Rv0563

Tuberculist information
Gene namehtpX
Protein functionProbable protease transmembrane protein heat shock protein HtpX
Functional category(tuberculist)virulence,detoxification and adaptaion
Gene location(kb)653.879
Molecular mass(da)30681.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 286
	  		  	1    MTWHPHANRLKTFLLLVGMSALIVAVGALFGRTALMLAALFAVGMNVYVYFNSDKLALRA   60
			  	61   MHAQPVSELQAPAMYRIVRELATSAHQPMPRLYISDTAAPNAFATGRNPRNAAVCCTTGI  120
			  	121  LRILNERELRAVLGHELSHVYNRDILISCVAGALAAVITALANMAMWAGMFGGNRDNANP  180
			  	181  FALLLVALLGPIAATVIRMAVSRSREYQADESGAVLTGDPLALASALRKISGGVQAAPLP  240
			  	241  PEPQLASQAHLMIANPFRAGERIGSLFSTHPPIEDRIRRLEAMARG

Known structures in the PDB
No Known structures
1 29 57 85 113 141 169 197 225 253 281 Range: 25 to 279  |  Coverage: 88% Peptidase_M48 Range: 56 to 154  |  Coverage: 34% 1
Number of amino acids : 286
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Peptidase_M48PF0143525-279
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profile3.30.2010.10
Click for model details
zscore29.03
Residue begin56
Residue end154
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0563Gene nameConfidence Score
Rv2299chtpG0.933
Rv2299chtpG0.933
Rv0350dnaK0.926
Rv0384cclpB0.918
Rv0384cclpB0.918
Rv0384cclpB0.918
Rv0384cclpB0.918
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions