Rv2534c

Tuberculist information
Gene nameefp
Protein functionProbable elongation factor P Efp
Functional category(tuberculist)information pathways
Gene location(kb)2858.73
Molecular mass(da)20375.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 187
	  		  	1    VATTADFKNGLVLVIDGQLWTITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKV   60
			  	61   DTATVDRRDTTYLYRDGSDFVFMDSQDYEQHPLPEALVGDAARFLLEGMPVQVAFHNGVP  120
			  	121  LYIELPVTVELEVTHTEPGLQGDRSSAGTKPATLQTGAQINVPLFINTGDKLKVDSRDGS  180
			  	181  YLGRVNA

Known structures in the PDB
No Known structures
1 19 37 55 73 91 109 127 145 163 181 Range: 3 to 60  |  Coverage: 30% EFP_N Range: 67 to 121  |  Coverage: 28% EFP Range: 129 to 184  |  Coverage: 29% Elong-fact-P_C Range: 1 to 185  |  Coverage: 98% 1 Range: 1 to 72  |  Coverage: 37% 1
Number of amino acids : 187
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
EFP_NPF082073-60
EFPPF0113267-121
Elong-fact-P_CPF09285129-184
Mtb Structural Proteome models
Model Number1
Model nameRv2534c
Template1UEB    APDBCREDO
Template coverage1_184
Template Identity(%)43.5
Model coverage(%)98.4
Normalized DOPE score-0.657

Structure Models from Chopin
Model Number1
Profileb.34.5.2
Click for model details
zscore8.13
Residue begin1
Residue end72
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2534cGene nameConfidence Score
Rv2533cnusB0.984
Rv2535cpepQ0.984
Rv2535cpepQ0.984
Rv3442crpsI0.976
Rv0700rpsJ0.971
Rv1630rpsA0.957
Rv2890crpsB0.956
Rv0683rpsG0.951
Rv0056rplI0.95
Rv0056rplI0.95
Rv0053rpsF0.949
Rv2537caroD0.948
Rv0716rplE0.945
Rv3458crpsD0.945
Rv0716rplE0.945
Rv3458crpsD0.945
Rv3460crpsM0.944
Rv3443crplM0.941
Rv2404clepA0.94
Rv2404clepA0.94
Rv2404clepA0.94
Rv2404clepA0.94
Rv2909crpsP0.939
Rv0707rpsC0.939
Rv0707rpsC0.939
Rv2785crpsO0.939
Rv1699pyrG0.937
Rv1699pyrG0.937
Rv0721rpsE0.936
Rv0721rpsE0.936
Rv2889ctsf0.935
Rv2889ctsf0.935
Rv3459crpsK0.934
Rv0682rpsL0.934
Rv0718rpsH0.93
Rv3336ctrpS0.93
Rv0710rpsQ0.929
Rv2462ctig0.924
Rv2462ctig0.924
Rv2462ctig0.924
Rv2584capt0.923
Rv1007cmetS0.922
Rv1437pgk0.922
Rv3462cinfA0.918
Rv0685tuf0.916
Rv0685tuf0.916
Rv0685tuf0.916
Rv2727cmiaA0.915
Rv1649pheS0.911
Rv1649pheS0.911
Rv2904crplS0.908
Rv0705rpsS0.907
Rv1449ctkt0.903
Rv1449ctkt0.903
Rv1449ctkt0.903
Rv1015crplY0.901
Rv1015crplY0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.77724.305
fMetPubChem0.751177.221
selenomethioninePubChem0.708196.106
SeMetPubChem0.708196.106
zincPubChem0.70265.409