Rv0706

Tuberculist information
Gene namerplV
Protein function50S ribosomal protein L22 RplV
Functional category(tuberculist)information pathways
Gene location(kb)803.689
Molecular mass(da)20380.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 197
	  		  	1    MTAATKATEYPSAVAKARFVRVSPRKARRVIDLVRGRSVSDALDILRWAPQAASGPVAKV   60
			  	61   IASAAANAQNNGGLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVESR  120
			  	121  PAKDQRSAKSSRARRTEASKAASKVGATAPAKKAAAKAPAKKAPASSGVKKTPAKKAPAK  180
			  	181  KAPAKASETSAAKGGSD

Known structures in the PDB
No Known structures
1 20 39 58 77 96 115 134 153 172 191 Range: 15 to 119  |  Coverage: 52% Ribosomal_L22 Range: 15 to 123  |  Coverage: 54% 1 Range: 11 to 123  |  Coverage: 56% 1
Number of amino acids : 197
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L22PF0023715-119
Mtb Structural Proteome models
Model Number1
Model nameRv0706
Template1JZX    LPDBCREDO
Template coverage26_134
Template Identity(%)52.3
Model coverage(%)54.8
Normalized DOPE score0.321

Structure Models from Chopin
Model Number1
Profiled.55.1.1 - 3.90.470.10
Click for model details
zscore28.83
Residue begin11
Residue end123
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0706Gene nameConfidence Score
Rv0707rpsC0.999
Rv0701rplC0.999
Rv0716rplE0.999
Rv0707rpsC0.999
Rv0702rplD0.999
Rv0716rplE0.999
Rv0708rplP0.999
Rv0703rplW0.999
Rv0704rplB0.999
Rv0710rpsQ0.999
Rv0704rplB0.999
Rv0719rplF0.999
Rv0705rpsS0.999
Rv0715rplX0.999
Rv0640rplK0.998
Rv0709rpmC0.998
Rv0723rplO0.998
Rv3456crplQ0.998
Rv0714rplN0.998
Rv0640rplK0.998
Rv0720rplR0.998
Rv0641rplA0.997
Rv0651rplJ0.997
Rv3443crplM0.997
Rv0700rpsJ0.997
Rv0722rpmD0.996
Rv0652rplL0.996
Rv3458crpsD0.995
Rv3458crpsD0.995
Rv2442crplU0.994
Rv3459crpsK0.994
Rv3460crpsM0.994
Rv0721rpsE0.993
Rv2904crplS0.993
Rv0721rpsE0.993
Rv0683rpsG0.993
Rv0718rpsH0.993
Rv0732secY0.993
Rv3442crpsI0.992
Rv2441crpmA0.991
Rv0682rpsL0.991
Rv3457crpoA0.99
Rv3457crpoA0.99
Rv0717rpsN10.99
Rv3457crpoA0.99
Rv2056crpsN20.99
Rv1643rplT0.989
Rv0056rplI0.989
Rv0056rplI0.989
Rv0684fusA10.988
Rv0684fusA10.988
Rv0684fusA10.988
Rv0684fusA10.988
Rv0684fusA10.988
Rv0668rpoC0.984
Rv0668rpoC0.984
Rv0668rpoC0.984
Rv0668rpoC0.984
Rv0668rpoC0.984
Rv2057crpmG10.977
Rv0685tuf0.975
Rv0685tuf0.975
Rv0685tuf0.975
Rv2890crpsB0.974
Rv1298rpmE0.972
Rv0634BrpmG20.97
Rv3461crpmJ0.969
Rv0734mapA0.968
Rv1015crplY0.968
Rv1015crplY0.968
Rv0667rpoB0.967
Rv0667rpoB0.967
Rv0667rpoB0.967
Rv0667rpoB0.967
Rv0667rpoB0.967
Rv0667rpoB0.967
Rv2906ctrmD0.966
Rv2889ctsf0.962
Rv2889ctsf0.962
Rv2861cmapB0.955
Rv1630rpsA0.945
Rv2785crpsO0.941
Rv0053rpsF0.935
Rv3924crpmH0.931
Rv0733adk0.924
Rv2882cfrr0.923
Rv2839cinfB0.921
Rv2839cinfB0.921
Rv2839cinfB0.921
Rv2839cinfB0.921
Rv1641infC0.902
Rv1641infC0.902
Rv1650pheT0.901
Rv1650pheT0.901
Rv1650pheT0.901
Rv1650pheT0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
DrugBank IDDrug Name
DB00199DrugBankErythromycin
DB00207DrugBankAzithromycin
DB01369DrugBankQuinupristin
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.79624.305
zincPubChem0.79665.409
telithromycinPubChem0.779812.004
erythromycinPubChem0.718733.927