Tuberculist information
Gene namemoaC2
Protein functionProbable molybdenum cofactor biosynthesis protein C 2 MoaC2
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)962.89
Molecular mass(da)17598.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 167
	  		  	1    MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGL   60
			  	61   PKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGV  120
			  	121  EMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
			  			

Known structures in the PDB
PDB ID4FDF
Total residue count350
Number of chains2
MethodX-RAY
Resolution2.2
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MoaCPF0196726-159
Mtb Structural Proteome models
Model Number1
Model nameRv0864
Template1EKR    APDBCREDO
Template coverage11_153
Template Identity(%)51.4
Model coverage(%)82.0
Normalized DOPE score-0.416

Structure Models from Chopin
Model Number1
Profiled.58.21.1 - 3.30.70.640
Click for model details
zscore31.32
Residue begin22
Residue end162
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0864Gene nameConfidence Score
Rv0866moaE20.997
Rv0865mog0.995
Rv0869cmoaA20.994
Rv0869cmoaA20.994
Rv0869cmoaA20.994
Rv3119moaE10.984
Rv3323cmoaX0.971
Rv3323cmoaX0.971
Rv3109moaA10.966
Rv3109moaA10.966
Rv3109moaA10.966
Rv0984moaB20.95
Rv0438cmoeA20.93
Rv0438cmoeA20.93
Rv0438cmoeA20.93
Rv3112moaD10.92
Rv0994moeA10.92
Rv0994moeA10.92
Rv0994moeA10.92
Rv3609cfolE0.916
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions