Rv1867

Tuberculist information
Gene nameRv1867
Protein functionConserved protein
Functional category(tuberculist)lipid metabolism
Gene location(kb)2115.76
Molecular mass(da)53560.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 494
	  		  	1    MPVDPRTPVLIGYGQVNHRGDIDAEKQSIEPVDLMAAAARKAADSTVLEAVDSIRVVHML   60
			  	61   SAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSLVNRACLDIQRGRAGVVLLAGAETWR  120
			  	121  TRTGLRAKGSKLEWTVQDESVPLPDMAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIA  180
			  	181  YGESIENHRKRIGELWARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNS  240
			  	241  NNMVDQGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAIRIAGA  300
			  	301  RALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLTVTGGLTFAGGPWSNY  360
			  	361  VTHSIATMAELLAANPGRRGLITANGGYLTKHSFGVYGTEPPSEFRWEDMQPAVDREPTG  420
			  	421  DGLVEWEGIGTVEAWTTPVNRDGQPEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAG  480
			  	481  VKVAVAPDGTATLR

Known structures in the PDB
No Known structures
1 50 99 148 197 246 295 344 393 442 491 Range: 291 to 375  |  Coverage: 17% Ketoacyl-synt_C Range: 8 to 476  |  Coverage: 94% 1 Range: 1 to 261  |  Coverage: 52% 1
Number of amino acids : 494
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ketoacyl-synt_CPF02801291-375
Mtb Structural Proteome models
Model Number1
Model nameRv1867
Template2HG4    APDBCREDO
Template coverage41_494
Template Identity(%)15.3
Model coverage(%)94.7
Normalized DOPE score0.723

Structure Models from Chopin
Model Number1
Profilec.95.1.1
Click for model details
zscore12.46
Residue begin1
Residue end261
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1867Gene nameConfidence Score
Rv0896gltA20.922
Rv2790cltp10.915
Rv2790cltp10.915
Rv0889ccitA0.914
Rv0131cfadE10.912
Rv0131cfadE10.912
Rv0131cfadE10.912
Rv0231fadE40.91
Rv0975cfadE130.91
Rv0975cfadE130.91
Rv0975cfadE130.91
Rv0231fadE40.91
Rv1131prpC0.91
Rv0154cfadE20.901
Rv0154cfadE20.901
Rv0154cfadE20.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
acetyl-CoAPubChem0.901809.571
3-ketohexanoyl-CoAPubChem0.9879.661
acetoacetyl-CoAPubChem0.9851.607
butyryl-CoAPubChem0.9837.624