Gene name | serB2 |
Protein function | Probable phosphoserine phosphatase SerB2 (PSP) (O-phosphoserine phosphohydrolase) (pspase) |
Functional category(tuberculist) | intermediary metabolism and respiration |
Gene location(kb) | 3401.93 |
Molecular mass(da) | 43058.7 |
External sites | TB Database TubercuList WebTB |
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1 MPAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVAD 60 61 GTALRDDVAAAIHGVGLDVAIERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAAL 120 121 GVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKR 180 181 LIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPAT 240 241 VIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIV 300 301 DGILTGRVVGPIVDRPGKAKALRDFASQYGVPMEQTVAVGDGANDIDMLGAAGLGIAFNA 360 361 KPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAGDCGVRRVEIPAD
Structural/Functional domain family | Pfam acc.no./SCOP ID | Domain Region | |
---|---|---|---|
ACT_6 | PF13740 | 6-82 | |
HAD | PF12710 | 182-350 |
Model Number | 1 |
Profile | c.108.1.4 Click for model details |
---|---|
zscore | 41.27 |
Residue begin | 170 |
Residue end | 385 |
Model Number | 2 |
Profile | d.58.18.7 - 3.30.70.260 Click for model details |
---|---|
zscore | 18.34 |
Residue begin | 6 |
Residue end | 82 |
Model Number | 3 |
Profile | d.58.18.3 Click for model details |
---|---|
zscore | 6.48 |
Residue begin | 96 |
Residue end | 164 |
Protein interacting with Rv3042c | Gene name | Confidence Score |
---|---|---|
Rv0884c | serC | 0.994 |
Rv1093 | glyA1 | 0.993 |
Rv0070c | glyA2 | 0.993 |
Rv2996c | serA1 | 0.988 |
Rv2996c | serA1 | 0.988 |
Rv2996c | serA1 | 0.988 |
Rv0069c | sdaA | 0.984 |
Rv0069c | sdaA | 0.984 |
Rv1612 | trpB | 0.964 |
Rv1613 | trpA | 0.956 |
Rv1559 | ilvA | 0.943 |
Rv1559 | ilvA | 0.943 |
Rv2335 | cysE | 0.927 |
Rv2335 | cysE | 0.927 |
Rv1077 | cbs | 0.921 |
Rv1077 | cbs | 0.921 |
Rv0436c | pssA | 0.92 |
Rv1601 | hisB | 0.914 |
Protein Model | Pocket Number | Drug Binding Site | PMIN Score | Pvalue PMIN | PMAX Score | Pvalue PMAX |
---|---|---|---|---|---|---|
Rv3042c.1 | 6 | 2y6o_1N1_A_1892PDBCREDO | 0.650 | 0.124 | 0.609 | 0.002 |
Rv3042c.1 | 4 | 3ndt_ROC_A_101PDBCREDO | 0.600 | 0.179 | 0.587 | 0.003 |
Rv3042c.1 | 6 | 3spk_TPV_A_100PDBCREDO | 0.601 | 0.178 | 0.581 | 0.003 |
Rv3042c.1 | 6 | 2fum_MIX_D_3539PDBCREDO | 0.617 | 0.159 | 0.577 | 0.003 |
Rv3042c.1 | 4 | 3k4v_ROC_B_201PDBCREDO | 0.600 | 0.179 | 0.575 | 0.003 |
Rv3042c.1 | 6 | 3oht_1N1_B_1000PDBCREDO | 0.658 | 0.117 | 0.574 | 0.003 |
Rv3042c.1 | 6 | 3oez_STI_B_601PDBCREDO | 0.632 | 0.143 | 0.573 | 0.003 |
Rv3042c.1 | 4 | 3tkg_ROC_B_801PDBCREDO | 0.608 | 0.170 | 0.571 | 0.004 |
Rv3042c.1 | 4 | 3oxc_ROC_A_401PDBCREDO | 0.630 | 0.145 | 0.567 | 0.004 |
Rv3042c.1 | 6 | 3hec_STI_A_1PDBCREDO | 0.621 | 0.154 | 0.564 | 0.004 |
Rv3042c.1 | 4 | 3ndu_ROC_A_101PDBCREDO | 0.599 | 0.180 | 0.564 | 0.004 |
Rv3042c.1 | 6 | 4asd_BAX_A_1500PDBCREDO | 0.702 | 0.080 | 0.564 | 0.004 |
Rv3042c.1 | 6 | 2jfa_RAL_A_600PDBCREDO | 0.620 | 0.156 | 0.562 | 0.004 |
Rv3042c.1 | 6 | 2xkw_P1B_B_1475PDBCREDO | 0.664 | 0.111 | 0.558 | 0.004 |
Rv3042c.1 | 6 | 3bbt_FMM_D_91PDBCREDO | 0.594 | 0.186 | 0.555 | 0.005 |
Rv3042c.1 | 6 | 1qkn_RAL_A_600PDBCREDO | 0.571 | 0.215 | 0.553 | 0.005 |
Rv3042c.1 | 6 | 3v5w_8PR_A_701PDBCREDO | 0.571 | 0.215 | 0.553 | 0.005 |
Rv3042c.1 | 6 | 1s9p_DES_A_459PDBCREDO | 0.632 | 0.143 | 0.551 | 0.005 |
Rv3042c.1 | 6 | 1err_RAL_B_600PDBCREDO | 0.624 | 0.151 | 0.549 | 0.005 |
Rv3042c.1 | 6 | 2jfa_RAL_B_600PDBCREDO | 0.624 | 0.151 | 0.549 | 0.005 |
Rv3042c.1 | 6 | 3oct_1N1_A_663PDBCREDO | 0.607 | 0.170 | 0.549 | 0.005 |
Rv3042c.1 | 6 | 1err_RAL_A_600PDBCREDO | 0.621 | 0.154 | 0.547 | 0.005 |
Rv3042c.1 | 6 | 3oht_1N1_A_1000PDBCREDO | 0.699 | 0.082 | 0.546 | 0.005 |
Rv3042c.1 | 4 | 1ya4_CTX_A_1PDBCREDO | 0.762 | 0.042 | 0.545 | 0.005 |
Rv3042c.1 | 6 | 1zgy_BRL_A_503PDBCREDO | 0.562 | 0.228 | 0.543 | 0.006 |
Rv3042c.1 | 6 | 1uwh_BAX_B_1723PDBCREDO | 0.637 | 0.138 | 0.543 | 0.006 |
Rv3042c.1 | 6 | 3tne_RIT_A_401PDBCREDO | 0.598 | 0.182 | 0.543 | 0.006 |
Rv3042c.1 | 6 | 1uwh_BAX_A_1723PDBCREDO | 0.636 | 0.139 | 0.543 | 0.006 |
Rv3042c.1 | 6 | 2hyy_STI_B_600PDBCREDO | 0.655 | 0.119 | 0.542 | 0.006 |
Rv3042c.1 | 4 | 3tl9_ROC_A_401PDBCREDO | 0.629 | 0.146 | 0.542 | 0.006 |
Rv3042c.1 | 6 | 1bsx_T3_A_1PDBCREDO | 0.559 | 0.232 | 0.541 | 0.006 |
Rv3042c.1 | 6 | 1bsx_T3_B_2PDBCREDO | 0.559 | 0.232 | 0.541 | 0.006 |
Rv3042c.1 | 6 | 1jg2_ADN_A_500PDBCREDO | 0.599 | 0.180 | 0.541 | 0.006 |
Rv3042c.1 | 6 | 3gws_T3_X_500PDBCREDO | 0.557 | 0.234 | 0.539 | 0.006 |
Rv3042c.1 | 6 | 1s9p_DES_D_600PDBCREDO | 0.612 | 0.165 | 0.534 | 0.006 |
Rv3042c.1 | 4 | 3bvb_017_B_401PDBCREDO | 0.745 | 0.051 | 0.534 | 0.007 |
Rv3042c.1 | 6 | 3k54_1N1_A_1PDBCREDO | 0.656 | 0.119 | 0.532 | 0.007 |
Rv3042c.1 | 6 | 3heg_BAX_A_1PDBCREDO | 0.640 | 0.135 | 0.530 | 0.007 |
Rv3042c.1 | 6 | 1xzx_T3_X_500PDBCREDO | 0.565 | 0.223 | 0.529 | 0.007 |
Rv3042c.1 | 6 | 3uvv_T3_A_501PDBCREDO | 0.565 | 0.223 | 0.529 | 0.007 |
Rv3042c.1 | 6 | 2h79_T3_A_1PDBCREDO | 0.529 | 0.274 | 0.529 | 0.007 |
Rv3042c.1 | 6 | 3jwq_VIA_D_901PDBCREDO | 0.565 | 0.224 | 0.528 | 0.007 |
Rv3042c.1 | 6 | 2fum_MIX_A_539PDBCREDO | 0.627 | 0.149 | 0.527 | 0.007 |
Rv3042c.1 | 4 | 3mws_017_B_201PDBCREDO | 0.561 | 0.228 | 0.527 | 0.007 |
Rv3042c.1 | 4 | 2f80_017_B_301PDBCREDO | 0.770 | 0.037 | 0.525 | 0.007 |
Rv3042c.1 | 6 | 2h77_T3_A_1PDBCREDO | 0.542 | 0.255 | 0.525 | 0.007 |
Rv3042c.1 | 6 | 2oiq_STI_A_1001PDBCREDO | 0.633 | 0.142 | 0.524 | 0.008 |
Rv3042c.1 | 4 | 3d1x_ROC_A_201PDBCREDO | 0.581 | 0.203 | 0.523 | 0.008 |
Rv3042c.1 | 6 | 1uwj_BAX_B_1723PDBCREDO | 0.650 | 0.124 | 0.522 | 0.008 |
Rv3042c.1 | 6 | 3gcs_BAX_A_401PDBCREDO | 0.650 | 0.124 | 0.522 | 0.008 |
Rv3042c.1 | 6 | 2hw2_RFP_A_1200PDBCREDO | 0.575 | 0.210 | 0.522 | 0.008 |
Rv3042c.1 | 4 | 2nmy_ROC_A_401PDBCREDO | 0.632 | 0.143 | 0.521 | 0.008 |
Rv3042c.1 | 6 | 3tne_RIT_B_401PDBCREDO | 0.573 | 0.213 | 0.520 | 0.008 |
Rv3042c.1 | 6 | 1kij_NOV_A_400PDBCREDO | 0.555 | 0.237 | 0.519 | 0.008 |
Rv3042c.1 | 6 | 2pl0_STI_A_200PDBCREDO | 0.626 | 0.149 | 0.518 | 0.008 |
Rv3042c.1 | 6 | 2gqg_1N1_A_501PDBCREDO | 0.614 | 0.163 | 0.516 | 0.009 |
Rv3042c.1 | 6 | 3erd_DES_A_600PDBCREDO | 0.614 | 0.163 | 0.516 | 0.009 |
Rv3042c.1 | 6 | 1fm6_BRL_X_504PDBCREDO | 0.551 | 0.243 | 0.516 | 0.009 |
Rv3042c.1 | 6 | 3erd_DES_B_800PDBCREDO | 0.612 | 0.165 | 0.515 | 0.009 |
Rv3042c.1 | 6 | 1jg3_ADN_A_500PDBCREDO | 0.634 | 0.141 | 0.514 | 0.009 |
Rv3042c.1 | 6 | 3qlg_1N1_A_601PDBCREDO | 0.707 | 0.075 | 0.513 | 0.009 |
Rv3042c.1 | 6 | 4eyb_0WO_A_303PDBCREDO | 0.588 | 0.194 | 0.513 | 0.009 |
Rv3042c.1 | 4 | 3cyx_ROC_A_201PDBCREDO | 0.634 | 0.140 | 0.511 | 0.009 |
Rv3042c.1 | 4 | 3ndu_ROC_D_100PDBCREDO | 0.634 | 0.141 | 0.511 | 0.009 |
Rv3042c.1 | 4 | 3tkw_017_B_401PDBCREDO | 0.580 | 0.204 | 0.511 | 0.009 |
Rv3042c.1 | 6 | 2gqg_1N1_B_502PDBCREDO | 0.510 | 0.302 | 0.510 | 0.009 |
Rv3042c.1 | 6 | 3qlg_1N1_B_601PDBCREDO | 0.704 | 0.077 | 0.510 | 0.009 |
Rv3042c.1 | 4 | 2f8g_017_B_401PDBCREDO | 0.555 | 0.237 | 0.510 | 0.009 |
Rv3042c.1 | 4 | 3s54_017_B_201PDBCREDO | 0.554 | 0.238 | 0.510 | 0.009 |
Rv3042c.1 | 6 | 1fm6_BRL_D_503PDBCREDO | 0.583 | 0.200 | 0.509 | 0.010 |
Rv3042c.1 | 6 | 2zva_1N1_A_513PDBCREDO | 0.730 | 0.060 | 0.509 | 0.010 |
Rv3042c.1 | 6 | 1lhv_NOG_A_301PDBCREDO | 0.542 | 0.255 | 0.508 | 0.010 |
Rv3042c.1 | 4 | 3sm2_478_A_126PDBCREDO | 0.763 | 0.041 | 0.507 | 0.010 |
Rv3042c.1 | 6 | 1t7j_478_A_200PDBCREDO | 0.594 | 0.186 | 0.507 | 0.010 |
Rv3042c.1 | 6 | 2cbr_A80_A_201PDBCREDO | 0.648 | 0.127 | 0.507 | 0.010 |
Rv3042c.1 | 6 | 3g5d_1N1_A_1PDBCREDO | 0.699 | 0.081 | 0.507 | 0.010 |
Rv3042c.1 | 6 | 2prg_BRL_A_1PDBCREDO | 0.580 | 0.204 | 0.505 | 0.010 |
Rv3042c.1 | 6 | 3bbt_FMM_B_91PDBCREDO | 0.671 | 0.105 | 0.505 | 0.010 |
Rv3042c.1 | 6 | 3h0a_9RA_A_500PDBCREDO | 0.540 | 0.258 | 0.505 | 0.010 |
Rv3042c.1 | 6 | 3pyy_STI_B_4PDBCREDO | 0.666 | 0.109 | 0.505 | 0.010 |
Rv3042c.1 | 6 | 1uwj_BAX_A_1723PDBCREDO | 0.685 | 0.092 | 0.505 | 0.010 |
Rv3042c.1 | 4 | 2aof_FRD_C_305PDBCREDO | 0.656 | 0.119 | 0.505 | 0.010 |
Rv3042c.1 | 4 | 3tkg_ROC_C_901PDBCREDO | 0.641 | 0.133 | 0.505 | 0.010 |
Rv3042c.1 | 6 | 3k5v_STI_B_2PDBCREDO | 0.665 | 0.110 | 0.504 | 0.010 |
Rv3042c.1 | 6 | 3g5d_1N1_B_1PDBCREDO | 0.695 | 0.084 | 0.504 | 0.010 |
Rv3042c.1 | 4 | 2q64_1UN_B_1001PDBCREDO | 0.739 | 0.054 | 0.503 | 0.010 |
Rv3042c.1 | 4 | 3ucb_017_A_201PDBCREDO | 0.686 | 0.092 | 0.503 | 0.010 |
Rv3042c.1 | 4 | 2qak_1UN_A_1001PDBCREDO | 0.738 | 0.055 | 0.503 | 0.010 |
Rv3042c.1 | 6 | 2hyy_STI_A_600PDBCREDO | 0.663 | 0.112 | 0.503 | 0.010 |
Rv3042c.1 | 6 | 3ms9_STI_A_1PDBCREDO | 0.663 | 0.112 | 0.503 | 0.010 |
Rv3042c.1 | 6 | 3ms9_STI_B_1PDBCREDO | 0.663 | 0.112 | 0.503 | 0.010 |
Rv3042c.1 | 4 | 2nmz_ROC_B_401PDBCREDO | 0.657 | 0.118 | 0.502 | 0.011 |
Rv3042c.1 | 4 | 2pyn_1UN_A_1001PDBCREDO | 0.737 | 0.056 | 0.502 | 0.011 |
Rv3042c.1 | 4 | 2pym_1UN_A_1001PDBCREDO | 0.736 | 0.056 | 0.502 | 0.011 |
Rv3042c.1 | 6 | 2hyy_STI_C_600PDBCREDO | 0.662 | 0.113 | 0.501 | 0.011 |
Rv3042c.1 | 6 | 3mss_STI_D_1PDBCREDO | 0.662 | 0.113 | 0.501 | 0.011 |
Rv3042c.1 | 6 | 3mss_STI_A_1PDBCREDO | 0.661 | 0.114 | 0.501 | 0.011 |
Rv3042c.1 | 6 | 3mss_STI_B_1PDBCREDO | 0.661 | 0.114 | 0.501 | 0.011 |
Rv3042c.1 | 4 | 2q63_1UN_A_1001PDBCREDO | 0.735 | 0.057 | 0.501 | 0.011 |
Rv3042c.1 | 6 | 3gvu_STI_A_1001PDBCREDO | 0.661 | 0.114 | 0.501 | 0.011 |
Chemical Name | Confidence score | Molecular Weight |
---|---|---|
phosphatePubChem | 0.968 | 96.9872 |
O-phosphoserinePubChem | 0.967 | 185.072 |
L-serinePubChem | 0.956 | 105.093 |
hydroxyl radicalsPubChem | 0.9 | 17.0073 |
magnesiumPubChem | 0.809 | 24.305 |
chloridePubChem | 0.772 | 35.453 |
sulfatePubChem | 0.768 | 96.0626 |
hydron sulfatePubChem | 0.768 | 196.157 |
selenomethioninePubChem | 0.757 | 196.106 |
SeMetPubChem | 0.757 | 196.106 |