Tuberculist information
Gene namerho
Protein functionProbable transcription termination factor Rho homolog
Functional category(tuberculist)information pathways
Gene location(kb)1453.2
Molecular mass(da)65101.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 602
	  		  	1    VTDTDLITAGESTDGKPSDAAATDPPDLNADEPAGSLATMVLPELRALANRAGVKGTSGM   60
			  	61   RKNELIAAIEEIRRQANGAPAVDRSAQEHDKGDRPPSSEAPATQGEQTPTEQIDSQSQQV  120
			  	121  RPERRSATREAGPSGSGERAGTAADDTDNRQGGQQDAKTEERGTDAGGDQGGDQQASGGQ  180
			  	181  QARGDEDGEARQGRRGRRFRDRRRRGERSGDGAEAELREDDVVQPVAGILDVLDNYAFVR  240
			  	241  TSGYLPGPHDVYVSMNMVRKNGMRRGDAVTGAVRVPKEGEQPNQRQKFNPLVRLDSINGG  300
			  	301  SVEDAKKRPEFGKLTPLYPNQRLRLETSTERLTTRVIDLIMPIGKGQRALIVSPPKAGKT  360
			  	361  TILQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAEL  420
			  	421  AIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAAR  480
			  	481  NIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGT  540
			  	541  RKDELLLSPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKTTPGSMD  600
			  	601  SD
			  			

Known structures in the PDB
No Known structures
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Rho_NPF0749836-78
Rho_RNA_bindPF07497225-304
ATP-synt_abPF00006332-540
Mtb Structural Proteome models
Model Number1
Model nameRv1297
Template1PV4    APDBCREDO
Template coverage18_412
Template Identity(%)54.7
Model coverage(%)63.3
Normalized DOPE score-0.766

Structure Models from Chopin
Model Number1
Profileb.40.4.5, c.37.1.11 - 2.40.50.140, 3.40.50.300
Click for model details
zscore84.23
Residue begin226
Residue end592
Model Number2
Profilea.140.3.1, b.40.4.5, c.37.1.11 - 2.40.50.140, 3.40.50.300
Click for model details
zscore82.26
Residue begin32
Residue end592
Model Number3
Profilec.46.1.4
Click for model details
zscore9.35
Residue begin358
Residue end478
Model Number4
Profilec.65.1.1 - 3.40.50.170
Click for model details
zscore8.69
Residue begin346
Residue end566
Model Number5
Profilea.140.2.1
Click for model details
zscore4.78
Residue begin36
Residue end77
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1297Gene nameConfidence Score
Rv0639nusG0.992
Rv0639nusG0.992
Rv1298rpmE0.976
Rv3457crpoA0.974
Rv3457crpoA0.974
Rv3457crpoA0.974
Rv3458crpsD0.967
Rv3458crpsD0.967
Rv3459crpsK0.963
Rv3456crplQ0.961
Rv0667rpoB0.95
Rv0667rpoB0.95
Rv0667rpoB0.95
Rv0667rpoB0.95
Rv0667rpoB0.95
Rv0667rpoB0.95
Rv1630rpsA0.947
Rv3460crpsM0.941
Rv0701rplC0.935
Rv0721rpsE0.93
Rv0721rpsE0.93
Rv3248csahH0.929
Rv3248csahH0.929
Rv1292argS0.92
Rv1292argS0.92
Rv1292argS0.92
Rv1299prfA0.919
Rv1299prfA0.919
Rv0707rpsC0.912
Rv0703rplW0.912
Rv0707rpsC0.912
Rv0641rplA0.908
Rv2412rpsT0.907
Rv0702rplD0.906
Rv0700rpsJ0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
bicyclomycinPubChem0.958302.281
sulfatePubChem0.78496.0626
hydron sulfatePubChem0.784196.157