Rv1163

Tuberculist information
Gene namenarJ
Protein functionProbable respiratory nitrate reductase (delta chain) NarJ
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1292.8
Molecular mass(da)21886
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 201
	  		  	1    VWQSASLLLAYPDDGLAERLHMVDALRAHQTGPAAALLGRTVAELRALAPMAAAAQYVET   60
			  	61   FDMRRRSTMYLTYWTAGDTRNRGREMLAFATAYRDAGVKPPRTEAPDYLPVVLEFAATVD  120
			  	121  PEAGRRLLTEHRVPIDVLRGALADAKSPYEYTVAAICETLPAATNQEVRRAQRLAQSGPP  180
			  	181  AEAVGLQPFTLTVPPKRAEGA

Known structures in the PDB
No Known structures
1 21 41 61 81 101 121 141 161 181 201 Range: 1 to 160  |  Coverage: 79% Nitrate_red_del Range: 3 to 161  |  Coverage: 78% 1
Number of amino acids : 201
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Nitrate_red_delPF026131-160
Mtb Structural Proteome models
Model Number1
Model nameRv1163
Template1ZE0    APDBCREDO
Template coverage6_152
Template Identity(%)20.4
Model coverage(%)78.6
Normalized DOPE score0.015

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1163Gene nameConfidence Score
Rv1164narI0.999
Rv1161narG0.999
Rv1161narG0.999
Rv1161narG0.999
Rv1162narH0.999
Rv1162narH0.999
Rv0252nirB0.977
Rv0252nirB0.977
Rv0252nirB0.977
Rv0252nirB0.977
Rv0252nirB0.977
Rv1737cnarK20.951
Rv0253nirD0.943
Rv0267narU0.921
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
nitratePubChem0.94162.0049
nitrite ionPubChem0.92846.0055
nitrous acidPubChem0.92846.0055