Rv0720

Tuberculist information
Gene namerplR
Protein function50S ribosomal protein L18 RplR
Functional category(tuberculist)information pathways
Gene location(kb)813.94
Molecular mass(da)13184.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 122
	  		  	1    MAQSVSATRRISRLRRHTRLRKKLSGTAERPRLVVHRSARHIHVQLVNDLNGTTVAAASS   60
			  	61   IEADVRGVPGDKKARSVRVGQLIAERAKAAGIDTVVFDRGGYTYGGRIAALADAARENGL  120
			  	121  SF

Known structures in the PDB
No Known structures
1 13 25 37 49 61 73 85 97 109 121 Range: 8 to 122  |  Coverage: 93% Ribosomal_L18p Range: 30 to 122  |  Coverage: 75% 1 Range: 1 to 122  |  Coverage: 99% 1
Number of amino acids : 122
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L18pPF008618-122
Mtb Structural Proteome models
Model Number1
Model nameRv0720
Template1ILY    APDBCREDO
Template coverage22_111
Template Identity(%)47.8
Model coverage(%)75.4
Normalized DOPE score-0.604

Structure Models from Chopin
Model Number1
Profilec.55.4.1 - 3.30.420.100
Click for model details
zscore18.87
Residue begin1
Residue end122
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0720Gene nameConfidence Score
Rv0719rplF0.999
Rv0714rplN0.999
Rv0721rpsE0.999
Rv0715rplX0.999
Rv0721rpsE0.999
Rv0716rplE0.999
Rv0722rpmD0.999
Rv0716rplE0.999
Rv0723rplO0.999
Rv0718rpsH0.999
Rv0706rplV0.998
Rv0701rplC0.998
Rv0641rplA0.998
Rv0702rplD0.998
Rv3456crplQ0.998
Rv0703rplW0.998
Rv0652rplL0.998
Rv0708rplP0.998
Rv0704rplB0.998
Rv0704rplB0.998
Rv0640rplK0.997
Rv3443crplM0.997
Rv0640rplK0.997
Rv0651rplJ0.997
Rv0709rpmC0.997
Rv0705rpsS0.995
Rv2904crplS0.995
Rv0056rplI0.994
Rv2442crplU0.994
Rv0056rplI0.994
Rv3460crpsM0.994
Rv0717rpsN10.994
Rv0684fusA10.993
Rv0684fusA10.993
Rv0684fusA10.993
Rv3459crpsK0.993
Rv0684fusA10.993
Rv0684fusA10.993
Rv0710rpsQ0.993
Rv0700rpsJ0.992
Rv3458crpsD0.992
Rv3458crpsD0.992
Rv3457crpoA0.992
Rv3457crpoA0.992
Rv3457crpoA0.992
Rv0707rpsC0.991
Rv0707rpsC0.991
Rv0682rpsL0.991
Rv0732secY0.991
Rv0683rpsG0.99
Rv3442crpsI0.987
Rv0685tuf0.987
Rv0685tuf0.987
Rv0685tuf0.987
Rv1643rplT0.986
Rv2441crpmA0.985
Rv2056crpsN20.984
Rv3462cinfA0.983
Rv0734mapA0.981
Rv0668rpoC0.98
Rv0668rpoC0.98
Rv0668rpoC0.98
Rv0668rpoC0.98
Rv0668rpoC0.98
Rv2057crpmG10.979
Rv2861cmapB0.976
Rv1015crplY0.975
Rv1015crplY0.975
Rv1298rpmE0.974
Rv3461crpmJ0.974
Rv2890crpsB0.964
Rv0053rpsF0.964
Rv0667rpoB0.96
Rv0667rpoB0.96
Rv0667rpoB0.96
Rv0667rpoB0.96
Rv2889ctsf0.96
Rv2889ctsf0.96
Rv0667rpoB0.96
Rv0667rpoB0.96
Rv2882cfrr0.957
Rv2785crpsO0.957
Rv2839cinfB0.954
Rv2839cinfB0.954
Rv2839cinfB0.954
Rv2839cinfB0.954
Rv0733adk0.946
Rv3924crpmH0.946
Rv1641infC0.941
Rv1641infC0.941
Rv3455ctruA0.933
Rv2916cffh0.932
Rv0634BrpmG20.932
Rv2916cffh0.932
Rv2916cffh0.932
Rv2906ctrmD0.931
Rv2058crpmB20.918
Rv0639nusG0.915
Rv0639nusG0.915
Rv0055rpsR10.911
Rv1308atpA0.906
Rv1308atpA0.906
Rv1308atpA0.906
Rv2909crpsP0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.81124.305
zincPubChem0.79865.409