Rv0267

Tuberculist information
Gene namenarU
Protein functionProbable integral membrane nitrite extrusion protein NarU (nitrite facilitator)
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)321.331
Molecular mass(da)49133.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 463
	  		  	1    MALTTAPAIDYALPRQQDEGDHWIDDWRPEDPVFWETIGRPIARRNLIFSIFAEHVGFSV   60
			  	61   WMLWSIVVVQMTAAAPGHPAASGWALSASQALCLVAVPSGVGAFLRLPYTFAIPIFGGRN  120
			  	121  WTTVSAALLVIPCLLLAWAVSHPSLPFAVLVVIAATAGFGGGNFASSMANISFFYPEKDK  180
			  	181  GWALGLNAAGGNIGVAVVQKIIPPIVVAGSGVALSRAGLFFVPLAVAAAVCAFLFMNNLT  240
			  	241  EAKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYSAAFPTLLKTVFGRGDIALGWAFLG  300
			  	301  AGIGSLVRPLGGKLADRIGGARITAASFVMLAAGAAAALWSVQSVNLPVFFVSFMFLFVA  360
			  	361  TGIGNGSSYRMISRIFQVKGEVAGGDPETMVNMRRQAAGALGIISSIGAFGGFVVPLAYA  420
			  	421  WSKVHFGNIEPALHFYVAFFLALLVVTWYCYLRRTTPMGQVGV

Known structures in the PDB
No Known structures
1 47 93 139 185 231 277 323 369 415 461 Range: 47 to 416  |  Coverage: 79% MFS_1 Range: 32 to 461  |  Coverage: 92% 1 Range: to   |  Coverage: 0% 1
Number of amino acids : 463
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MFS_1PF0769047-416
Mtb Structural Proteome models
Model Number1
Model nameRv0267
Template1PW4    APDBCREDO
Template coverage16_445
Template Identity(%)13.7
Model coverage(%)92.7
Normalized DOPE score0.776

Structure Models from Chopin
Model Number1
Profilef.38.1.1
Click for model details
zscore10.52
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0267Gene nameConfidence Score
Rv1161narG0.983
Rv1161narG0.983
Rv1161narG0.983
Rv1164narI0.951
Rv1162narH0.936
Rv1162narH0.936
Rv1163narJ0.921
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions