Rv3324c

Tuberculist information
Gene namemoaC3
Protein functionProbable molybdenum cofactor biosynthesis protein C 3 MoaC3
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3709.72
Molecular mass(da)18523.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 177
	  		  	1    VNDHDGVLTHLDEQGAARMVDVSAKAVTLRRARASGAVLMKPSTLDMICHGTAAKGDVIA   60
			  	61   TARIAGIMAAKRTGELIPLCHPLGIEAVTVTLEPQGADRLSIAATVTTVARTGVEMEALT  120
			  	121  AVTVTALTVYDMCKAVDRAMTITDIRLDEKSGGRSGHYRRHDADVKPSDGGSTEDGC

Known structures in the PDB
No Known structures
1 18 35 52 69 86 103 120 137 154 171 Range: 19 to 153  |  Coverage: 75% MoaC Range: 15 to 159  |  Coverage: 81% 1 Range: 15 to 156  |  Coverage: 79% 1
Number of amino acids : 177
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MoaCPF0196719-153
Mtb Structural Proteome models
Model Number1
Model nameRv3324c
Template1EKR    APDBCREDO
Template coverage11_156
Template Identity(%)55.9
Model coverage(%)81.4
Normalized DOPE score-0.361

Structure Models from Chopin
Model Number1
Profiled.58.21.1 - 3.30.70.640
Click for model details
zscore28.77
Residue begin15
Residue end156
Binding pockets
STRING
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Protein interacting with Rv3324cGene nameConfidence Score
Rv3323cmoaX0.997
Rv3323cmoaX0.997
Rv0869cmoaA20.993
Rv0869cmoaA20.993
Rv0869cmoaA20.993
Rv3109moaA10.982
Rv3109moaA10.982
Rv3109moaA10.982
Rv3119moaE10.98
Rv0866moaE20.977
Rv0865mog0.959
Rv3112moaD10.958
Rv0984moaB20.941
Rv3116moeB20.929
Rv3116moeB20.929
Rv3116moeB20.929
Rv0438cmoeA20.917
Rv0438cmoeA20.917
Rv0438cmoeA20.917
Rv0994moeA10.915
Rv3609cfolE0.915
Rv0994moeA10.915
Rv0994moeA10.915
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions