Rv0703

Tuberculist information
Gene namerplW
Protein function50S ribosomal protein L23 RplW
Functional category(tuberculist)information pathways
Gene location(kb)802.133
Molecular mass(da)10957.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 100
	  		  	1    MATLADPRDIILAPVISEKSYGLLDDNVYTFLVRPDSNKTQIKIAVEKIFAVKVASVNTA   60
			  	61   NRQGKRKRTRTGYGKRKSTKRAIVTLAPGSRPIDLFGAPA

Known structures in the PDB
No Known structures
1 11 21 31 41 51 61 71 81 91 101 Range: 8 to 98  |  Coverage: 90% Ribosomal_L23 Range: 4 to 91  |  Coverage: 87% 1 Range: 1 to 100  |  Coverage: 99% 1
Number of amino acids : 100
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ribosomal_L23PF002768-98
Mtb Structural Proteome models
Model Number1
Model nameRv0703
Template1N88    APDBCREDO
Template coverage1_88
Template Identity(%)48.9
Model coverage(%)87.0
Normalized DOPE score-0.537

Structure Models from Chopin
Model Number1
Profiled.12.1.1 - 3.30.70.330
Click for model details
zscore20.09
Residue begin1
Residue end100
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0703Gene nameConfidence Score
Rv2916cffh0.999
Rv0707rpsC0.999
Rv0701rplC0.999
Rv0707rpsC0.999
Rv0702rplD0.999
Rv0708rplP0.999
Rv0704rplB0.999
Rv0704rplB0.999
Rv2916cffh0.999
Rv0705rpsS0.999
Rv0714rplN0.999
Rv2916cffh0.999
Rv0706rplV0.999
Rv0720rplR0.998
Rv0700rpsJ0.998
Rv0715rplX0.998
Rv0640rplK0.998
Rv0716rplE0.998
Rv0641rplA0.998
Rv0716rplE0.998
Rv0723rplO0.998
Rv3456crplQ0.998
Rv0719rplF0.998
Rv0640rplK0.998
Rv3443crplM0.997
Rv0652rplL0.997
Rv0709rpmC0.997
Rv0710rpsQ0.997
Rv0651rplJ0.996
Rv0718rpsH0.996
Rv0722rpmD0.995
Rv3457crpoA0.994
Rv3457crpoA0.994
Rv3458crpsD0.994
Rv3458crpsD0.994
Rv3457crpoA0.994
Rv0721rpsE0.993
Rv0721rpsE0.993
Rv0684fusA10.992
Rv0684fusA10.992
Rv0684fusA10.992
Rv0717rpsN10.992
Rv3459crpsK0.992
Rv0684fusA10.992
Rv0684fusA10.992
Rv0732secY0.991
Rv3460crpsM0.991
Rv0056rplI0.99
Rv0056rplI0.99
Rv0683rpsG0.99
Rv2442crplU0.989
Rv0682rpsL0.989
Rv2056crpsN20.989
Rv3442crpsI0.987
Rv2904crplS0.987
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv0668rpoC0.985
Rv2057crpmG10.984
Rv0634BrpmG20.983
Rv2441crpmA0.981
Rv1643rplT0.979
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0667rpoB0.977
Rv0734mapA0.976
Rv1298rpmE0.974
Rv2889ctsf0.972
Rv2889ctsf0.972
Rv0685tuf0.971
Rv0685tuf0.971
Rv0685tuf0.971
Rv2890crpsB0.97
Rv0639nusG0.969
Rv0639nusG0.969
Rv2861cmapB0.966
Rv3461crpmJ0.963
Rv3462cinfA0.959
Rv2906ctrmD0.955
Rv1015crplY0.953
Rv1015crplY0.953
Rv0733adk0.953
Rv3924crpmH0.95
Rv2462ctig0.949
Rv2462ctig0.949
Rv2462ctig0.949
Rv2839cinfB0.938
Rv2839cinfB0.938
Rv2839cinfB0.938
Rv2839cinfB0.938
Rv2785crpsO0.937
Rv1630rpsA0.934
Rv2882cfrr0.934
Rv0053rpsF0.931
Rv2058crpmB20.93
Rv1297rho0.912
Rv1297rho0.912
Rv1297rho0.912
Rv0120cfusA20.909
Rv0120cfusA20.909
Rv0120cfusA20.909
Rv3455ctruA0.909
Rv0120cfusA20.909
Rv0120cfusA20.909
Rv2909crpsP0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.79765.409
magnesiumPubChem0.79724.305
telithromycinPubChem0.702812.004
(1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-1PubChem0.702812.004