Rv2154c

Tuberculist information
Gene nameftsW
Protein functionFtsW-like protein FtsW
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2413.35
Molecular mass(da)56304.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 524
	  		  	1    VLTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLI   60
			  	61   IAVAALLTTLGLIMVLSASAVRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMR  120
			  	121  RIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVAGFSMQPSELAKMAFAIWGAHLLAA  180
			  	181  RRMERASLREMLIPLVPAAVVALALIVAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSL  240
			  	241  AAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVA  300
			  	301  KWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLTATTT  360
			  	361  LWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLSLIGIIANAARHEPEAVAALR  420
			  	421  AGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGL  480
			  	481  PPRPGSPRTADPPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG

Known structures in the PDB
No Known structures
1 53 105 157 209 261 313 365 417 469 521 Range: 57 to 414  |  Coverage: 68% FTSW_RODA_SPOVE
Number of amino acids : 524
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
FTSW_RODA_SPOVEPF0109857-414
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2154cGene nameConfidence Score
Rv2150cftsZ0.999
Rv2153cmurG0.999
Rv2155cmurD0.999
Rv2158cmurE0.999
Rv2155cmurD0.999
Rv2158cmurE0.999
Rv2158cmurE0.999
Rv2150cftsZ0.999
Rv2153cmurG0.999
Rv2157cmurF0.997
Rv2157cmurF0.997
Rv2157cmurF0.997
Rv2152cmurC0.995
Rv2156cmurX0.995
Rv2152cmurC0.995
Rv2156cmurX0.995
Rv2152cmurC0.995
Rv2163cpbpB0.993
Rv2163cpbpB0.993
Rv2151cftsQ0.985
Rv2151cftsQ0.985
Rv2981cddlA0.982
Rv2981cddlA0.982
Rv2165cRv2165c0.98
Rv2166cRv2166c0.968
Rv1315murA0.966
Rv2748cftsK0.965
Rv2748cftsK0.965
Rv2748cftsK0.965
Rv0482murB0.962
Rv0482murB0.962
Rv0016cpbpA0.959
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions