Rv2166c

Tuberculist information
Gene nameRv2166c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2429.43
Molecular mass(da)15911.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 143
	  		  	1    MFLGTYTPKLDDKGRLTLPAKFRDALAGGLMVTKSQDHSLAVYPRAAFEQLARRASKAPR   60
			  	61   SNPEARAFLRNLAAGTDEQHPDSQGRITLSADHRRYASLSKDCVVIGAVDYLEIWDAQAW  120
			  	121  QNYQQIHEENFSAASDEALGDIF

Known structures in the PDB
No Known structures
1 15 29 43 57 71 85 99 113 127 141 Range: 1 to 71  |  Coverage: 48% MraZ Range: 72 to 142  |  Coverage: 48% MraZ Range: 1 to 138  |  Coverage: 95% 1 Range: 1 to 137  |  Coverage: 95% 1
Number of amino acids : 143
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MraZPF023811-71
MraZPF0238172-142
Mtb Structural Proteome models
Model Number1
Model nameRv2166c
Template1N0E    APDBCREDO
Template coverage26_162
Template Identity(%)27.7
Model coverage(%)95.8
Normalized DOPE score-0.902

Structure Models from Chopin
Model Number1
Profileb.129.1.2
Click for model details
zscore31.81
Residue begin1
Residue end137
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2166cGene nameConfidence Score
Rv2165cRv2165c0.999
Rv2158cmurE0.98
Rv2158cmurE0.98
Rv2158cmurE0.98
Rv2163cpbpB0.974
Rv2163cpbpB0.974
Rv2150cftsZ0.973
Rv2150cftsZ0.973
Rv2154cftsW0.968
Rv2155cmurD0.964
Rv2155cmurD0.964
Rv0017crodA0.955
Rv0482murB0.949
Rv0482murB0.949
Rv2981cddlA0.944
Rv2981cddlA0.944
Rv2404clepA0.937
Rv2404clepA0.937
Rv2404clepA0.937
Rv2404clepA0.937
Rv2156cmurX0.925
Rv2156cmurX0.925
Rv2153cmurG0.911
Rv2153cmurG0.911
Rv2157cmurF0.91
Rv2157cmurF0.91
Rv2157cmurF0.91
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions