Rv1015c

Tuberculist information
Gene namerplY
Protein function50S ribosomal protein L25 RplY
Functional category(tuberculist)information pathways
Gene location(kb)1133.92
Molecular mass(da)22441.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 215
	  		  	1    MAKSASNQLRVTVRTETGKGASRRARRAGKIPAVLYGHGAEPQHLELPGHDYAAVLRHSG   60
			  	61   TNAVLTLDIAGKEQLALTKALHIHPIRRTIQHADLLVVRRGEKVVVEVSVVVEGQAGPDT  120
			  	121  LVTQETNSIEIEAEALSIPEQLTVSIEGAEPGTQLTAGQIALPAGVSLISDPDLLVVNVV  180
			  	181  KAPTAEELEGEVAGAEEAEEAAVEAGEAEAAGESE

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 9 to 95  |  Coverage: 40% Ribosomal_L25p Range: 102 to 187  |  Coverage: 39% Ribosomal_TL5_C Range: 7 to 190  |  Coverage: 85% 1 Range: 98 to 188  |  Coverage: 41% 1 Range: 1 to 113  |  Coverage: 52% 2
Number of amino acids : 215
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L25pPF013869-95
Ribosomal_TL5_CPF14693102-187
Mtb Structural Proteome models
Model Number1
Model nameRv1015c
Template1FEU    APDBCREDO
Template coverage3_185
Template Identity(%)24.6
Model coverage(%)85.1
Normalized DOPE score-0.026

Structure Models from Chopin
Model Number1
Profile2.170.120.20
Click for model details
zscore19.27
Residue begin98
Residue end188
Model Number2
Profileb.53.1.1 - 2.40.240.10
Click for model details
zscore9.71
Residue begin1
Residue end113
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1015cGene nameConfidence Score
Rv0056rplI0.993
Rv0056rplI0.993
Rv1014cpth0.988
Rv2441crpmA0.988
Rv1643rplT0.985
Rv2904crplS0.985
Rv2442crplU0.984
Rv0053rpsF0.984
Rv0652rplL0.983
Rv3456crplQ0.983
Rv0715rplX0.98
Rv0708rplP0.98
Rv1017cprsA0.978
Rv1017cprsA0.978
Rv3443crplM0.975
Rv0720rplR0.975
Rv0641rplA0.97
Rv0640rplK0.969
Rv0640rplK0.969
Rv0714rplN0.968
Rv0706rplV0.968
Rv0719rplF0.966
Rv0716rplE0.964
Rv0716rplE0.964
Rv1298rpmE0.964
Rv0702rplD0.964
Rv0651rplJ0.962
Rv0701rplC0.958
Rv0704rplB0.957
Rv0704rplB0.957
Rv0703rplW0.953
Rv0723rplO0.949
Rv0055rpsR10.938
Rv2462ctig0.931
Rv2462ctig0.931
Rv2462ctig0.931
Rv2909crpsP0.929
Rv1018cglmU0.927
Rv1018cglmU0.927
Rv0710rpsQ0.918
Rv2890crpsB0.916
Rv0634BrpmG20.914
Rv0683rpsG0.912
Rv2889ctsf0.91
Rv2889ctsf0.91
Rv0682rpsL0.908
Rv2534cefp0.901
Rv2534cefp0.901
Rv2534cefp0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.76665.409
magnesiumPubChem0.76524.305
Coomassie bluePubChem0.733695.584