993
Rv0684fusA10.993
Rv0684fusA10.993
Rv0684fusA10.993
Rv0715rplX0.992
Rv0720rplR0.991
Rv0723rplO0.991
Rv0732secY0.991
Rv2890crpsB0.99
Rv2785crpsO0.99
Rv0053rpsF0.987
Rv0722rpmD0.985
Rv3100csmpB0.984
Rv1641infC0.984
Rv1641infC0.984
Rv2882cfrr0.982
Rv2889ctsf0.982
Rv2889ctsf0.982
Rv2904crplS0.979
Rv0639nusG0.978
Rv3462cinfA0.978
Rv0639nusG0.978
Rv2441crpmA0.975
Rv1643rplT0.974
Rv0734mapA0.972
Rv2909crpsP0.972
Rv2412rpsT0.965
Rv2861cmapB0.96
Rv2442crplU0.957
Rv2462ctig0.955
Rv2462ctig0.955
Rv2462ctig0.955
Rv0056rplI0.952
Rv0056rplI0.952
Rv0733adk0.951
Rv2841cnusA0.949
Rv2841cnusA0.949
Rv1630rpsA0.948
Rv2906ctrmD0.946
Rv2839cinfB0.941
Rv2839cinfB0.941
Rv2839cinfB0.941
Rv2839cinfB0.941
Rv0055rpsR10.94
Rv2534cefp0.939
Rv2534cefp0.939
Rv2534cefp0.939
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv0120cfusA20.932
Rv0120cfusA20.932
Rv0120cfusA20.932
Rv0120cfusA20.932
Rv0120cfusA20.932
Rv1023eno0.92
Rv1023eno0.92
Rv2364cera0.915
Rv2057crpmG10.915
Rv2364cera0.915
Rv1297rho0.912
Rv1297rho0.912
Rv1297rho0.912
Rv3455ctruA0.908
Rv1649pheS0.908
Rv1649pheS0.908
Rv1308atpA0.907
Rv1308atpA0.907
Rv1308atpA0.907
Rv0001dnaA0.906
Rv0001dnaA0.906
Rv3461crpmJ0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
DrugBank IDDrug Name
DB00759DrugBankTetracycline
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
spectinomycinPubChem0.788332.35
guanosine diphosphatePubChem0.788443.201
magnesiumPubChem0.78824.305
streptomycinPubChem0.734581.574
kasugamycinPubChem0.703379.363
2,3-diaminopropionic acidPubChem0.703104.108
CSIPubChem0.703172.185
phenylalaninalPubChem0.703149.19
MYC-8003PubChem0.703796.943
7mgPubChem0.703379.263
UD29PubChem0.703340.247
kirromycinPubChem0.703796.943
[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl phosphatePubChem0.703338.208
2'-O-methylguanosine 5'-monophosphatePubChem0.703377.247
potassiumPubChem0.70339.0983
L-2,3-diaminopropionic acidPubChem0.703104.108
3'-phosphoadenosine 5'-phosphatePubChem0.703427.201
[5-(2-dimethylamino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic AcidPubChem0.703391.274
poly(2'-O-methylcytidylic acid)PubChem0.703337.223
pseudouridylic acidPubChem0.703324.181
L-beta-lysinePubChem0.703146.188
zincPubChem0.70365.409
poly CPubChem0.703323.197
DB08185PubChem0.703463.446
3'-amino-3'-deoxy AMPPubChem0.703346.236
2-mercaptoethanolPubChem0.70378.1334
CHEBI:603702PubChem0.703558.623
poly(2'-O-methyladenylic acid)PubChem0.703361.248
beta-lysinePubChem0.703146.188
methyl 4-[3-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-PubChem0.703588.462
fusidic acidPubChem0.703516.709
[(2R,3S,4R,5R)-5-[2-(dimethylamino)-6-oxo-3H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen PubChem0.703391.274
ara-TMPPubChem0.703338.208
guanylatePubChem0.703363.221
potassium hydridePubChem0.70340.1062
guanylyl-(alpha,beta)-methylene-diphosphonatePubChem0.703521.208
C07026PubChem0.703346.236
[3,4-dihydroxy-5-(2-methylamino-6-oxo-3H-purin-9-yl)oxolan-2-yl]methoxyphosphonic AcidPubChem0.703377.247
5-methylcytidylic acidPubChem0.703337.223
adenosine 3',5'-diphosphatePubChem0.703427.201
pactamycinPubChem0.703558.623
adenosine monophosphatePubChem0.703347.221
[3,4-dihydroxy-5-(6-imino-1-methyl-purin-9-yl)oxolan-2-yl]methoxyphosphonic AcidPubChem0.703361.248
C04639PubChem0.703326.197
polyuridylic acidPubChem0.703324.181
pseudouridine 5'-phosphatePubChem0.703324.181