Rv0619

Tuberculist information
Gene namegalTb
Protein functionProbable galactose-1-phosphate uridylyltransferase GalTb [second part]
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)712.174
Molecular mass(da)20744.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 181
	  		  	1    GDRGDPAHPHGQIYAYPYLTPRTAAMLRQARRHRKRHGDNLFASLLAREVADGSRIVVRG   60
			  	61   ELFTAFVPFAARWPVEVHIYPNRLVRNLTELNDGELDEFARIYLDVLQRFDRMYSSPLPY  120
			  	121  MSALHQFSEVQRDGYFHVELMSIRRSATKLKYLAAAESAMDAFIADVIPESVATRLRELG  180
			  	181  P

Known structures in the PDB
No Known structures
1 19 37 55 73 91 109 127 145 163 181 Range: 26 to 179  |  Coverage: 84% GalP_UDP_tr_C Range: 8 to 177  |  Coverage: 93% 1 Range: 22 to 181  |  Coverage: 87% 1
Number of amino acids : 181
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
GalP_UDP_tr_CPF0274426-179
Mtb Structural Proteome models
Model Number1
Model nameRv0619
Template1GUP    APDBCREDO
Template coverage164_336
Template Identity(%)30.0
Model coverage(%)93.4
Normalized DOPE score0.002

Structure Models from Chopin
Model Number1
Profiled.13.1.1 - 3.30.428.10
Click for model details
zscore8.68
Residue begin22
Residue end181
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0619Gene nameConfidence Score
Rv0620galK0.999
Rv0620galK0.999
Rv0620galK0.999
Rv0618galTa0.999
Rv3634cgalE10.941
Rv0993galU0.912
Rv3068cpgmA0.91
Rv3068cpgmA0.91
Rv3068cpgmA0.91
Rv3068cpgmA0.91
Rv0536galE30.907
Rv3257cpmmA0.905
Rv3257cpmmA0.905
Rv3257cpmmA0.905
Rv3257cpmmA0.905
Rv0322udgA0.902
Rv0322udgA0.902
Rv0322udgA0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
galactosePubChem0.933180.156
UDP-glucosePubChem0.931566.302
galactose-1-phosphatePubChem0.926336.316
glucose-1-phosphatePubChem0.925260.136
UDP-galactosePubChem0.922566.302
alpha-galactosePubChem0.908180.156
uridine diphosphate galactosePubChem0.906566.302
UDP-GlcPubChem0.905566.302
uridine triphosphatePubChem0.9484.141
adenosine diphosphatePubChem0.9427.201
adenosine triphosphatePubChem0.9507.181
G0053PubChem0.9260.136
deuteriumPubChem0.92.01588
protiumPubChem0.92.01576
H(+)PubChem0.92.01588
pyrophosphatePubChem0.9177.975