SInCRe - Rv0350

Tuberculist information

Gene name	dnaK
Protein function	Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa protein) (HSP70)
Functional category(tuberculist)	virulence,detoxification and adaptaion
Gene location(kb)	419.835
Molecular mass(da)	66830.9
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 625

	  		  	1    MARAVGIDLGTTNSVVSVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVT   60
			  	61   NVDRTVRSVKRHMGSDWSIEIDGKKYTAPEISARILMKLKRDAEAYLGEDITDAVITTPA  120
			  	121  YFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQRILVFDLGGGTFDVSL  180
			  	181  LEIGEGVVEVRATSGDNHLGGDDWDQRVVDWLVDKFKGTSGIDLTKDKMAMQRLREAAEK  240
			  	241  AKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRKPFQSVIADT  300
			  	301  GISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEV  360
			  	361  KDVLLLDVTPLSLGIETKGGVMTRLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGERE  420
			  	421  IAAHNKLLGSFELTGIPPAPRGIPQIEVTFDIDANGIVHVTAKDKGTGKENTIRIQEGSG  480
			  	481  LSKEDIDRMIKDAEAHAEEDRKRREEADVRNQAETLVYQTEKFVKEQREAEGGSKVPEDT  540
			  	541  LNKVDAAVAEAKAALGGSDISAIKSAMEKLGQESQALGQAIYEAAQAASQATGAAHPGGE  600
			  	601  PGGAHPGSADDVVDAEVVDDGREAK

Known structures in the PDB

No Known structures

Number of amino acids : 625

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
HSP70	PF00012	4-83
HSP70	PF00012	78-583

Mtb Structural Proteome models

Model Number	1
Model name	Rv0350.3
Template	1DKX APDB CREDO
Template coverage	389_606
Template Identity(%)	55.5
Model coverage(%)	35.5
Normalized DOPE score	-0.89

Model Number	2
Model name	Rv0350.4
Template	1U00 APDB CREDO
Template coverage	390_615
Template Identity(%)	34.1
Model coverage(%)	36.8
Normalized DOPE score	-0.815

Model Number	3
Model name	Rv0350
Template	1YUW APDB CREDO
Template coverage	4_554
Template Identity(%)	54.2
Model coverage(%)	83.7
Normalized DOPE score	-0.361

Structure Models from Chopin

CHOPIN models not available for this query

Binding pockets

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv0350	Gene name	Confidence Score
Rv0351	grpE	0.999
Rv2374c	hrcA	0.999
Rv0352	dnaJ1	0.999
Rv2374c	hrcA	0.999
Rv0352	dnaJ1	0.999
Rv0352	dnaJ1	0.999
Rv2373c	dnaJ2	0.998
Rv0384c	clpB	0.998
Rv2373c	dnaJ2	0.998
Rv0384c	clpB	0.998
Rv0384c	clpB	0.998
Rv0384c	clpB	0.998
Rv2373c	dnaJ2	0.998
Rv0440	groEL2	0.997
Rv3596c	clpC1	0.996
Rv3596c	clpC1	0.996
Rv3417c	groEL1	0.996
Rv3596c	clpC1	0.996
Rv3596c	clpC1	0.996
Rv3596c	clpC1	0.996
Rv3418c	groES	0.995
Rv2299c	htpG	0.995
Rv2299c	htpG	0.995
Rv2031c	hspX	0.991
Rv0353	hspR	0.988
Rv1436	gap	0.985
Rv1436	gap	0.985
Rv1437	pgk	0.984
Rv0685	tuf	0.98
Rv0685	tuf	0.98
Rv0685	tuf	0.98
Rv1023	eno	0.974
Rv1023	eno	0.974
Rv2462c	tig	0.972
Rv2462c	tig	0.972
Rv2462c	tig	0.972
Rv2461c	clpP1	0.97
Rv2890c	rpsB	0.969
Rv3914	trxC	0.969
Rv0667	rpoB	0.966
Rv0667	rpoB	0.966
Rv0667	rpoB	0.966
Rv0667	rpoB	0.966
Rv0667	rpoB	0.966
Rv0667	rpoB	0.966
Rv1848	ureA	0.966
Rv0716	rplE	0.961
Rv3457c	rpoA	0.961
Rv3457c	rpoA	0.961
Rv0716	rplE	0.961
Rv3457c	rpoA	0.961
Rv0005	gyrB	0.956
Rv0005	gyrB	0.956
Rv0005	gyrB	0.956
Rv0005	gyrB	0.956
Rv1471	trxB1	0.955
Rv1223	htrA	0.954
Rv1223	htrA	0.954
Rv3025c	iscS	0.943
Rv2678c	hemE	0.942
Rv2889c	tsf	0.939
Rv0684	fusA1	0.939
Rv2889c	tsf	0.939
Rv0684	fusA1	0.939
Rv0684	fusA1	0.939
Rv0684	fusA1	0.939
Rv0684	fusA1	0.939
Rv2703	sigA	0.935
Rv2150c	ftsZ	0.935
Rv2703	sigA	0.935
Rv2150c	ftsZ	0.935
Rv2703	sigA	0.935
Rv1641	infC	0.935
Rv2703	sigA	0.935
Rv1641	infC	0.935
Rv1392	metK	0.934
Rv3846	sodA	0.934
Rv1131	prpC	0.934
Rv3610c	ftsH	0.934
Rv3610c	ftsH	0.934
Rv3610c	ftsH	0.934
Rv1392	metK	0.934
Rv1392	metK	0.934
Rv3846	sodA	0.934
Rv3336c	trpS	0.933
Rv1643	rplT	0.933
Rv0251c	hsp	0.932
Rv3443c	rplM	0.931
Rv2710	sigB	0.928
Rv2710	sigB	0.928
Rv2710	sigB	0.928
Rv2710	sigB	0.928
Rv3913	trxB2	0.927
Rv3913	trxB2	0.927
Rv3442c	rpsI	0.927
Rv0563	htpX	0.926
Rv0001	dnaA	0.925
Rv0001	dnaA	0.925
Rv1617	pykA	0.924
Rv0006	gyrA	0.924
Rv1617	pykA	0.924
Rv0006	gyrA	0.924
Rv2555c	alaS	0.921
Rv2457c	clpX	0.921
Rv2555c	alaS	0.921
Rv2457c	clpX	0.921
Rv2555c	alaS	0.921
Rv2457c	clpX	0.921
Rv2404c	lepA	0.92
Rv2404c	lepA	0.92
Rv3459c	rpsK	0.92
Rv2404c	lepA	0.92
Rv2404c	lepA	0.92
Rv2388c	hemN	0.917
Rv2388c	hemN	0.917
Rv0708	rplP	0.916
Rv2737c	recA	0.915
Rv2614c	thrS	0.915
Rv2737c	recA	0.915
Rv2614c	thrS	0.915
Rv2614c	thrS	0.915
Rv0704	rplB	0.914
Rv0704	rplB	0.914
Rv0721	rpsE	0.913
Rv0721	rpsE	0.913
Rv3628	ppa	0.912
Rv2783c	gpsI	0.911
Rv2783c	gpsI	0.911
Rv1630	rpsA	0.911
Rv2783c	gpsI	0.911
Rv2783c	gpsI	0.911
Rv2783c	gpsI	0.911
Rv0641	rplA	0.91
Rv2839c	infB	0.909
Rv2839c	infB	0.909
Rv2839c	infB	0.909
Rv2839c	infB	0.909
Rv2592c	ruvB	0.907
Rv2592c	ruvB	0.907
Rv1438	tpi	0.905
Rv0732	secY	0.904
Rv2916c	ffh	0.902
Rv0957	purH	0.902
Rv2916c	ffh	0.902
Rv0957	purH	0.902
Rv2916c	ffh	0.902

Potential ligand/drug binding sites

Protein Model	Pocket Number	Drug Binding Site	PMIN Score	Pvalue PMIN	PMAX Score	Pvalue PMAX
Rv0350.3	6	3uq6_ADN_B_401 PDB CREDO	0.647	0.128	0.647	0.001
Rv0350.4	6	2qak_1UN_A_1001 PDB CREDO	0.815	0.019	0.645	0.001
Rv0350.4	6	2q64_1UN_B_1001 PDB CREDO	0.815	0.020	0.645	0.001
Rv0350.4	6	2pyn_1UN_A_1001 PDB CREDO	0.813	0.020	0.643	0.001
Rv0350.4	6	1t7i_017_A_200 PDB CREDO	0.737	0.055	0.643	0.001
Rv0350.3	6	3uq6_ADN_A_401 PDB CREDO	0.642	0.132	0.642	0.001
Rv0350.4	6	2pym_1UN_A_1001 PDB CREDO	0.811	0.021	0.642	0.001
Rv0350.4	6	2q63_1UN_A_1001 PDB CREDO	0.807	0.022	0.639	0.001
Rv0350.4	6	1k6c_MK1_B_902 PDB CREDO	0.713	0.071	0.621	0.001
Rv0350.4	6	3el4_ROC_A_100 PDB CREDO	0.712	0.072	0.621	0.001
Rv0350.4	6	3oxc_ROC_A_401 PDB CREDO	0.642	0.132	0.615	0.002
Rv0350.4	6	3tl9_ROC_A_401 PDB CREDO	0.612	0.165	0.612	0.002
Rv0350.4	6	3cyx_ROC_A_201 PDB CREDO	0.654	0.120	0.612	0.002
Rv0350.4	6	1rl8_RIT_A_9001 PDB CREDO	0.744	0.051	0.603	0.002
Rv0350.4	6	2nnp_ROC_A_401 PDB CREDO	0.690	0.089	0.601	0.002
Rv0350.4	6	3ndu_ROC_D_100 PDB CREDO	0.643	0.132	0.601	0.002
Rv0350.4	6	3tkg_ROC_C_901 PDB CREDO	0.655	0.119	0.599	0.002
Rv0350.4	6	3k4v_ROC_D_201 PDB CREDO	0.667	0.108	0.595	0.002
Rv0350.3	6	2nnj_225_A_501 PDB CREDO	0.654	0.121	0.594	0.002
Rv0350.4	6	2nmy_ROC_A_401 PDB CREDO	0.621	0.155	0.593	0.002
Rv0350.4	6	2nnk_ROC_A_401 PDB CREDO	0.694	0.085	0.591	0.002
Rv0350.4	6	3d1x_ROC_A_201 PDB CREDO	0.616	0.160	0.590	0.003
Rv0350.4	4	1bx4_ADN_A_350 PDB CREDO	0.589	0.192	0.589	0.003
Rv0350.4	4	3ndv_AIC_B_376 PDB CREDO	0.645	0.130	0.589	0.003
Rv0350.4	6	3pwr_ROC_A_401 PDB CREDO	0.708	0.075	0.589	0.003
Rv0350.4	4	3ndv_AIC_D_374 PDB CREDO	0.644	0.131	0.588	0.003
Rv0350.4	6	3ndt_ROC_D_100 PDB CREDO	0.690	0.088	0.588	0.003
Rv0350.4	6	1hxb_ROC_A_100 PDB CREDO	0.742	0.052	0.587	0.003
Rv0350.3	6	3clb_TMQ_C_613 PDB CREDO	0.587	0.195	0.587	0.003
Rv0350.4	6	3ucb_017_A_201 PDB CREDO	0.689	0.090	0.586	0.003
Rv0350.4	6	3ogq_AB1_A_200 PDB CREDO	0.776	0.035	0.584	0.003
Rv0350.4	6	1c6z_ROC_B_505 PDB CREDO	0.737	0.055	0.583	0.003
Rv0350.4	6	2f80_017_B_301 PDB CREDO	0.736	0.056	0.583	0.003
Rv0350.3	5	1hwi_115_A_2 PDB CREDO	0.580	0.203	0.580	0.003
Rv0350.3	6	2itz_IRE_A_2021 PDB CREDO	0.785	0.031	0.579	0.003
Rv0350.3	6	3hbb_TMQ_A_611 PDB CREDO	0.577	0.208	0.577	0.003
Rv0350.4	6	3bvb_017_B_401 PDB CREDO	0.694	0.085	0.577	0.003
Rv0350.3	6	3ads_IMN_B_3 PDB CREDO	0.690	0.089	0.576	0.003
Rv0350.3	6	3grv_ADN_A_300 PDB CREDO	0.576	0.209	0.576	0.003
Rv0350.3	6	3r9c_ECL_A_451 PDB CREDO	0.702	0.079	0.576	0.003
Rv0350.4	4	1ict_T44_C_128 PDB CREDO	0.654	0.120	0.576	0.003
Rv0350.4	6	3sm2_478_A_126 PDB CREDO	0.746	0.050	0.575	0.003
Rv0350.4	6	3tkg_ROC_B_801 PDB CREDO	0.624	0.151	0.573	0.003
Rv0350.3	5	3tne_RIT_A_401 PDB CREDO	0.631	0.144	0.572	0.003
Rv0350.3	5	3tne_RIT_B_401 PDB CREDO	0.630	0.145	0.572	0.003
Rv0350.4	6	1xkk_FMM_A_91 PDB CREDO	0.778	0.034	0.570	0.004
Rv0350.4	4	2ceo_T44_A_1395 PDB CREDO	0.569	0.218	0.569	0.004
Rv0350.4	4	3ndv_AIC_A_375 PDB CREDO	0.651	0.123	0.568	0.004
Rv0350.4	4	2xrl_DXT_A_1211 PDB CREDO	0.593	0.187	0.568	0.004
Rv0350.3	5	3spk_TPV_A_100 PDB CREDO	0.587	0.195	0.568	0.004
Rv0350.4	4	2ydo_ADN_A_400 PDB CREDO	0.567	0.221	0.567	0.004
Rv0350.4	4	2riw_T44_A_1395 PDB CREDO	0.617	0.159	0.566	0.004
Rv0350.4	4	2ceo_T44_B_1395 PDB CREDO	0.565	0.223	0.565	0.004
Rv0350.4	4	3ndv_AIC_C_375 PDB CREDO	0.648	0.127	0.565	0.004
Rv0350.4	6	3gp0_NIL_A_1 PDB CREDO	0.791	0.028	0.565	0.004
Rv0350.4	6	3ufn_ROC_A_401 PDB CREDO	0.788	0.029	0.563	0.004
Rv0350.4	6	2aof_FRD_C_305 PDB CREDO	0.630	0.145	0.562	0.004
Rv0350.4	6	1n49_RIT_B_301 PDB CREDO	0.872	0.006	0.560	0.004
Rv0350.4	6	3k4v_ROC_B_201 PDB CREDO	0.622	0.153	0.559	0.004
Rv0350.3	5	1jg2_ADN_A_500 PDB CREDO	0.617	0.159	0.557	0.004
Rv0350.4	6	1c6y_MK1_B_524 PDB CREDO	0.818	0.018	0.555	0.005
Rv0350.3	6	2ity_IRE_A_2020 PDB CREDO	0.782	0.032	0.554	0.005
Rv0350.3	5	1hwi_115_D_3 PDB CREDO	0.610	0.167	0.554	0.005
Rv0350.3	5	2y6o_1N1_A_1892 PDB CREDO	0.590	0.191	0.553	0.005
Rv0350.4	6	3ndt_ROC_A_101 PDB CREDO	0.627	0.148	0.551	0.005
Rv0350.4	6	3el5_1UN_B_201 PDB CREDO	0.713	0.071	0.550	0.005
Rv0350.3	5	1hwi_115_B_1 PDB CREDO	0.605	0.173	0.549	0.005
Rv0350.3	6	3ug2_IRE_A_1 PDB CREDO	0.604	0.175	0.548	0.005
Rv0350.4	4	3uq6_ADN_B_401 PDB CREDO	0.627	0.148	0.547	0.005
Rv0350.4	4	2trt_TAC_A_222 PDB CREDO	0.646	0.128	0.546	0.005
Rv0350.3	6	1xbb_STI_A_1 PDB CREDO	0.601	0.178	0.546	0.005
Rv0350.3	6	1uay_ADN_A_1001 PDB CREDO	0.570	0.216	0.544	0.005
Rv0350.4	4	3upn_IM2_B_800 PDB CREDO	0.544	0.252	0.544	0.006
Rv0350.3	6	2bxf_DZP_A_2001 PDB CREDO	0.569	0.218	0.543	0.006
Rv0350.4	4	2o7o_DXT_A_222 PDB CREDO	0.643	0.132	0.543	0.006
Rv0350.4	4	2xn6_T44_A_1370 PDB CREDO	0.643	0.132	0.543	0.006
Rv0350.3	6	3jw5_TOP_A_208 PDB CREDO	0.661	0.114	0.543	0.006
Rv0350.4	4	2xn7_T44_A_1355 PDB CREDO	0.642	0.133	0.542	0.006
Rv0350.3	5	3ut5_LOC_D_502 PDB CREDO	0.597	0.183	0.542	0.006
Rv0350.3	6	3jw5_TOP_B_208 PDB CREDO	0.660	0.115	0.542	0.006
Rv0350.4	6	3ggu_017_B_201 PDB CREDO	0.738	0.055	0.541	0.006
Rv0350.4	6	1hxw_RIT_B_301 PDB CREDO	0.737	0.055	0.541	0.006
Rv0350.3	6	2eva_ADN_A_498 PDB CREDO	0.595	0.185	0.540	0.006
Rv0350.4	4	3mdv_CL6_A_506 PDB CREDO	0.590	0.191	0.539	0.006
Rv0350.3	6	2bxf_DZP_B_2001 PDB CREDO	0.564	0.225	0.538	0.006
Rv0350.3	6	1jg3_ADN_B_550 PDB CREDO	0.790	0.029	0.538	0.006
Rv0350.4	6	3ekq_ROC_A_100 PDB CREDO	0.811	0.021	0.535	0.006
Rv0350.3	6	1r9o_FLP_A_501 PDB CREDO	0.559	0.231	0.534	0.006
Rv0350.3	5	1hwk_117_D_3 PDB CREDO	0.626	0.150	0.534	0.006
Rv0350.4	6	3jvy_017_B_401 PDB CREDO	0.545	0.251	0.533	0.007
Rv0350.4	4	3ri5_IVM_E_349 PDB CREDO	0.656	0.119	0.533	0.007
Rv0350.4	4	3uq6_ADN_A_401 PDB CREDO	0.610	0.167	0.532	0.007
Rv0350.4	6	1n49_RIT_D_401 PDB CREDO	0.902	0.003	0.532	0.007
Rv0350.3	6	3ri5_IVM_E_349 PDB CREDO	0.751	0.047	0.532	0.007
Rv0350.3	5	1hwi_115_C_4 PDB CREDO	0.589	0.193	0.532	0.007
Rv0350.3	5	2ito_IRE_A_2020 PDB CREDO	0.705	0.077	0.531	0.007
Rv0350.4	4	2w9s_TOP_D_1158 PDB CREDO	0.579	0.205	0.531	0.007
Rv0350.3	5	1d4f_ADN_C_603 PDB CREDO	0.607	0.171	0.530	0.007
Rv0350.4	4	2pkm_ADN_A_501 PDB CREDO	0.554	0.239	0.529	0.007
Rv0350.4	4	3q1e_T44_D_328 PDB CREDO	0.553	0.240	0.529	0.007
Rv0350.3	5	1jg3_ADN_A_500 PDB CREDO	0.651	0.123	0.528	0.007
Rv0350.3	6	1lii_ADN_A_699 PDB CREDO	0.582	0.202	0.528	0.007
Rv0350.3	6	1bx4_ADN_A_350 PDB CREDO	0.605	0.173	0.528	0.007
Rv0350.4	4	1kvl_CLS_A_371 PDB CREDO	0.552	0.242	0.528	0.007
Rv0350.4	4	3ads_IMN_B_3 PDB CREDO	0.550	0.244	0.526	0.007
Rv0350.3	6	1rv7_AB1_B_1001 PDB CREDO	0.685	0.092	0.526	0.007
Rv0350.4	6	3lzv_017_A_200 PDB CREDO	0.843	0.012	0.526	0.007
Rv0350.3	5	2fum_MIX_D_3539 PDB CREDO	0.563	0.226	0.526	0.007
Rv0350.4	6	1hsh_MK1_A_401 PDB CREDO	0.776	0.035	0.526	0.007
Rv0350.4	4	3ubo_ADN_A_353 PDB CREDO	0.549	0.246	0.525	0.007
Rv0350.3	6	1lik_ADN_A_699 PDB CREDO	0.578	0.206	0.525	0.007
Rv0350.4	4	3sxr_1N1_B_2 PDB CREDO	0.620	0.156	0.524	0.008
Rv0350.3	5	1hwl_FBI_D_3 PDB CREDO	0.632	0.143	0.523	0.008
Rv0350.3	6	3clb_TMQ_D_614 PDB CREDO	0.523	0.284	0.523	0.008
Rv0350.4	6	3el0_1UN_A_201 PDB CREDO	0.837	0.013	0.523	0.008
Rv0350.4	4	2xn5_FUN_A_1356 PDB CREDO	0.618	0.158	0.522	0.008
Rv0350.3	5	1hwl_FBI_B_1 PDB CREDO	0.631	0.144	0.522	0.008
Rv0350.4	6	3qoz_017_A_201 PDB CREDO	0.546	0.249	0.522	0.008
Rv0350.3	6	3mdv_CL6_A_506 PDB CREDO	0.547	0.248	0.522	0.008
Rv0350.3	6	1m17_AQ4_A_999 PDB CREDO	0.680	0.097	0.522	0.008
Rv0350.4	4	4e3a_ADN_A_500 PDB CREDO	0.593	0.187	0.522	0.008
Rv0350.3	6	3clb_TMQ_B_612 PDB CREDO	0.546	0.250	0.521	0.008
Rv0350.4	6	1t46_STI_A_3 PDB CREDO	0.748	0.049	0.521	0.008
Rv0350.4	4	1ict_T44_D_129 PDB CREDO	0.641	0.134	0.520	0.008
Rv0350.3	5	3tkd_CYZ_A_266 PDB CREDO	0.572	0.214	0.519	0.008
Rv0350.4	4	3ubo_ADN_B_353 PDB CREDO	0.542	0.255	0.519	0.008
Rv0350.3	6	3ri5_IVM_A_349 PDB CREDO	0.792	0.028	0.519	0.008
Rv0350.4	4	2itz_IRE_A_2021 PDB CREDO	0.614	0.163	0.518	0.008
Rv0350.3	6	3hbb_TMQ_D_614 PDB CREDO	0.518	0.290	0.518	0.008
Rv0350.4	6	2ien_017_B_402 PDB CREDO	0.530	0.273	0.518	0.008
Rv0350.4	4	2w9s_TOP_F_1159 PDB CREDO	0.541	0.256	0.518	0.008
Rv0350.3	5	1uwh_BAX_A_1723 PDB CREDO	0.607	0.171	0.517	0.008
Rv0350.3	6	2ito_IRE_A_2020 PDB CREDO	0.790	0.029	0.517	0.008
Rv0350.4	6	3d20_017_A_201 PDB CREDO	0.566	0.222	0.517	0.008
Rv0350.4	6	3ekx_1UN_B_201 PDB CREDO	0.687	0.091	0.517	0.008
Rv0350.3	6	1ie4_T44_A_128 PDB CREDO	0.673	0.103	0.517	0.008
Rv0350.3	5	3oht_1N1_B_1000 PDB CREDO	0.593	0.188	0.517	0.008
Rv0350.3	5	1uwh_BAX_B_1723 PDB CREDO	0.605	0.172	0.517	0.008
Rv0350.3	5	3bbt_FMM_D_91 PDB CREDO	0.552	0.241	0.516	0.009
Rv0350.4	6	2ieo_017_A_402 PDB CREDO	0.578	0.207	0.516	0.009
Rv0350.3	6	3rhw_IVM_A_348 PDB CREDO	0.786	0.030	0.515	0.009
Rv0350.3	6	3rhw_IVM_B_349 PDB CREDO	0.786	0.030	0.515	0.009
Rv0350.3	6	3ri5_IVM_B_349 PDB CREDO	0.786	0.030	0.515	0.009
Rv0350.3	6	3ria_IVM_E_349 PDB CREDO	0.786	0.030	0.515	0.009
Rv0350.3	4	3g1u_ADN_D_438 PDB CREDO	0.535	0.266	0.515	0.009
Rv0350.4	6	3d1y_ROC_A_201 PDB CREDO	0.634	0.140	0.515	0.009
Rv0350.3	5	1hwk_117_A_2 PDB CREDO	0.640	0.134	0.514	0.009
Rv0350.3	5	1hwk_117_C_4 PDB CREDO	0.640	0.134	0.514	0.009
Rv0350.4	4	2xpw_OTC_A_222 PDB CREDO	0.659	0.116	0.514	0.009
Rv0350.3	5	3ut5_LOC_B_502 PDB CREDO	0.603	0.176	0.514	0.009
Rv0350.3	5	1hwl_FBI_A_2 PDB CREDO	0.621	0.155	0.514	0.009
Rv0350.4	4	3f4x_KLT_A_300 PDB CREDO	0.683	0.094	0.513	0.009
Rv0350.3	5	3so9_017_A_100 PDB CREDO	0.601	0.178	0.513	0.009
Rv0350.4	4	2vke_TAC_A_222 PDB CREDO	0.657	0.118	0.513	0.009
Rv0350.4	6	3d1z_017_B_201 PDB CREDO	0.602	0.176	0.513	0.009
Rv0350.3	5	2ity_IRE_A_2020 PDB CREDO	0.736	0.056	0.513	0.009
Rv0350.4	6	2hs2_017_A_201 PDB CREDO	0.602	0.177	0.512	0.009
Rv0350.4	4	1lii_ADN_A_699 PDB CREDO	0.646	0.128	0.512	0.009
Rv0350.3	6	3rhw_IVM_B_348 PDB CREDO	0.781	0.033	0.512	0.009
Rv0350.3	6	3rif_IVM_E_402 PDB CREDO	0.781	0.033	0.512	0.009
Rv0350.3	5	1hwl_FBI_C_4 PDB CREDO	0.618	0.158	0.512	0.009
Rv0350.4	4	3adx_IMN_B_3 PDB CREDO	0.605	0.173	0.511	0.009
Rv0350.3	5	2itz_IRE_A_2021 PDB CREDO	0.763	0.041	0.511	0.009
Rv0350.4	6	1hsh_MK1_C_402 PDB CREDO	0.754	0.046	0.511	0.009
Rv0350.3	6	2w9h_TOP_A_1160 PDB CREDO	0.535	0.266	0.511	0.009
Rv0350.4	6	3ndu_ROC_A_101 PDB CREDO	0.629	0.146	0.510	0.009
Rv0350.3	6	3rhw_IVM_D_348 PDB CREDO	0.779	0.034	0.510	0.009
Rv0350.3	6	3ri5_IVM_D_349 PDB CREDO	0.779	0.034	0.510	0.009
Rv0350.3	6	3ria_IVM_A_348 PDB CREDO	0.779	0.034	0.510	0.009
Rv0350.3	6	3hbb_TMQ_C_613 PDB CREDO	0.585	0.198	0.510	0.009
Rv0350.3	4	3ond_ADN_A_506 PDB CREDO	0.573	0.213	0.510	0.009
Rv0350.4	6	1ohr_1UN_A_201 PDB CREDO	0.752	0.046	0.510	0.009
Rv0350.4	6	1sh9_RIT_B_301 PDB CREDO	0.752	0.047	0.510	0.009
Rv0350.3	5	1uwj_BAX_B_1723 PDB CREDO	0.634	0.141	0.509	0.009
Rv0350.3	6	3sxr_1N1_B_2 PDB CREDO	0.690	0.089	0.509	0.010
Rv0350.4	6	3jw2_017_A_401 PDB CREDO	0.597	0.183	0.508	0.010
Rv0350.3	4	2c49_ADN_A_1301 PDB CREDO	0.548	0.246	0.508	0.010
Rv0350.3	6	3adx_IMN_B_3 PDB CREDO	0.689	0.090	0.508	0.010
Rv0350.3	6	3rhw_IVM_D_349 PDB CREDO	0.774	0.035	0.507	0.010
Rv0350.3	6	3ria_IVM_E_348 PDB CREDO	0.774	0.035	0.507	0.010
Rv0350.3	5	1hwk_117_B_1 PDB CREDO	0.669	0.106	0.507	0.010
Rv0350.4	4	2ij7_TPF_F_2474 PDB CREDO	0.581	0.202	0.507	0.010
Rv0350.3	5	1ie4_T44_B_328 PDB CREDO	0.700	0.081	0.507	0.010
Rv0350.3	5	3n58_ADN_A_500 PDB CREDO	0.581	0.202	0.507	0.010
Rv0350.4	4	3mdz_EZL_A_264 PDB CREDO	0.529	0.273	0.507	0.010
Rv0350.3	6	3ria_IVM_C_350 PDB CREDO	0.773	0.036	0.507	0.010
Rv0350.4	6	3spk_TPV_B_100 PDB CREDO	0.884	0.005	0.506	0.010
Rv0350.3	6	1jg3_ADN_A_500 PDB CREDO	0.833	0.015	0.506	0.010
Rv0350.3	6	1wrk_TFP_A_202 PDB CREDO	0.530	0.272	0.506	0.010
Rv0350.4	4	1lik_ADN_A_699 PDB CREDO	0.639	0.135	0.506	0.010
Rv0350.3	6	1fb7_ROC_A_100 PDB CREDO	0.725	0.063	0.506	0.010
Rv0350.3	4	3ce6_ADN_C_500 PDB CREDO	0.506	0.309	0.506	0.010
Rv0350.4	4	2bxf_DZP_A_2001 PDB CREDO	0.553	0.240	0.505	0.010
Rv0350.4	4	3ri5_IVM_D_349 PDB CREDO	0.672	0.103	0.505	0.010
Rv0350.3	4	3g1u_ADN_C_438 PDB CREDO	0.505	0.311	0.505	0.010
Rv0350.4	4	1ll9_AXL_B_964 PDB CREDO	0.550	0.244	0.504	0.010
Rv0350.3	6	3clb_TMQ_A_611 PDB CREDO	0.578	0.206	0.504	0.010
Rv0350.3	5	3spk_TPV_B_100 PDB CREDO	0.646	0.128	0.504	0.010
Rv0350.3	6	3tbg_RTZ_B_1 PDB CREDO	0.504	0.312	0.504	0.010
Rv0350.3	5	3q70_RIT_A_2001 PDB CREDO	0.609	0.169	0.504	0.010
Rv0350.3	4	3ce6_ADN_A_500 PDB CREDO	0.504	0.312	0.504	0.010
Rv0350.3	4	3ce6_ADN_B_500 PDB CREDO	0.504	0.312	0.504	0.010
Rv0350.4	6	3nu5_478_B_401 PDB CREDO	0.538	0.261	0.504	0.010
Rv0350.3	4	3n58_ADN_A_500 PDB CREDO	0.562	0.228	0.504	0.010
Rv0350.4	4	3ri5_IVM_B_349 PDB CREDO	0.671	0.105	0.504	0.010
Rv0350.3	5	2a69_RPT_M_8002 PDB CREDO	0.520	0.287	0.503	0.010
Rv0350.3	5	1t7j_478_A_200 PDB CREDO	0.590	0.192	0.503	0.010
Rv0350.4	6	2avo_MK1_B_902 PDB CREDO	0.635	0.139	0.503	0.010
Rv0350.3	4	3ce6_ADN_D_500 PDB CREDO	0.502	0.315	0.502	0.011
Rv0350.4	4	2c49_ADN_A_1301 PDB CREDO	0.643	0.131	0.502	0.011
Rv0350.4	4	3rif_IVM_E_402 PDB CREDO	0.669	0.107	0.502	0.011
Rv0350.4	6	1sdt_MK1_B_902 PDB CREDO	0.604	0.174	0.502	0.011
Rv0350.4	6	2o4s_AB1_A_400 PDB CREDO	0.524	0.281	0.502	0.011
Rv0350.4	4	1jg3_ADN_B_550 PDB CREDO	0.643	0.132	0.502	0.011
Rv0350.4	4	3rhw_IVM_D_348 PDB CREDO	0.668	0.108	0.501	0.011
Rv0350.4	4	3rhw_IVM_D_349 PDB CREDO	0.668	0.108	0.501	0.011
Rv0350.4	4	3ria_IVM_C_350 PDB CREDO	0.668	0.108	0.501	0.011
Rv0350.4	6	3ndw_RIT_A_100 PDB CREDO	0.618	0.158	0.501	0.011
Rv0350.3	5	4eyb_0WO_A_303 PDB CREDO	0.575	0.211	0.501	0.011
Rv0350.4	6	2o4l_TPV_A_403 PDB CREDO	0.536	0.265	0.501	0.011

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
1-methyl-5-chloroindoline methylbromidePubChem	0.865	262.574
phosphatePubChem	0.862	96.9872
adenosine diphosphatePubChem	0.784	427.201
magnesiumPubChem	0.772	24.305
LVSPubChem	0.764	596.736
nine aminoPubChem	0.756	1269.5
hydron diphosphatePubChem	0.755	391.981
ethanolPubChem	0.739	46.0684
BAAPubChem	0.737	191.269
pyrrhocoricinPubChem	0.724	2543.83
NBDPubChem	0.718	754.556
sulfatePubChem	0.714	96.0626