Rv1164

Tuberculist information
Gene namenarI
Protein functionProbable respiratory nitrate reductase (gamma chain) NarI
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1293.41
Molecular mass(da)28040.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 246
	  		  	1    LAVLDLVEIFWDAAPYVVVAIAVVGTWWRYRYDKFGWTTRSSQLYESRLLSIGSPMFHFG   60
			  	61   SLLVIMGHVMGLFIPDSWTRAFGMSDHLYHLQALLLGAPAGFATLLGIGLLIYRRRIQTP  120
			  	121  VWLATTRNDKLMYLVLVCAIVAGLACTLMGATHEGDMHDYRRSVSVWFRSIWMLAPRGDL  180
			  	181  MAQATLYYQVHVLIALALFALWPFTRLVHAFSAPIAYLFRPYIVYRSREVAAKHELIGSA  240
			  	241  PRRRGW

Known structures in the PDB
No Known structures
1 25 49 73 97 121 145 169 193 217 241 Range: 5 to 229  |  Coverage: 91% Nitrate_red_gam Range: 6 to 228  |  Coverage: 90% 1 Range: 4 to 229  |  Coverage: 91% 1
Number of amino acids : 246
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Nitrate_red_gamPF026655-229
Mtb Structural Proteome models
Model Number1
Model nameRv1164
Template1Q16    CPDBCREDO
Template coverage4_224
Template Identity(%)30.0
Model coverage(%)90.2
Normalized DOPE score0.925

Structure Models from Chopin
Model Number1
Profilef.21.3.1 - 1.20.950.20
Click for model details
zscore38.88
Residue begin4
Residue end229
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1164Gene nameConfidence Score
Rv1163narJ0.999
Rv1161narG0.999
Rv1161narG0.999
Rv1161narG0.999
Rv1162narH0.999
Rv1162narH0.999
Rv0252nirB0.98
Rv0252nirB0.98
Rv0252nirB0.98
Rv0252nirB0.98
Rv0252nirB0.98
Rv1737cnarK20.973
Rv0267narU0.951
Rv0253nirD0.945
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
nitratePubChem0.94862.0049
nitrite ionPubChem0.946.0055
nitrous acidPubChem0.946.0055