Gene name | frdA |
Protein function | Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) (fumaric hydrogenase) |
Functional category(tuberculist) | intermediary metabolism and respiration |
Gene location(kb) | 1757.68 |
Molecular mass(da) | 63763.1 |
External sites | TB Database TubercuList WebTB |
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1 MTAQHNIVVIGGGGAGLRAAIAIAETNPHLDVAIVSKVYPMRSHTVSAEGGAAAVTGDDD 60 61 SLDEHAHDTVSGGDWLCDQDAVEAFVAEAPKELVQLEHWGCPWSRKPDGRVAVRPFGGMK 120 121 KLRTWFAADKTGFHLLHTLFQRLLTYSDVMRYDEWFATTLLVDDGRVCGLVAIELATGRI 180 181 ETILADAVILCTGGCGRVFPFTTNANIKTGDGMALAFRAGAPLKDMEFVQYHPTGLPFTG 240 241 ILITEAARAEGGWLLNKDGYRYLQDYDLGKPTPEPRLRSMELGPRDRLSQAFVHEHNKGR 300 301 TVDTPYGPVVYLDLRHLGADLIDAKLPFVRELCRDYQHIDPVVELVPVRPVVHYMMGGVH 360 361 TDINGATTLPGLYAAGETACVSINGANRLGSNSLPELLVFGARAGRAAADYAARHQKSDR 420 421 GPSSAVRAQARTEALRLERELSRHGQGGERIADIRADMQATLESAAGIYRDGPTLTKAVE 480 481 EIRVLQERFATAGIDDHSRTFNTELTALLELSGMLDVALAIVESGLRREESRGAHQRTDF 540 541 PNRDDEHFLAHTLVHRESDGTLRVGYLPVTITRWPPGERVYGR
Structural/Functional domain family | Pfam acc.no./SCOP ID | Domain Region | |
---|---|---|---|
FAD_binding_2 | PF00890 | 6-394 | |
Succ_DH_flav_C | PF02910 | 455-581 |
Model Number | 1 |
Profile | 1.20.58.100, 3.50.50.60, 3.90.700.10, 4.10.80.40 Click for model details |
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zscore | 97.58 |
Residue begin | 1 |
Residue end | 581 |
Model Number | 2 |
Profile | a.7.3.1 Click for model details |
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zscore | 27.56 |
Residue begin | 438 |
Residue end | 583 |
Model Number | 3 |
Profile | a.138.1.3, d.168.1.1 - 1.10.1130.10, 3.50.50.60, 3.90.700.10 Click for model details |
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zscore | 26.35 |
Residue begin | 1 |
Residue end | 414 |
Model Number | 4 |
Profile | 3.90.700.10 Click for model details |
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zscore | 20.5 |
Residue begin | 228 |
Residue end | 354 |
Model Number | 5 |
Profile | 1.20.58.100 Click for model details |
---|---|
zscore | 18.35 |
Residue begin | 424 |
Residue end | 545 |
Model Number | 6 |
Profile | 4.10.80.40 Click for model details |
---|---|
zscore | 10.14 |
Residue begin | 542 |
Residue end | 580 |
Model Number | 7 |
Profile | c.5.1.1 Click for model details |
---|---|
zscore | 4.24 |
Residue begin | 1 |
Residue end | 97 |
Protein interacting with Rv1552 | Gene name | Confidence Score |
---|---|---|
Rv1553 | frdB | 0.999 |
Rv1553 | frdB | 0.999 |
Rv1554 | frdC | 0.999 |
Rv1555 | frdD | 0.997 |
Rv0952 | sucD | 0.994 |
Rv0952 | sucD | 0.994 |
Rv0951 | sucC | 0.992 |
Rv0951 | sucC | 0.992 |
Rv3319 | sdhB | 0.983 |
Rv3319 | sdhB | 0.983 |
Rv1098c | fum | 0.979 |
Rv1098c | fum | 0.979 |
Rv0247c | Rv0247c | 0.944 |
Rv0247c | Rv0247c | 0.944 |
Rv0234c | gabD1 | 0.903 |
DrugBank ID | Drug Name |
---|---|
DB00730DrugBank | Thiabendazole |