Rv3805c

Tuberculist information
Gene nameaftB
Protein functionPossible arabinofuranosyltransferase AftB
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)4266.95
Molecular mass(da)68709.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 627
	  		  	1    MVRVSLWLSVTAVAVLFGWGSWQRRWIADDGLIVLRTVRNLLAGNGPVFNQGERVEANTS   60
			  	61   TAWTYLLYVGGWVGGPMRLEYVALALAMVLSLLGMVLLMLGTGRLYAPSLRGRRAIMLPA  120
			  	121  GALVYIAVPPARDFATSGLESGLVLAYLGLLWWMMVCWSQPLRARPDSQMFLGALAFVAG  180
			  	181  CSVLVRPEFALIGGLALIMMLIAARTWRRRVLIVLAGGFLPVAYQIFRMGYYGLLVPSTA  240
			  	241  LAKDAAGDKWSQGMIYVSNFNRPYALWVPLVLSVPLGLLLMTARRRPSFLRPVLAPDYGR  300
			  	301  VARAVQSPPAVVAFIVGSGVLQALYWIRQGGDFMHGRVLLAPLFCLLAPVGVIPILLPDG  360
			  	361  KDFSRETGRWLVGALSGLWLGIAGWSLWAANSPGMGDDATRVTYSGIVDERRFYAQATGH  420
			  	421  AHPLTAADYLDYPRMAAVLTALNNTPEGALLLPSGNYNQWDLVPMIRPSSGTAPGGKPAP  480
			  	481  KPQHAVFFTNMGMLGMNVGLDVRVIDQIGLVNPLAAHTERLKHARIGHDKNLFPDWVIAD  540
			  	541  GPWVKWYPGIPGYIDQQWVTQAEAALQCPATRAVLNSVRAPITLHRFLSNVLHSYEFTRY  600
			  	601  RIDRVPRYELVRCGLDVPDGPGPPPRE

Known structures in the PDB
No Known structures
1 63 125 187 249 311 373 435 497 559 621 Range: 27 to 522  |  Coverage: 78% 1
Number of amino acids : 627
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Domain assignments not available for this query
Mtb Structural Proteome models
Model Number1
Model nameRv3805c
Template1XME    APDBCREDO
Template coverage14_509
Template Identity(%)9.5
Model coverage(%)78.9
Normalized DOPE score0.369

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3805cGene nameConfidence Score
Rv3806cubiA0.931
Rv3807cRv3807c0.93
Rv3808cglfT20.92
Rv3809cglf0.92
Rv3809cglf0.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions