Tuberculist information
Gene nameubiA
Protein functionDecaprenylphosphoryl-5-phosphoribose (DPPR) synthase (decaprenyl-phosphate 5-phosphoribosyltransferase)
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)4268.92
Molecular mass(da)32654.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 302
	  		  	1    MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALGGGVRYDYVEVLSKVSMAFV   60
			  	61   VFSLAASAVYLVNDVRDVEADREHPTKRFRPIAAGVVPEWLAYTVAVVLGVTSLAGAWML  120
			  	121  TPNLALVMVVYLAMQLAYCFGLKHQAVVEICVVSSAYLIRAIAGGVATKIPLSKWFLLIM  180
			  	181  AFGSLFMVAGKRYAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFER  240
			  	241  DGYSGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRVLQLLALAWIATVGAAVA  300
			  	301  FG
			  			

Known structures in the PDB
No Known structures
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UbiAPF0104029-300
Mtb Structural Proteome models
Model Number1
Model nameRv3806c
Template1XME    APDBCREDO
Template coverage14_209
Template Identity(%)17.9
Model coverage(%)66.9
Normalized DOPE score0.834

Model Number2
Model nameRv3806c.1
Template1WPG    APDBCREDO
Template coverage751_979
Template Identity(%)12.8
Model coverage(%)58.9
Normalized DOPE score1.067

Structure Models from Chopin
Model Number1
Profilef.46.1.1
Click for model details
zscore4.2
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3806cGene nameConfidence Score
Rv3790dprE10.993
Rv3790dprE10.993
Rv3791dprE20.985
Rv3807cRv3807c0.975
Rv3808cglfT20.956
Rv3805caftB0.931
Rv3809cglf0.922
Rv3809cglf0.922
Rv2073cRv2073c0.916
Potential ligand/drug binding sites
Protein ModelPocket NumberDrug Binding Site PMIN ScorePvalue PMINPMAX ScorePvalue PMAX
Rv3806c.111mx1_THA_B_2PDBCREDO0.6610.1140.6610.001
Rv3806c.141ya4_CTX_A_1PDBCREDO0.6970.0830.6480.001
Rv3806c.142xkw_P1B_A_1478PDBCREDO0.6560.1190.6390.001
Rv3806c.111xp0_VDN_A_201PDBCREDO0.6950.0850.6390.001
Rv3806c.112w8y_NDR_B_1000PDBCREDO0.6870.0910.6340.001
Rv3806c.111fko_EFZ_A_999PDBCREDO0.6570.1180.6300.001
Rv3806c.113lp0_NVP_A_701PDBCREDO0.6530.1210.6270.001
Rv3806c.113lp1_NVP_A_701PDBCREDO0.6500.1250.6230.001
Rv3806c.142qxs_RAL_A_600PDBCREDO0.7270.0620.6210.001
Rv3806c.143gp0_NIL_A_1PDBCREDO0.6690.1070.6190.001
Rv3806c.142qxs_RAL_B_600PDBCREDO0.7240.0640.6190.001
Rv3806c.113b2r_VDN_B_1PDBCREDO0.7330.0580.6170.002
Rv3806c.111tbf_VIA_A_501PDBCREDO0.7620.0410.6130.002
Rv3806c.113nt1_NPS_B_4PDBCREDO0.6390.1360.6130.002
Rv3806c.113nt1_NPS_A_5PDBCREDO0.6380.1370.6120.002
Rv3806c.111mx1_THA_D_4PDBCREDO0.6620.1130.6110.002
Rv3806c.113b2r_VDN_A_1PDBCREDO0.7250.0630.6110.002
Rv3806c.111mx1_THA_F_6PDBCREDO0.6610.1140.6090.002
Rv3806c.111s9p_DES_B_459PDBCREDO0.6610.1140.6090.002
Rv3806c.111mx1_THA_A_1PDBCREDO0.6340.1410.6080.002
Rv3806c.111s9p_DES_C_500PDBCREDO0.6580.1170.6070.002
Rv3806c.111g50_EST_A_600PDBCREDO0.6320.1430.6070.002
Rv3806c.113n8z_FLP_B_1701PDBCREDO0.6320.1430.6070.002
Rv3806c.111dtl_BEP_A_205PDBCREDO0.6040.1750.6040.002
Rv3806c.112yja_EST_B_1550PDBCREDO0.6280.1470.6030.002
Rv3806c.113uud_EST_A_600PDBCREDO0.6270.1490.6020.002
Rv3806c.112ayl_FLP_B_2701PDBCREDO0.6000.1790.6000.002
Rv3806c.111gs4_ZK5_A_1918PDBCREDO0.7860.0300.6000.002
Rv3806c.113ols_EST_B_600PDBCREDO0.6250.1500.6000.002
Rv3806c.113uud_EST_B_600PDBCREDO0.6250.1500.6000.002
Rv3806c.111eqh_FLP_A_701PDBCREDO0.6480.1260.5960.002
Rv3806c.113ols_EST_A_600PDBCREDO0.6200.1560.5950.002
Rv3806c.111eqh_FLP_B_1701PDBCREDO0.6470.1280.5940.002
Rv3806c.111xoz_CIA_A_501PDBCREDO0.7390.0540.5940.002
Rv3806c.111cqe_FLP_A_1650PDBCREDO0.6450.1300.5930.002
Rv3806c.111cqe_FLP_B_2650PDBCREDO0.6410.1330.5890.003
Rv3806c.111ya4_CTX_C_3PDBCREDO0.6390.1360.5890.003
Rv3806c.111ya4_CTX_B_2PDBCREDO0.6380.1370.5880.003
Rv3806c.112j7y_E3O_A_1454PDBCREDO0.6890.0900.5880.003
Rv3806c.113erd_DES_A_600PDBCREDO0.7690.0380.5870.003
Rv3806c.111lwf_NVP_A_999PDBCREDO0.6120.1650.5870.003
Rv3806c.113n8y_DIF_B_585PDBCREDO0.7610.0420.5840.003
Rv3806c.112hny_NVP_A_999PDBCREDO0.6070.1700.5820.003
Rv3806c.113qip_NVP_A_561PDBCREDO0.6060.1710.5820.003
Rv3806c.113pgh_FLP_D_701PDBCREDO0.6310.1440.5800.003
Rv3806c.111dtl_BEP_A_204PDBCREDO0.6010.1780.5770.003
Rv3806c.111lwc_NVP_A_999PDBCREDO0.6010.1780.5770.003
Rv3806c.111g50_EST_C_2600PDBCREDO0.6260.1490.5760.003
Rv3806c.113oll_EST_B_600PDBCREDO0.6260.1490.5760.003
Rv3806c.113oll_EST_A_600PDBCREDO0.6250.1500.5750.003
Rv3806c.111a52_EST_A_1PDBCREDO0.6230.1530.5720.003
Rv3806c.111pcg_EST_A_1PDBCREDO0.6230.1530.5720.003
Rv3806c.113lfa_1N1_A_361PDBCREDO0.5970.1830.5720.003
Rv3806c.113adx_IMN_B_3PDBCREDO0.5960.1840.5720.003
Rv3806c.141xkk_FMM_A_91PDBCREDO0.6020.1770.5720.003
Rv3806c.112j7x_EST_A_1454PDBCREDO0.6220.1540.5710.004
Rv3806c.112hnd_NVP_A_999PDBCREDO0.5950.1850.5710.004
Rv3806c.111ere_EST_D_600PDBCREDO0.6200.1560.5700.004
Rv3806c.111s9p_DES_D_600PDBCREDO0.7720.0360.5690.004
Rv3806c.111a52_EST_B_2PDBCREDO0.6190.1570.5690.004
Rv3806c.111ere_EST_C_600PDBCREDO0.6190.1570.5690.004
Rv3806c.113hm1_J3Z_B_1PDBCREDO0.6190.1570.5690.004
Rv3806c.111ere_EST_F_600PDBCREDO0.6180.1580.5680.004
Rv3806c.112ayl_FLP_A_1701PDBCREDO0.6400.1340.5680.004
Rv3806c.111sqn_NDR_A_1001PDBCREDO0.7680.0380.5660.004
Rv3806c.112ocf_EST_A_596PDBCREDO0.6150.1610.5650.004
Rv3806c.111sqn_NDR_B_2001PDBCREDO0.7670.0390.5650.004
Rv3806c.111mx1_THA_E_5PDBCREDO0.7120.0720.5640.004
Rv3806c.113h0a_9RA_A_500PDBCREDO0.8190.0180.5630.004
Rv3806c.143ucb_017_A_201PDBCREDO0.6210.1550.5630.004
Rv3806c.143ogq_AB1_A_200PDBCREDO0.5770.2080.5630.004
Rv3806c.111qkt_EST_A_600PDBCREDO0.6110.1660.5620.004
Rv3806c.143cs9_NIL_B_600PDBCREDO0.6570.1180.5610.004
Rv3806c.113bbt_FMM_B_91PDBCREDO0.6570.1170.5610.004
Rv3806c.143cs9_NIL_A_600PDBCREDO0.6740.1020.5610.004
Rv3806c.143cs9_NIL_C_600PDBCREDO0.6210.1540.5600.004
Rv3806c.113n8z_FLP_A_701PDBCREDO0.6560.1180.5600.004
Rv3806c.111s9p_DES_A_459PDBCREDO0.7600.0420.5600.004
Rv3806c.111a27_EST_A_350PDBCREDO0.6310.1440.5600.004
Rv3806c.113pgh_FLP_C_701PDBCREDO0.6930.0860.5580.004
Rv3806c.143b0w_DGX_B_1PDBCREDO0.6890.0900.5570.004
Rv3806c.143cs9_NIL_D_600PDBCREDO0.6170.1590.5570.004
Rv3806c.143ufn_ROC_A_401PDBCREDO0.6010.1780.5560.005
Rv3806c.111fk9_EFZ_A_999PDBCREDO0.6010.1780.5550.005
Rv3806c.111lw0_NVP_A_999PDBCREDO0.5990.1800.5530.005
Rv3806c.111fkp_NVP_A_999PDBCREDO0.5750.2100.5520.005
Rv3806c.113h52_486_C_4PDBCREDO0.7210.0660.5510.005
Rv3806c.111jkh_EFZ_A_999PDBCREDO0.5740.2120.5500.005
Rv3806c.112fum_MIX_B_1539PDBCREDO0.5690.2180.5460.005
Rv3806c.113tmz_06X_A_503PDBCREDO0.5900.1910.5430.006
Rv3806c.112zva_1N1_A_513PDBCREDO0.5880.1940.5420.006
Rv3806c.143sm2_478_A_126PDBCREDO0.5390.2590.5390.006
Rv3806c.142pym_1UN_A_1001PDBCREDO0.5530.2400.5390.006
Rv3806c.142q64_1UN_B_1001PDBCREDO0.5530.2400.5390.006
Rv3806c.142qak_1UN_A_1001PDBCREDO0.5530.2400.5390.006
Rv3806c.142pyn_1UN_A_1001PDBCREDO0.5510.2420.5380.006
Rv3806c.113vkx_T3_A_301PDBCREDO0.7340.0570.5370.006
Rv3806c.142q63_1UN_A_1001PDBCREDO0.5510.2430.5370.006
Rv3806c.133ucb_017_A_201PDBCREDO0.6450.1300.5370.006
Rv3806c.133oxc_ROC_A_401PDBCREDO0.5470.2480.5350.006
Rv3806c.111udu_CIA_B_2003PDBCREDO0.5820.2010.5350.006
Rv3806c.113erd_DES_B_800PDBCREDO0.7000.0810.5340.006
Rv3806c.112h42_VIA_C_903PDBCREDO0.6990.0820.5340.006
Rv3806c.131k6c_MK1_B_902PDBCREDO0.6250.1500.5330.007
Rv3806c.143gcs_BAX_A_401PDBCREDO0.7390.0540.5330.007
Rv3806c.113pgh_FLP_B_701PDBCREDO0.6620.1130.5320.007
Rv3806c.133gp0_NIL_A_1PDBCREDO0.7610.0420.5320.007
Rv3806c.111s1u_NVP_A_999PDBCREDO0.5540.2380.5310.007
Rv3806c.142f80_017_B_301PDBCREDO0.5440.2520.5310.007
Rv3806c.113hvt_NVP_A_557PDBCREDO0.5520.2410.5300.007
Rv3806c.111mrl_DOL_A_300PDBCREDO0.5510.2420.5290.007
Rv3806c.111eqg_IBP_B_1701PDBCREDO0.6540.1200.5260.007
Rv3806c.113sxr_1N1_A_1PDBCREDO0.5710.2160.5260.007
Rv3806c.112q1v_PDN_A_248PDBCREDO0.7390.0540.5260.007
Rv3806c.111fdu_EST_C_353PDBCREDO0.5930.1880.5260.007
Rv3806c.111jlb_NVP_A_999PDBCREDO0.6240.1510.5260.007
Rv3806c.112gqg_1N1_A_501PDBCREDO0.6880.0900.5250.007
Rv3806c.143heg_BAX_A_1PDBCREDO0.7500.0480.5250.007
Rv3806c.111cqp_803_B_311PDBCREDO0.6520.1220.5250.007
Rv3806c.111mx1_THA_C_3PDBCREDO0.7110.0730.5240.008
Rv3806c.113axz_ADN_A_401PDBCREDO0.5950.1850.5240.008
Rv3806c.113tbg_RTZ_A_1PDBCREDO0.5460.2490.5240.008
Rv3806c.113clb_TMQ_B_612PDBCREDO0.6500.1240.5230.008
Rv3806c.113hbb_TMQ_C_613PDBCREDO0.5940.1860.5230.008
Rv3806c.111nhz_486_A_800PDBCREDO0.7870.0300.5230.008
Rv3806c.113sxr_1N1_B_2PDBCREDO0.5440.2520.5220.008
Rv3806c.111gwr_EST_A_600PDBCREDO0.6490.1250.5220.008
Rv3806c.111eqg_IBP_A_701PDBCREDO0.6480.1260.5210.008
Rv3806c.113hm1_J3Z_A_2PDBCREDO0.6480.1260.5210.008
Rv3806c.143bjw_SVR_B_501PDBCREDO0.5480.2470.5210.008
Rv3806c.111g50_EST_B_1600PDBCREDO0.6470.1270.5200.008
Rv3806c.113clb_TMQ_A_611PDBCREDO0.5910.1900.5200.008
Rv3806c.143oxx_DR7_A_100PDBCREDO0.5200.2870.5200.008
Rv3806c.131rl8_RIT_A_9001PDBCREDO0.6560.1190.5200.008
Rv3806c.113vri_1KX_A_301PDBCREDO0.5640.2250.5200.008
Rv3806c.111qku_EST_A_600PDBCREDO0.6460.1290.5200.008
Rv3806c.113jwq_VIA_C_901PDBCREDO0.7830.0310.5200.008
Rv3806c.111a28_STR_A_1PDBCREDO0.7050.0770.5190.008
Rv3806c.111ere_EST_A_600PDBCREDO0.6450.1300.5190.008
Rv3806c.141skx_RFP_A_1PDBCREDO0.6070.1710.5190.008
Rv3806c.111ere_EST_E_600PDBCREDO0.6440.1310.5180.008
Rv3806c.111lwe_NVP_A_999PDBCREDO0.6150.1610.5180.008
Rv3806c.111pcg_EST_B_2PDBCREDO0.6440.1310.5180.008
Rv3806c.111qku_EST_B_600PDBCREDO0.6440.1310.5180.008
Rv3806c.111qku_EST_C_600PDBCREDO0.6440.1310.5180.008
Rv3806c.142aqu_DR7_B_300PDBCREDO0.5170.2920.5170.008
Rv3806c.133cyx_ROC_A_201PDBCREDO0.5660.2230.5170.008
Rv3806c.111ere_EST_B_600PDBCREDO0.6430.1320.5170.008
Rv3806c.131t7i_017_A_200PDBCREDO0.6060.1720.5170.008
Rv3806c.143bjw_SVR_E_503PDBCREDO0.5870.1940.5160.009
Rv3806c.143bjw_SVR_F_502PDBCREDO0.5430.2540.5160.009
Rv3806c.133d1x_ROC_A_201PDBCREDO0.5270.2770.5160.009
Rv3806c.114cox_IMN_A_701PDBCREDO0.5610.2290.5150.009
Rv3806c.114cox_IMN_B_701PDBCREDO0.5610.2290.5150.009
Rv3806c.141t46_STI_A_3PDBCREDO0.5710.2150.5150.009
Rv3806c.141sdt_MK1_B_902PDBCREDO0.5550.2370.5150.009
Rv3806c.143bjw_SVR_H_504PDBCREDO0.5410.2560.5150.009
Rv3806c.113ls4_TCI_H_220PDBCREDO0.5580.2330.5150.009
Rv3806c.111gwr_EST_B_600PDBCREDO0.6400.1350.5140.009
Rv3806c.114cox_IMN_C_701PDBCREDO0.5600.2310.5140.009
Rv3806c.142avv_MK1_A_901PDBCREDO0.5810.2030.5140.009
Rv3806c.111cqp_803_A_311PDBCREDO0.6380.1360.5140.009
Rv3806c.143ndt_ROC_D_100PDBCREDO0.5660.2220.5130.009
Rv3806c.111pxx_DIF_A_701PDBCREDO0.5580.2330.5130.009
Rv3806c.111udt_VIA_A_1000PDBCREDO0.6080.1690.5120.009
Rv3806c.111vrt_NVP_A_999PDBCREDO0.6080.1690.5120.009
Rv3806c.111ya3_STR_C_3001PDBCREDO0.6460.1280.5120.009
Rv3806c.111pxx_DIF_B_1701PDBCREDO0.5560.2360.5110.009
Rv3806c.111pxx_DIF_C_2701PDBCREDO0.5560.2360.5110.009
Rv3806c.111s1x_NVP_A_999PDBCREDO0.6070.1710.5110.009
Rv3806c.132pym_1UN_A_1001PDBCREDO0.6600.1150.5110.009
Rv3806c.142nnk_ROC_A_401PDBCREDO0.5630.2260.5110.009
Rv3806c.111fds_EST_A_350PDBCREDO0.5550.2370.5100.009
Rv3806c.111pxx_DIF_D_3701PDBCREDO0.5550.2370.5100.009
Rv3806c.143oxx_DR7_C_100PDBCREDO0.5360.2640.5100.009
Rv3806c.111jlf_NVP_A_999PDBCREDO0.6050.1730.5090.009
Rv3806c.113ads_IMN_B_3PDBCREDO0.5540.2380.5090.009
Rv3806c.113pgh_FLP_A_701PDBCREDO0.6330.1420.5090.009
Rv3806c.113kw2_ADN_B_300PDBCREDO0.5520.2410.5090.009
Rv3806c.131xkk_FMM_A_91PDBCREDO0.7090.0740.5090.010
Rv3806c.133tl9_ROC_A_401PDBCREDO0.5200.2880.5090.010
Rv3806c.132pyn_1UN_A_1001PDBCREDO0.6570.1180.5080.010
Rv3806c.141y0x_T44_X_500PDBCREDO0.7490.0490.5080.010
Rv3806c.111ya3_STR_A_1001PDBCREDO0.7140.0700.5080.010
Rv3806c.132q64_1UN_B_1001PDBCREDO0.6560.1180.5080.010
Rv3806c.132qak_1UN_A_1001PDBCREDO0.6560.1180.5080.010
Rv3806c.142r5p_MK1_D_902PDBCREDO0.5340.2660.5080.010
Rv3806c.111qkn_RAL_A_600PDBCREDO0.8150.0190.5070.010
Rv3806c.142r5p_MK1_B_902PDBCREDO0.5330.2680.5070.010
Rv3806c.132q63_1UN_A_1001PDBCREDO0.6540.1210.5060.010
Rv3806c.112jj8_AZZ_A_1211PDBCREDO0.6590.1160.5060.010
Rv3806c.143k4v_ROC_D_201PDBCREDO0.5850.1980.5060.010
Rv3806c.142avo_MK1_B_902PDBCREDO0.5180.2900.5060.010
Rv3806c.141hsh_MK1_A_401PDBCREDO0.5750.2100.5050.010
Rv3806c.141hxw_RIT_B_301PDBCREDO0.5320.2700.5050.010
Rv3806c.111uho_VDN_A_1000PDBCREDO0.5270.2780.5050.010
Rv3806c.113ln1_CEL_D_682PDBCREDO0.7350.0570.5050.010
Rv3806c.112cbr_A80_A_201PDBCREDO0.6140.1630.5050.010
Rv3806c.112prg_BRL_B_2PDBCREDO0.6850.0930.5040.010
Rv3806c.111z9h_IMN_B_381PDBCREDO0.5490.2460.5040.010
Rv3806c.142fxe_DR7_A_102PDBCREDO0.5300.2720.5040.010
Rv3806c.143eky_DR7_A_100PDBCREDO0.5300.2720.5040.010
Rv3806c.111ot7_IU5_B_1002PDBCREDO0.5680.2190.5040.010
Rv3806c.111z9h_IMN_C_379PDBCREDO0.5480.2470.5030.010
Rv3806c.111z9h_IMN_D_476PDBCREDO0.5480.2470.5030.010
Rv3806c.141hxb_ROC_A_100PDBCREDO0.5160.2930.5030.010
Rv3806c.143em4_DR7_V_100PDBCREDO0.5290.2740.5030.010
Rv3806c.132nmy_ROC_A_401PDBCREDO0.5370.2620.5030.010
Rv3806c.111z9h_IMN_A_379PDBCREDO0.5470.2490.5030.010
Rv3806c.111fm6_BRL_D_503PDBCREDO0.6820.0950.5030.011
Rv3806c.143d1y_ROC_A_201PDBCREDO0.5280.2760.5020.011
Rv3806c.112h42_VIA_A_901PDBCREDO0.7290.0600.5010.011
Rv3806c.143bvb_017_B_401PDBCREDO0.5390.2590.5010.011
Rv3806c.141opj_STI_B_4PDBCREDO0.6020.1770.5010.011
Rv3806c.113k54_1N1_A_1PDBCREDO0.6320.1430.5000.011
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions