Rv3456c

Tuberculist information
Gene namerplQ
Protein function50S ribosomal protein L17 RplQ
Functional category(tuberculist)information pathways
Gene location(kb)3876.89
Molecular mass(da)19475.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 180
	  		  	1    MPKPTKGPRLGGSSSHQKAILANLATSLFEHGRITTTEPKARALRPYAEKLITHAKKGAL   60
			  	61   HNRREVLKKLRDKDVVHTLFAEIGPFFADRDGGYTRIIKIEARKGDNAPMAVIELVREKT  120
			  	121  VTSEANRARRVAAAQAKAKKAAAMPTEESEAKPAEEGDVVGASEPDAKAPEEPPAEAPEN  180

Known structures in the PDB
No Known structures
1 19 37 55 73 91 109 127 145 163 181 Range: 20 to 116  |  Coverage: 53% Ribosomal_L17 Range: 14 to 117  |  Coverage: 57% 1 Range: 1 to 180  |  Coverage: 99% 1
Number of amino acids : 180
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L17PF0119620-116
Mtb Structural Proteome models
Model Number1
Model nameRv3456c
Template1GD8    APDBCREDO
Template coverage14_118
Template Identity(%)54.8
Model coverage(%)56.9
Normalized DOPE score-1.604

Structure Models from Chopin
Model Number1
Profiled.188.1.1 - 3.90.1030.10
Click for model details
zscore30.91
Residue begin1
Residue end180
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3456cGene nameConfidence Score
Rv0716rplE0.999
Rv0708rplP0.999
Rv0722rpmD0.999
Rv0723rplO0.999
Rv0716rplE0.999
Rv0703rplW0.998
Rv3457crpoA0.998
Rv0704rplB0.998
Rv3457crpoA0.998
Rv0704rplB0.998
Rv3457crpoA0.998
Rv0719rplF0.998
Rv0714rplN0.998
Rv0706rplV0.998
Rv0720rplR0.998
Rv0701rplC0.998
Rv0715rplX0.998
Rv0641rplA0.998
Rv3443crplM0.998
Rv0702rplD0.998
Rv3460crpsM0.997
Rv0652rplL0.997
Rv2904crplS0.997
Rv0640rplK0.997
Rv0640rplK0.997
Rv3459crpsK0.997
Rv0651rplJ0.996
Rv3458crpsD0.996
Rv3458crpsD0.996
Rv0721rpsE0.995
Rv1643rplT0.995
Rv0721rpsE0.995
Rv0710rpsQ0.994
Rv0707rpsC0.993
Rv0683rpsG0.993
Rv0709rpmC0.993
Rv0718rpsH0.993
Rv0056rplI0.993
Rv0707rpsC0.993
Rv0056rplI0.993
Rv0705rpsS0.992
Rv0700rpsJ0.992
Rv3442crpsI0.991
Rv0732secY0.99
Rv2441crpmA0.99
Rv2442crplU0.99
Rv3455ctruA0.989
Rv0682rpsL0.989
Rv0684fusA10.989
Rv0684fusA10.989
Rv0684fusA10.989
Rv0684fusA10.989
Rv0684fusA10.989
Rv0685tuf0.987
Rv0685tuf0.987
Rv2056crpsN20.987
Rv0685tuf0.987
Rv1298rpmE0.985
Rv0734mapA0.984
Rv1015crplY0.983
Rv3461crpmJ0.983
Rv1015crplY0.983
Rv0717rpsN10.981
Rv2861cmapB0.979
Rv2909crpsP0.978
Rv0668rpoC0.978
Rv0668rpoC0.978
Rv0668rpoC0.978
Rv0668rpoC0.978
Rv0668rpoC0.978
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv3462cinfA0.976
Rv2906ctrmD0.974
Rv2890crpsB0.972
Rv2057crpmG10.972
Rv0634BrpmG20.965
Rv0733adk0.965
Rv0053rpsF0.964
Rv1297rho0.961
Rv1297rho0.961
Rv1297rho0.961
Rv2916cffh0.96
Rv2916cffh0.96
Rv2916cffh0.96
Rv2785crpsO0.957
Rv2889ctsf0.952
Rv2889ctsf0.952
Rv2412rpsT0.949
Rv2882cfrr0.948
Rv1308atpA0.946
Rv1308atpA0.946
Rv1308atpA0.946
Rv0055rpsR10.943
Rv1630rpsA0.935
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv2783cgpsI0.933
Rv0639nusG0.929
Rv0639nusG0.929
Rv2907crimM0.926
Rv2907crimM0.926
Rv1641infC0.912
Rv1641infC0.912
Rv1023eno0.91
Rv1023eno0.91
Rv2839cinfB0.901
Rv2839cinfB0.901
Rv2839cinfB0.901
Rv2839cinfB0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.79765.409
magnesiumPubChem0.79724.305