Rv0708

Tuberculist information
Gene namerplP
Protein function50S ribosomal protein L16 RplP
Functional category(tuberculist)information pathways
Gene location(kb)805.11
Molecular mass(da)15692.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 138
	  		  	1    MLIPRKVKHRKQHHPRQRGIASGGTTVNFGDYGIQALEHAYVTNRQIESARIAINRHIKR   60
			  	61   GGKVWINIFPDRPLTKKPAETRMGSGKGSPEWWVANVKPGRVLFELSYPNEGVARAALTR  120
			  	121  AIHKLPIKARIITREEQF

Known structures in the PDB
No Known structures
1 14 27 40 53 66 79 92 105 118 131 Range: 4 to 133  |  Coverage: 93% Ribosomal_L16 Range: 1 to 135  |  Coverage: 97% 1 Range: 1 to 138  |  Coverage: 99% 1
Number of amino acids : 138
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L16PF002524-133
Mtb Structural Proteome models
Model Number1
Model nameRv0708
Template1WKI    APDBCREDO
Template coverage1_135
Template Identity(%)56.3
Model coverage(%)97.1
Normalized DOPE score0.041

Structure Models from Chopin
Model Number1
Profiled.41.4.2 - 3.90.1170.10
Click for model details
zscore29.2
Residue begin1
Residue end138
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0708Gene nameConfidence Score
Rv0710rpsQ0.999
Rv0704rplB0.999
Rv0719rplF0.999
Rv0714rplN0.999
Rv0705rpsS0.999
Rv0640rplK0.999
Rv0706rplV0.999
Rv0640rplK0.999
Rv0701rplC0.999
Rv0716rplE0.999
Rv0707rpsC0.999
Rv0702rplD0.999
Rv0716rplE0.999
Rv3456crplQ0.999
Rv0707rpsC0.999
Rv0703rplW0.999
Rv0709rpmC0.999
Rv0704rplB0.999
Rv0720rplR0.998
Rv0715rplX0.998
Rv3443crplM0.998
Rv0641rplA0.998
Rv3459crpsK0.998
Rv0652rplL0.998
Rv0723rplO0.998
Rv0700rpsJ0.997
Rv0721rpsE0.997
Rv0721rpsE0.997
Rv0651rplJ0.997
Rv1643rplT0.997
Rv0682rpsL0.996
Rv0722rpmD0.996
Rv3460crpsM0.996
Rv0684fusA10.995
Rv3457crpoA0.995
Rv0684fusA10.995
Rv3442crpsI0.995
Rv2904crplS0.995
Rv3458crpsD0.995
Rv0684fusA10.995
Rv2441crpmA0.995
Rv3458crpsD0.995
Rv0684fusA10.995
Rv0684fusA10.995
Rv3457crpoA0.995
Rv0718rpsH0.995
Rv3457crpoA0.995
Rv0717rpsN10.994
Rv0056rplI0.992
Rv0056rplI0.992
Rv0732secY0.991
Rv0639nusG0.991
Rv2442crplU0.991
Rv0639nusG0.991
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0668rpoC0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0683rpsG0.99
Rv2056crpsN20.99
Rv0668rpoC0.99
Rv0634BrpmG20.988
Rv0685tuf0.987
Rv0685tuf0.987
Rv0685tuf0.987
Rv2890crpsB0.985
Rv0734mapA0.984
Rv2889ctsf0.984
Rv2889ctsf0.984
Rv2882cfrr0.983
Rv2057crpmG10.981
Rv3462cinfA0.98
Rv1015crplY0.98
Rv1015crplY0.98
Rv1298rpmE0.98
Rv3461crpmJ0.979
Rv2861cmapB0.977
Rv2058crpmB20.967
Rv0053rpsF0.965
Rv1641infC0.961
Rv1641infC0.961
Rv3924crpmH0.951
Rv0120cfusA20.95
Rv0120cfusA20.95
Rv0120cfusA20.95
Rv0120cfusA20.95
Rv0120cfusA20.95
Rv2785crpsO0.949
Rv2906ctrmD0.946
Rv0733adk0.942
Rv3455ctruA0.934
Rv1308atpA0.933
Rv1308atpA0.933
Rv2909crpsP0.933
Rv1308atpA0.933
Rv0055rpsR10.932
Rv0350dnaK0.916
Rv2839cinfB0.912
Rv2916cffh0.912
Rv2839cinfB0.912
Rv2839cinfB0.912
Rv2916cffh0.912
Rv2839cinfB0.912
Rv2916cffh0.912
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
DrugBank IDDrug Name
DB00446DrugBankChloramphenicol
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.79865.409
magnesiumPubChem0.79824.305
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.708812.004
telithromycinPubChem0.708812.004
bryamycinPubChem0.7051664.89
nchembio.341-comp1PubChem0.7051664.89
PPUPubChem0.705551.489