Rv2785c

Tuberculist information
Gene namerpsO
Protein function30S ribosomal protein S15 RpsO
Functional category(tuberculist)information pathways
Gene location(kb)3093.48
Molecular mass(da)10443.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 89
	  		  	1    VALTAEQKKEILRSYGLHETDTGSPEAQIALLTKRIADLTEHLKVHKHDHHSRRGLLLLV   60
			  	61   GRRRRLIKYISQIDVERYRSLIERLGLRR

Known structures in the PDB
No Known structures
1 9 17 25 33 41 49 57 65 73 81 Range: 6 to 88  |  Coverage: 92% Ribosomal_S15 Range: 3 to 87  |  Coverage: 94% 1 Range: 2 to 89  |  Coverage: 97% 1
Number of amino acids : 89
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_S15PF003126-88
Mtb Structural Proteome models
Model Number1
Model nameRv2785c
Template1A32    APDBCREDO
Template coverage2_86
Template Identity(%)61.2
Model coverage(%)93.3
Normalized DOPE score-0.649

Structure Models from Chopin
Model Number1
Profilea.16.1.2 - 1.10.287.10
Click for model details
zscore23.14
Residue begin2
Residue end89
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2785cGene nameConfidence Score
Rv2793ctruB0.997
Rv2793ctruB0.997
Rv2783cgpsI0.995
Rv2783cgpsI0.995
Rv2783cgpsI0.995
Rv2412rpsT0.995
Rv2783cgpsI0.995
Rv2783cgpsI0.995
Rv2786cribF0.994
Rv2786cribF0.994
Rv0700rpsJ0.993
Rv3442crpsI0.992
Rv0053rpsF0.991
Rv2890crpsB0.991
Rv0682rpsL0.991
Rv0683rpsG0.991
Rv0707rpsC0.99
Rv0707rpsC0.99
Rv0718rpsH0.989
Rv3458crpsD0.988
Rv0721rpsE0.988
Rv3459crpsK0.988
Rv0710rpsQ0.988
Rv3458crpsD0.988
Rv0721rpsE0.988
Rv3460crpsM0.987
Rv2839cinfB0.986
Rv2839cinfB0.986
Rv2882cfrr0.986
Rv2839cinfB0.986
Rv2839cinfB0.986
Rv0705rpsS0.985
Rv2909crpsP0.984
Rv0651rplJ0.978
Rv0702rplD0.978
Rv3443crplM0.977
Rv1641infC0.976
Rv1641infC0.976
Rv0685tuf0.976
Rv0685tuf0.976
Rv0685tuf0.976
Rv2904crplS0.975
Rv2889ctsf0.974
Rv2889ctsf0.974
Rv2442crplU0.973
Rv0056rplI0.97
Rv0056rplI0.97
Rv2441crpmA0.963
Rv0701rplC0.961
Rv3456crplQ0.957
Rv0720rplR0.957
Rv1643rplT0.955
Rv0708rplP0.949
Rv0704rplB0.949
Rv0704rplB0.949
Rv0684fusA10.948
Rv0684fusA10.948
Rv0723rplO0.948
Rv0684fusA10.948
Rv2838crbfA0.948
Rv0684fusA10.948
Rv0684fusA10.948
Rv0717rpsN10.947
Rv2056crpsN20.947
Rv3457crpoA0.944
Rv3457crpoA0.944
Rv0640rplK0.944
Rv3457crpoA0.944
Rv0640rplK0.944
Rv2906ctrmD0.943
Rv0714rplN0.942
Rv0706rplV0.941
Rv0719rplF0.941
Rv2534cefp0.939
Rv2534cefp0.939
Rv2534cefp0.939
Rv0703rplW0.937
Rv1298rpmE0.936
Rv2753cdapA0.934
Rv0055rpsR10.928
Rv0641rplA0.928
Rv0716rplE0.921
Rv0716rplE0.921
Rv0667rpoB0.917
Rv0667rpoB0.917
Rv2841cnusA0.917
Rv0667rpoB0.917
Rv2841cnusA0.917
Rv0667rpoB0.917
Rv0667rpoB0.917
Rv0667rpoB0.917
Rv2462ctig0.915
Rv2462ctig0.915
Rv2462ctig0.915
Rv0041leuS0.912
Rv0041leuS0.912
Rv0041leuS0.912
Rv0652rplL0.908
Rv2883cpyrH0.907
Rv1292argS0.903
Rv1292argS0.903
Rv1292argS0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.81324.305
guanosine diphosphatePubChem0.788443.201
spectinomycinPubChem0.788332.35
zincPubChem0.71865.409
kasugamycinPubChem0.708379.363
L-2,3-diaminopropionic acidPubChem0.708104.108
CSIPubChem0.708172.185
phenylalaninalPubChem0.708149.19
fusidic acidPubChem0.708516.709
hydron sulfatePubChem0.708196.157
7mgPubChem0.708379.263
potassiumPubChem0.70839.0983
adenosine 3',5'-diphosphatePubChem0.708427.201
UD29PubChem0.708340.247
guanylyl-(alpha,beta)-methylene-diphosphonatePubChem0.708521.208
3'-phosphoadenosine 5'-phosphatePubChem0.708427.201
2'-O-methylguanosine 5'-monophosphatePubChem0.708377.247
pseudouridylic acidPubChem0.708324.181
pseudouridine 5'-phosphatePubChem0.708324.181
pactamycinPubChem0.708558.623
poly CPubChem0.708323.197
[5-(2-dimethylamino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic AcidPubChem0.708391.274
poly(2'-O-methylcytidylic acid)PubChem0.708337.223
polyuridylic acidPubChem0.708324.181
MYC-8003PubChem0.708796.943
beta-lysinePubChem0.708146.188
potassium hydridePubChem0.70840.1062
DB08185PubChem0.708463.446
3'-amino-3'-deoxy AMPPubChem0.708346.236
[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl phosphatePubChem0.708338.208
poly(2'-O-methyladenylic acid)PubChem0.708361.248
guanylatePubChem0.708363.221
SeMetPubChem0.708196.106
methyl 4-[3-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-PubChem0.708588.462
kirromycinPubChem0.708796.943
C07026PubChem0.708346.236
ara-TMPPubChem0.708338.208
L-beta-lysinePubChem0.708146.188
streptomycinPubChem0.708581.574
adenosine monophosphatePubChem0.708347.221
[3,4-dihydroxy-5-(2-methylamino-6-oxo-3H-purin-9-yl)oxolan-2-yl]methoxyphosphonic AcidPubChem0.708377.247
5-methylcytidylic acidPubChem0.708337.223
sulfatePubChem0.70896.0626
CHEBI:603702PubChem0.708558.623
selenomethioninePubChem0.708196.106
2,3-diaminopropionic acidPubChem0.708104.108
[3,4-dihydroxy-5-(6-imino-1-methyl-purin-9-yl)oxolan-2-yl]methoxyphosphonic AcidPubChem0.708361.248
C04639PubChem0.708326.197
2-mercaptoethanolPubChem0.70878.1334
[(2R,3S,4R,5R)-5-[2-(dimethylamino)-6-oxo-3H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen PubChem0.708391.274