Rv1643

Tuberculist information
Gene namerplT
Protein function50S ribosomal protein L20 RplT
Functional category(tuberculist)information pathways
Gene location(kb)1853.18
Molecular mass(da)14526.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 129
	  		  	1    MARVKRAVNAHKKRRSILKASRGYRGQRSRLYRKAKEQQLHSLNYAYRDRRARKGEFRKL   60
			  	61   WIARINAAARLNDITYNRLIQGLKAAGVEVDRKNLADIAISDPAAFTALVDVARAALPED  120
			  	121  VNAPSGEAA

Known structures in the PDB
No Known structures
1 13 25 37 49 61 73 85 97 109 121 Range: 2 to 109  |  Coverage: 82% Ribosomal_L20 Range: 2 to 117  |  Coverage: 89% 1 Range: 1 to 120  |  Coverage: 92% 1 Range: 52 to 120  |  Coverage: 52% 2
Number of amino acids : 129
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L20PF004532-109
Mtb Structural Proteome models
Model Number1
Model nameRv1643
Template2AW4    QPDBCREDO
Template coverage1_116
Template Identity(%)60.3
Model coverage(%)88.5
Normalized DOPE score0.811

Structure Models from Chopin
Model Number1
Profilea.144.2.1 - 1.10.1900.20
Click for model details
zscore30.52
Residue begin1
Residue end120
Model Number2
Profile1.10.1900.20
Click for model details
zscore17.56
Residue begin52
Residue end120
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1643Gene nameConfidence Score
Rv2904crplS0.998
Rv0702rplD0.997
Rv0708rplP0.997
Rv1641infC0.997
Rv1641infC0.997
Rv3443crplM0.996
Rv0056rplI0.996
Rv0719rplF0.996
Rv0056rplI0.996
Rv3456crplQ0.995
Rv0641rplA0.994
Rv0704rplB0.994
Rv0704rplB0.994
Rv0640rplK0.993
Rv2441crpmA0.993
Rv0640rplK0.993
Rv0701rplC0.993
Rv2890crpsB0.991
Rv0714rplN0.99
Rv1642rpmI0.99
Rv0652rplL0.989
Rv0706rplV0.989
Rv0716rplE0.988
Rv0716rplE0.988
Rv0723rplO0.987
Rv0720rplR0.986
Rv1015crplY0.985
Rv1015crplY0.985
Rv2442crplU0.984
Rv1298rpmE0.981
Rv2889ctsf0.979
Rv0703rplW0.979
Rv2889ctsf0.979
Rv0715rplX0.979
Rv3442crpsI0.978
Rv0651rplJ0.978
Rv2882cfrr0.978
Rv0684fusA10.977
Rv0684fusA10.977
Rv0684fusA10.977
Rv2057crpmG10.977
Rv0684fusA10.977
Rv0684fusA10.977
Rv3460crpsM0.975
Rv0707rpsC0.974
Rv0707rpsC0.974
Rv0721rpsE0.972
Rv0721rpsE0.972
Rv3459crpsK0.971
Rv1649pheS0.969
Rv1649pheS0.969
Rv3924crpmH0.968
Rv1017cprsA0.964
Rv1017cprsA0.964
Rv2614cthrS0.962
Rv2614cthrS0.962
Rv2614cthrS0.962
Rv0700rpsJ0.962
Rv2785crpsO0.955
Rv3458crpsD0.954
Rv3458crpsD0.954
Rv0053rpsF0.951
Rv0055rpsR10.951
Rv1644tsnR0.948
Rv1644tsnR0.948
Rv2909crpsP0.948
Rv0705rpsS0.944
Rv2916cffh0.943
Rv2916cffh0.943
Rv2916cffh0.943
Rv3457crpoA0.942
Rv3457crpoA0.942
Rv3457crpoA0.942
Rv0634BrpmG20.939
Rv0710rpsQ0.937
Rv0718rpsH0.936
Rv0722rpmD0.935
Rv0683rpsG0.935
Rv0350dnaK0.933
Rv2412rpsT0.932
Rv0682rpsL0.931
Rv1406fmt0.927
Rv1406fmt0.927
Rv0709rpmC0.926
Rv2058crpmB20.926
Rv3461crpmJ0.909
Rv1650pheT0.902
Rv1650pheT0.902
Rv1650pheT0.902
Rv1650pheT0.902
Rv0120cfusA20.901
Rv0120cfusA20.901
Rv0120cfusA20.901
Rv0120cfusA20.901
Rv0120cfusA20.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.79824.305
zincPubChem0.79865.409
selenomethioninePubChem0.71196.106
hydron sulfatePubChem0.71196.157
sulfatePubChem0.7196.0626
SeMetPubChem0.71196.106
telithromycinPubChem0.705812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.705812.004
bryamycinPubChem0.7011664.89
nchembio.341-comp1PubChem0.7011664.89