Rv2441c

Tuberculist information
Gene namerpmA
Protein function50S ribosomal protein L27 RpmA
Functional category(tuberculist)information pathways
Gene location(kb)2739.77
Molecular mass(da)8968.23
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 86
	  		  	1    MAHKKGASSSRNGRDSAAQRLGVKRYGGQVVKAGEILVRQRGTKFHPGVNVGRGGDDTLF   60
			  	61   AKTAGAVEFGIKRGRKTVSIVGSTTA

Known structures in the PDB
No Known structures
1 9 17 25 33 41 49 57 65 73 81 Range: 2 to 81  |  Coverage: 91% Ribosomal_L27 Range: 2 to 80  |  Coverage: 90% 1
Number of amino acids : 86
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L27PF010162-81
Mtb Structural Proteome models
Model Number1
Model nameRv2441c
Template2AW4    WPDBCREDO
Template coverage1_81
Template Identity(%)65.8
Model coverage(%)90.7
Normalized DOPE score1.549

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2441cGene nameConfidence Score
Rv2916cffh0.999
Rv2916cffh0.999
Rv2442crplU0.999
Rv2916cffh0.999
Rv3443crplM0.997
Rv0641rplA0.996
Rv2904crplS0.996
Rv0640rplK0.996
Rv0640rplK0.996
Rv0708rplP0.995
Rv0719rplF0.995
Rv1298rpmE0.995
Rv0701rplC0.995
Rv0702rplD0.995
Rv0723rplO0.995
Rv0704rplB0.994
Rv0704rplB0.994
Rv3442crpsI0.993
Rv0056rplI0.993
Rv2440cobg0.993
Rv0056rplI0.993
Rv2440cobg0.993
Rv1643rplT0.993
Rv2440cobg0.993
Rv3458crpsD0.992
Rv0714rplN0.992
Rv3458crpsD0.992
Rv0652rplL0.991
Rv0706rplV0.991
Rv0716rplE0.991
Rv0716rplE0.991
Rv3456crplQ0.99
Rv1015crplY0.988
Rv1015crplY0.988
Rv2057crpmG10.986
Rv0720rplR0.985
Rv0715rplX0.985
Rv0651rplJ0.983
Rv3459crpsK0.982
Rv0703rplW0.981
Rv3460crpsM0.98
Rv0721rpsE0.977
Rv0721rpsE0.977
Rv0707rpsC0.975
Rv0707rpsC0.975
Rv2882cfrr0.971
Rv2412rpsT0.97
Rv0683rpsG0.967
Rv0722rpmD0.964
Rv2785crpsO0.963
Rv0705rpsS0.96
Rv2906ctrmD0.959
Rv0700rpsJ0.959
Rv0053rpsF0.956
Rv0718rpsH0.955
Rv1630rpsA0.954
Rv2909crpsP0.954
Rv0055rpsR10.953
Rv1308atpA0.95
Rv1308atpA0.95
Rv1308atpA0.95
Rv2890crpsB0.944
Rv0684fusA10.941
Rv0684fusA10.941
Rv0684fusA10.941
Rv3924crpmH0.941
Rv0684fusA10.941
Rv0684fusA10.941
Rv0667rpoB0.94
Rv0667rpoB0.94
Rv0667rpoB0.94
Rv0667rpoB0.94
Rv0667rpoB0.94
Rv0667rpoB0.94
Rv0634BrpmG20.939
Rv3457crpoA0.935
Rv3457crpoA0.935
Rv3457crpoA0.935
Rv2439cproB0.932
Rv2439cproB0.932
Rv2058crpmB20.931
Rv1641infC0.925
Rv1641infC0.925
Rv2889ctsf0.921
Rv2889ctsf0.921
Rv2448cvalS0.916
Rv2448cvalS0.916
Rv2448cvalS0.916
Rv2462ctig0.913
Rv2462ctig0.913
Rv2462ctig0.913
Rv2343cdnaG0.911
Rv2343cdnaG0.911
Rv2343cdnaG0.911
Rv2343cdnaG0.911
Rv2343cdnaG0.911
Rv0682rpsL0.909
Rv2572caspS0.907
Rv2572caspS0.907
Rv2572caspS0.907
Rv0710rpsQ0.904
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.79824.305
zincPubChem0.79865.409
threo-1,4-dimercapto-2,3-butanediolPubChem0.708154.251
dithiothreitolPubChem0.708154.251
telithromycinPubChem0.708812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.708812.004
bryamycinPubChem0.7041664.89
nchembio.341-comp1PubChem0.7041664.89