Rv1110

Tuberculist information
Gene namelytB2
Protein functionProbable LYTB-related protein LytB2
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1236.19
Molecular mass(da)36297.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 335
	  		  	1    MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYV   60
			  	61   RHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDAT  120
			  	121  CPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDE  180
			  	181  DKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVI  240
			  	241  VVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRG  300
			  	301  VLERLAECGYDIVQPVTTANETLVFALPRELRSPR

Known structures in the PDB
No Known structures
1 34 67 100 133 166 199 232 265 298 331 Range: 28 to 308  |  Coverage: 83% LYTB
Number of amino acids : 335
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
LYTBPF0240128-308
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1110Gene nameConfidence Score
Rv2868cgcpE0.999
Rv3581cispF0.987
Rv2870cdxr0.974
Rv2870cdxr0.974
Rv2870cdxr0.974
Rv2682cdxs10.972
Rv2682cdxs10.972
Rv2682cdxs10.972
Rv3582cispD0.965
Rv1011ispE0.956
Rv1011ispE0.956
Rv1630rpsA0.946
Rv1745cidi0.942
Rv3398cidsA10.932
Rv3383cidsB0.928
Rv1086Rv10860.926
Rv2173idsA20.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
dimethylallyl diphosphatePubChem0.982246.092
isopentenyl diphosphatePubChem0.981246.092
(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphatePubChem0.944262.091
1-deoxy-D-xylulose 5-phosphatePubChem0.754214.11
mevalonatePubChem0.725148.157