Rv2904c

Tuberculist information
Gene namerplS
Protein function50S ribosomal protein L19 RplS
Functional category(tuberculist)information pathways
Gene location(kb)3213.91
Molecular mass(da)13013.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 113
	  		  	1    MNRLDFVDKPSLRDDIPAFNPGDTINVHVKVIEGAKERLQVFKGVVIRRQGGGIRETFTV   60
			  	61   RKESYGVGVERTFPVHSPNIDHIEVVTRGDVRRAKLYYLRELRGKKAKIKEKR

Known structures in the PDB
No Known structures
1 12 23 34 45 56 67 78 89 100 111 Range: 1 to 113  |  Coverage: 99% Ribosomal_L19 Range: 2 to 112  |  Coverage: 97% 1 Range: 1 to 113  |  Coverage: 99% 1
Number of amino acids : 113
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L19PF012451-113
Mtb Structural Proteome models
Model Number1
Model nameRv2904c
Template2AW4    PPDBCREDO
Template coverage2_112
Template Identity(%)53.2
Model coverage(%)97.3
Normalized DOPE score1.45

Structure Models from Chopin
Model Number1
Profileb.34.5.6
Click for model details
zscore30.7
Residue begin1
Residue end113
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2904cGene nameConfidence Score
Rv2906ctrmD0.998
Rv1643rplT0.998
Rv3456crplQ0.997
Rv0641rplA0.997
Rv0640rplK0.996
Rv2441crpmA0.996
Rv0640rplK0.996
Rv2909crpsP0.996
Rv1298rpmE0.995
Rv0708rplP0.995
Rv0720rplR0.995
Rv3443crplM0.994
Rv2442crplU0.994
Rv0056rplI0.994
Rv0056rplI0.994
Rv0702rplD0.994
Rv0719rplF0.993
Rv0706rplV0.993
Rv0701rplC0.993
Rv0652rplL0.993
Rv0716rplE0.992
Rv0716rplE0.992
Rv0723rplO0.989
Rv0704rplB0.988
Rv0704rplB0.988
Rv0714rplN0.988
Rv0703rplW0.987
Rv2916cffh0.986
Rv2916cffh0.986
Rv3459crpsK0.986
Rv0651rplJ0.986
Rv2916cffh0.986
Rv2907crimM0.985
Rv2907crimM0.985
Rv1015crplY0.985
Rv1015crplY0.985
Rv3460crpsM0.983
Rv3442crpsI0.982
Rv0715rplX0.98
Rv0707rpsC0.979
Rv0707rpsC0.979
Rv2882cfrr0.977
Rv3458crpsD0.977
Rv3458crpsD0.977
Rv1641infC0.976
Rv1641infC0.976
Rv2057crpmG10.975
Rv0721rpsE0.975
Rv0721rpsE0.975
Rv2785crpsO0.975
Rv0722rpmD0.974
Rv0705rpsS0.974
Rv0700rpsJ0.969
Rv2889ctsf0.967
Rv2889ctsf0.967
Rv3457crpoA0.967
Rv3457crpoA0.967
Rv3457crpoA0.967
Rv0684fusA10.965
Rv0685tuf0.965
Rv0685tuf0.965
Rv0684fusA10.965
Rv0685tuf0.965
Rv0684fusA10.965
Rv0684fusA10.965
Rv0684fusA10.965
Rv2412rpsT0.963
Rv0053rpsF0.963
Rv0710rpsQ0.957
Rv2890crpsB0.957
Rv3461crpmJ0.955
Rv0634BrpmG20.955
Rv0639nusG0.954
Rv0639nusG0.954
Rv2902crnhB0.954
Rv3100csmpB0.954
Rv0682rpsL0.953
Rv1699pyrG0.946
Rv1699pyrG0.946
Rv0718rpsH0.94
Rv0683rpsG0.937
Rv1630rpsA0.936
Rv0667rpoB0.928
Rv0667rpoB0.928
Rv0667rpoB0.928
Rv0667rpoB0.928
Rv0667rpoB0.928
Rv0667rpoB0.928
Rv1649pheS0.927
Rv1649pheS0.927
Rv2903clepB0.923
Rv2903clepB0.923
Rv1689tyrS0.919
Rv1689tyrS0.919
Rv1406fmt0.918
Rv1406fmt0.918
Rv2908cRv2908c0.918
Rv0709rpmC0.915
Rv0055rpsR10.913
Rv2783cgpsI0.91
Rv2783cgpsI0.91
Rv2921cftsY0.91
Rv2783cgpsI0.91
Rv2921cftsY0.91
Rv2783cgpsI0.91
Rv2783cgpsI0.91
Rv2534cefp0.908
Rv2534cefp0.908
Rv2534cefp0.908
Rv0957purH0.905
Rv0957purH0.905
Rv2992cgltS0.904
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.79824.305
zincPubChem0.79865.409
telithromycinPubChem0.7812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.7812.004