Rv1304

Tuberculist information
Gene nameatpB
Protein functionProbable ATP synthase a chain AtpB (protein 6)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1460.24
Molecular mass(da)27466.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 250
	  		  	1    MTETILAAQIEVGEHHTATWLGMTVNTDTVLSTAIAGLIVIALAFYLRAKVTSTDVPGGV   60
			  	61   QLFFEAITIQMRNQVESAIGMRIAPFVLPLAVTIFVFILISNWLAVLPVQYTDKHGHTTE  120
			  	121  LLKSAAADINYVLALALFVFVCYHTAGIWRRGIVGHPIKLLKGHVTLLAPINLVEEVAKP  180
			  	181  ISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFALLTILYFS  240
			  	241  QAMELEEEHH

Known structures in the PDB
No Known structures
1 26 51 76 101 126 151 176 201 226 251 Range: 23 to 241  |  Coverage: 87% ATP-synt_A Range: 84 to 240  |  Coverage: 62% 1 Range: 81 to 240  |  Coverage: 63% 1
Number of amino acids : 250
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ATP-synt_APF0011923-241
Mtb Structural Proteome models
Model Number1
Model nameRv1304
Template1C17    MPDBCREDO
Template coverage98_265
Template Identity(%)36.0
Model coverage(%)62.4
Normalized DOPE score1.432

Structure Models from Chopin
Model Number1
Profilef.18.1.1 - 1.20.120.220
Click for model details
zscore22.9
Residue begin81
Residue end240
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1304Gene nameConfidence Score
Rv1310atpD0.999
Rv1308atpA0.999
Rv1311atpC0.999
Rv1308atpA0.999
Rv1308atpA0.999
Rv1305atpE0.999
Rv1309atpG0.999
Rv1306atpF0.999
Rv1310atpD0.999
Rv1310atpD0.999
Rv1307atpH0.993
Rv1307atpH0.993
Rv1303Rv13030.935
Rv3628ppa0.928
Rv0733adk0.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
H(+)PubChem0.9112.01588
deuteriumPubChem0.9092.01588
adenosine triphosphatePubChem0.903507.181
phosphatePubChem0.996.9872
protiumPubChem0.92.01576
adenosine monophosphatePubChem0.9347.221
deoxyadenosine triphosphatePubChem0.9491.182
hydroxyl radicalsPubChem0.917.0073
adenosine diphosphatePubChem0.9427.201