Rv3153

Tuberculist information
Gene namenuoI
Protein functionProbable NADH dehydrogenase I (chain I) NuoI (NADH-ubiquinone oxidoreductase chain I)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3520.51
Molecular mass(da)23434.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 211
	  		  	1    VANTDRPALPHKRAVPPSRADSGPRRRRTKLLDAVAGFGVTLGSMFKKTVTEEYPERPGP   60
			  	61   VAARYHGRHQLNRYPDGLEKCIGCELCAWACPADAIYVEGADNTEEERFSPGERYGRVYQ  120
			  	121  INYLRCIGCGLCIEACPTRALTMTYDYELADDNRADLIYEKDRLLAPLLPEMAAPPHPRT  180
			  	181  PGATDKDYYLGNVTAEGLRGVRESQTTGDSR

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 80 to 140  |  Coverage: 28% Fer4_7 Range: 54 to 211  |  Coverage: 74% 1 Range: 5 to 210  |  Coverage: 97% 1
Number of amino acids : 211
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Fer4_7PF1283880-140
Mtb Structural Proteome models
Model Number1
Model nameRv3153
Template2FUG    9PDBCREDO
Template coverage26_178
Template Identity(%)47.7
Model coverage(%)74.4
Normalized DOPE score0.021

Structure Models from Chopin
Model Number1
Profiled.58.1.5
Click for model details
zscore15.38
Residue begin5
Residue end210
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3153Gene nameConfidence Score
Rv3156nuoL0.999
Rv3151nuoG0.999
Rv3149nuoE0.999
Rv3157nuoM0.999
Rv3151nuoG0.999
Rv3150nuoF0.999
Rv3158nuoN0.999
Rv3152nuoH0.999
Rv3150nuoF0.999
Rv3145nuoA0.999
Rv3154nuoJ0.999
Rv3150nuoF0.999
Rv3146nuoB0.999
Rv3155nuoK0.999
Rv3151nuoG0.999
Rv3147nuoC0.999
Rv3156nuoL0.999
Rv3151nuoG0.999
Rv3148nuoD0.999
Rv0082Rv00820.954
Rv1310atpD0.937
Rv1310atpD0.937
Rv1310atpD0.937
Rv1308atpA0.921
Rv1308atpA0.921
Rv1308atpA0.921
Rv0086hycQ0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
reduced nicotinamide adenine dinucleotidePubChem0.976665.441
ubiquinonesPubChem0.934250.29
NAD+PubChem0.923663.425
CoQPubChem0.915318.407
ubiquinol-1PubChem0.9252.306
ubiquinolPubChem0.9320.423
dihydronicotinamide formycin dinucleotidePubChem0.9665.441
flavin mononucleotidePubChem0.892456.344
4Fe-4SPubChem0.81288.9179
rotenonePubChem0.722394.417
calciumPubChem0.70340.078