Rv0714

Tuberculist information
Gene namerplN
Protein function50S ribosomal protein L14 RplN
Functional category(tuberculist)information pathways
Gene location(kb)811.373
Molecular mass(da)13395.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 122
	  		  	1    VIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDAIPGGNVKRGDVVKA   60
			  	61   VVVRTVKERRRPDGSYIKFDENAAVIIKPDNDPRGTRIFGPVGRELREKRFMKIISLAPE  120
			  	121  VL

Known structures in the PDB
No Known structures
1 13 25 37 49 61 73 85 97 109 121 Range: 1 to 122  |  Coverage: 99% Ribosomal_L14 Range: 1 to 122  |  Coverage: 99% 1 Range: 1 to 122  |  Coverage: 99% 1
Number of amino acids : 122
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L14PF002381-122
Mtb Structural Proteome models
Model Number1
Model nameRv0714
Template1WHI    APDBCREDO
Template coverage1_122
Template Identity(%)78.7
Model coverage(%)99.2
Normalized DOPE score-1.368

Structure Models from Chopin
Model Number1
Profileb.39.1.1 - 2.40.150.20
Click for model details
zscore27.87
Residue begin1
Residue end122
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0714Gene nameConfidence Score
Rv0701rplC0.999
Rv0716rplE0.999
Rv0702rplD0.999
Rv0716rplE0.999
Rv0703rplW0.999
Rv0717rpsN10.999
Rv0708rplP0.999
Rv0704rplB0.999
Rv0704rplB0.999
Rv0719rplF0.999
Rv0640rplK0.999
Rv0720rplR0.999
Rv0715rplX0.999
Rv0640rplK0.999
Rv0721rpsE0.998
Rv0641rplA0.998
Rv0707rpsC0.998
Rv0721rpsE0.998
Rv3442crpsI0.998
Rv0707rpsC0.998
Rv3443crplM0.998
Rv0652rplL0.998
Rv0723rplO0.998
Rv3456crplQ0.998
Rv0706rplV0.998
Rv0651rplJ0.997
Rv0722rpmD0.997
Rv0718rpsH0.997
Rv0709rpmC0.997
Rv3459crpsK0.997
Rv0705rpsS0.997
Rv0684fusA10.996
Rv0684fusA10.996
Rv0684fusA10.996
Rv0684fusA10.996
Rv3460crpsM0.996
Rv0700rpsJ0.996
Rv0684fusA10.996
Rv2056crpsN20.994
Rv0710rpsQ0.994
Rv2442crplU0.993
Rv2441crpmA0.992
Rv0682rpsL0.992
Rv3458crpsD0.992
Rv3458crpsD0.992
Rv0668rpoC0.991
Rv3457crpoA0.991
Rv0668rpoC0.991
Rv3457crpoA0.991
Rv0683rpsG0.991
Rv0668rpoC0.991
Rv0668rpoC0.991
Rv0668rpoC0.991
Rv3457crpoA0.991
Rv0667rpoB0.99
Rv1643rplT0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv0732secY0.99
Rv0667rpoB0.99
Rv0667rpoB0.99
Rv2904crplS0.988
Rv0734mapA0.986
Rv2890crpsB0.985
Rv0056rplI0.985
Rv0634BrpmG20.985
Rv0056rplI0.985
Rv0685tuf0.983
Rv0685tuf0.983
Rv0685tuf0.983
Rv0639nusG0.982
Rv0639nusG0.982
Rv2057crpmG10.981
Rv2889ctsf0.98
Rv2889ctsf0.98
Rv2861cmapB0.979
Rv3461crpmJ0.977
Rv3462cinfA0.976
Rv1298rpmE0.971
Rv1015crplY0.968
Rv1015crplY0.968
Rv2882cfrr0.968
Rv0120cfusA20.967
Rv0120cfusA20.967
Rv0120cfusA20.967
Rv0120cfusA20.967
Rv0120cfusA20.967
Rv1023eno0.966
Rv1023eno0.966
Rv1641infC0.959
Rv1641infC0.959
Rv0733adk0.957
Rv2916cffh0.955
Rv2916cffh0.955
Rv2916cffh0.955
Rv3924crpmH0.951
Rv2906ctrmD0.947
Rv0053rpsF0.947
Rv2785crpsO0.942
Rv1699pyrG0.936
Rv1699pyrG0.936
Rv2058crpmB20.917
Rv3455ctruA0.913
Rv2909crpsP0.912
Rv2580chisS0.909
Rv2580chisS0.909
Rv0055rpsR10.903
Rv2839cinfB0.901
Rv2839cinfB0.901
Rv2839cinfB0.901
Rv2839cinfB0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.824.305
d-biotinPubChem0.8244.311
zincPubChem0.79965.409
telithromycinPubChem0.711812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.711812.004
bryamycinPubChem0.7081664.89
nchembio.341-comp1PubChem0.7081664.89