Rv0719

Tuberculist information
Gene namerplF
Protein function50S ribosomal protein L6 RplF
Functional category(tuberculist)information pathways
Gene location(kb)813.398
Molecular mass(da)19377.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 179
	  		  	1    MSRIGKQPIPVPAGVDVTIEGQSISVKGPKGTLGLTVAEPIKVARNDDGAIVVTRPDDER   60
			  	61   RNRSLHGLSRTLVSNLVTGVTQGYTTKMEIFGVGYRVQLKGSNLEFALGYSHPVVIEAPE  120
			  	121  GITFAVQAPTKFTVSGIDKQKVGQIAANIRRLRRPDPYKGKGVRYEGEQIRRKVGKTGK

Known structures in the PDB
No Known structures
1 18 35 52 69 86 103 120 137 154 171 Range: 11 to 83  |  Coverage: 40% Ribosomal_L6 Range: 91 to 166  |  Coverage: 41% Ribosomal_L6 Range: 8 to 171  |  Coverage: 91% 1 Range: 80 to 178  |  Coverage: 54% 1
Number of amino acids : 179
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L6PF0034711-83
Ribosomal_L6PF0034791-166
Mtb Structural Proteome models
Model Number1
Model nameRv0719
Template1RL6    APDBCREDO
Template coverage7_169
Template Identity(%)51.5
Model coverage(%)91.1
Normalized DOPE score-1.193

Structure Models from Chopin
Model Number1
Profile3.90.930.12
Click for model details
zscore16.86
Residue begin80
Residue end178
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0719Gene nameConfidence Score
Rv0721rpsE0.999
Rv0702rplD0.999
Rv0716rplE0.999
Rv0722rpmD0.999
Rv0716rplE0.999
Rv0708rplP0.999
Rv0723rplO0.999
Rv0704rplB0.999
Rv0704rplB0.999
Rv0718rpsH0.999
Rv0640rplK0.999
Rv0720rplR0.999
Rv0714rplN0.999
Rv0640rplK0.999
Rv0706rplV0.999
Rv0721rpsE0.999
Rv0701rplC0.999
Rv0715rplX0.999
Rv0641rplA0.999
Rv3443crplM0.999
Rv0651rplJ0.998
Rv0703rplW0.998
Rv0652rplL0.998
Rv3456crplQ0.998
Rv0684fusA10.997
Rv0717rpsN10.997
Rv3460crpsM0.997
Rv0709rpmC0.997
Rv0684fusA10.997
Rv0684fusA10.997
Rv0684fusA10.997
Rv0684fusA10.997
Rv0056rplI0.996
Rv3459crpsK0.996
Rv0056rplI0.996
Rv1643rplT0.996
Rv2890crpsB0.996
Rv0710rpsQ0.996
Rv0700rpsJ0.996
Rv2442crplU0.996
Rv3442crpsI0.996
Rv0707rpsC0.995
Rv2441crpmA0.995
Rv0705rpsS0.995
Rv0707rpsC0.995
Rv3458crpsD0.993
Rv0682rpsL0.993
Rv3457crpoA0.993
Rv3457crpoA0.993
Rv2904crplS0.993
Rv3457crpoA0.993
Rv3458crpsD0.993
Rv0683rpsG0.992
Rv0732secY0.991
Rv2056crpsN20.991
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv3462cinfA0.988
Rv2889ctsf0.987
Rv2889ctsf0.987
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv0685tuf0.983
Rv0685tuf0.983
Rv0685tuf0.983
Rv0639nusG0.981
Rv0639nusG0.981
Rv0120cfusA20.975
Rv0120cfusA20.975
Rv0120cfusA20.975
Rv0120cfusA20.975
Rv0734mapA0.975
Rv0120cfusA20.975
Rv2057crpmG10.974
Rv2882cfrr0.972
Rv1298rpmE0.972
Rv2861cmapB0.968
Rv1015crplY0.966
Rv1015crplY0.966
Rv0634BrpmG20.959
Rv3461crpmJ0.958
Rv0733adk0.958
Rv0053rpsF0.958
Rv2839cinfB0.952
Rv2839cinfB0.952
Rv2839cinfB0.952
Rv2839cinfB0.952
Rv1023eno0.951
Rv1023eno0.951
Rv1641infC0.949
Rv1641infC0.949
Rv3924crpmH0.947
Rv2906ctrmD0.946
Rv3455ctruA0.943
Rv2785crpsO0.941
Rv2412rpsT0.926
Rv2793ctruB0.925
Rv2793ctruB0.925
Rv2916cffh0.923
Rv2916cffh0.923
Rv2916cffh0.923
Rv1308atpA0.922
Rv1308atpA0.922
Rv1308atpA0.922
Rv2572caspS0.915
Rv2572caspS0.915
Rv2572caspS0.915
Rv2448cvalS0.913
Rv2448cvalS0.913
Rv2448cvalS0.913
Rv2909crpsP0.912
Rv2058crpmB20.91
Rv1699pyrG0.903
Rv2992cgltS0.903
Rv1699pyrG0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.79924.305
zincPubChem0.79865.409
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.708812.004
telithromycinPubChem0.708812.004
bryamycinPubChem0.7061664.89
nchembio.341-comp1PubChem0.7061664.89