Rv0702

Tuberculist information
Gene namerplD
Protein function50S ribosomal protein L4 RplD
Functional category(tuberculist)information pathways
Gene location(kb)801.462
Molecular mass(da)23742.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 223
	  		  	1    MAAQEQKTLKIDVKTPAGKVDGAIELPAELFDVPANIALMHQVVTAQRAAARQGTHSTKT   60
			  	61   RGEVSGGGRKPYRQKGTGRARQGSTRAPQFTGGGVVHGPKPRDYSQRTPKKMIAAALRGA  120
			  	121  LSDRARNGRIHAITELVEGQNPSTKSARAFLASLTERKQVLVVIGRSDEAGAKSVRNLPG  180
			  	181  VHILAPDQLNTYDVLRADDVVFSVEALNAYIAANTTTSEEVSA

Known structures in the PDB
No Known structures
1 23 45 67 89 111 133 155 177 199 221 Range: 24 to 212  |  Coverage: 84% Ribosomal_L4 Range: 9 to 212  |  Coverage: 91% 1 Range: 1 to 217  |  Coverage: 96% 1
Number of amino acids : 223
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L4PF0057324-212
Mtb Structural Proteome models
Model Number1
Model nameRv0702
Template2AW4    EPDBCREDO
Template coverage1_198
Template Identity(%)35.9
Model coverage(%)91.0
Normalized DOPE score1.351

Structure Models from Chopin
Model Number1
Profilec.22.1.1 - 3.40.1370.10
Click for model details
zscore25.68
Residue begin1
Residue end217
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0702Gene nameConfidence Score
Rv0719rplF0.999
Rv0714rplN0.999
Rv0640rplK0.999
Rv0706rplV0.999
Rv0700rpsJ0.999
Rv0640rplK0.999
Rv0707rpsC0.999
Rv0701rplC0.999
Rv0716rplE0.999
Rv0641rplA0.999
Rv0707rpsC0.999
Rv0703rplW0.999
Rv3443crplM0.999
Rv0716rplE0.999
Rv0708rplP0.999
Rv0704rplB0.999
Rv0723rplO0.999
Rv0704rplB0.999
Rv0705rpsS0.999
Rv0720rplR0.998
Rv0715rplX0.998
Rv0652rplL0.998
Rv3456crplQ0.998
Rv0684fusA10.997
Rv0684fusA10.997
Rv0721rpsE0.997
Rv0684fusA10.997
Rv0721rpsE0.997
Rv0684fusA10.997
Rv0651rplJ0.997
Rv1643rplT0.997
Rv0709rpmC0.997
Rv3460crpsM0.997
Rv0684fusA10.997
Rv3442crpsI0.996
Rv3459crpsK0.996
Rv0718rpsH0.996
Rv0710rpsQ0.996
Rv2441crpmA0.995
Rv3458crpsD0.995
Rv3458crpsD0.995
Rv2904crplS0.994
Rv2442crplU0.993
Rv0683rpsG0.993
Rv0667rpoB0.992
Rv3457crpoA0.992
Rv0667rpoB0.992
Rv3457crpoA0.992
Rv0667rpoB0.992
Rv0667rpoB0.992
Rv0056rplI0.992
Rv0722rpmD0.992
Rv0667rpoB0.992
Rv0056rplI0.992
Rv0667rpoB0.992
Rv3457crpoA0.992
Rv0685tuf0.991
Rv2890crpsB0.991
Rv0717rpsN10.991
Rv0685tuf0.991
Rv0685tuf0.991
Rv0732secY0.991
Rv0682rpsL0.99
Rv0668rpoC0.988
Rv2889ctsf0.988
Rv0668rpoC0.988
Rv0668rpoC0.988
Rv0668rpoC0.988
Rv0668rpoC0.988
Rv2889ctsf0.988
Rv2056crpsN20.984
Rv3461crpmJ0.979
Rv2785crpsO0.978
Rv0734mapA0.977
Rv2057crpmG10.977
Rv1298rpmE0.974
Rv2882cfrr0.971
Rv0639nusG0.969
Rv0639nusG0.969
Rv2861cmapB0.968
Rv1015crplY0.964
Rv1015crplY0.964
Rv0053rpsF0.961
Rv2916cffh0.96
Rv2916cffh0.96
Rv2916cffh0.96
Rv0634BrpmG20.959
Rv1641infC0.958
Rv1641infC0.958
Rv2839cinfB0.957
Rv2839cinfB0.957
Rv2839cinfB0.957
Rv2839cinfB0.957
Rv0733adk0.951
Rv2783cgpsI0.95
Rv2783cgpsI0.95
Rv3462cinfA0.95
Rv2783cgpsI0.95
Rv2783cgpsI0.95
Rv2783cgpsI0.95
Rv2462ctig0.949
Rv2462ctig0.949
Rv2462ctig0.949
Rv0120cfusA20.947
Rv0120cfusA20.947
Rv0120cfusA20.947
Rv0120cfusA20.947
Rv2909crpsP0.947
Rv0120cfusA20.947
Rv2906ctrmD0.944
Rv3924crpmH0.935
Rv0055rpsR10.93
Rv3455ctruA0.924
Rv2058crpmB20.909
Rv1297rho0.906
Rv1297rho0.906
Rv1297rho0.906
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
DrugBank IDDrug Name
DB00199DrugBankErythromycin
DB00207DrugBankAzithromycin
DB01321DrugBankJosamycin
DB01361DrugBankTroleandomycin
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.82665.409
magnesiumPubChem0.79724.305
erythromycinPubChem0.734733.927