Rv3252c

Tuberculist information
Gene namealkB
Protein functionProbable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauric acid omega-hydroxylase) (omega-hydroxylase) (fatty acid omega-hydroxylase) (alkane hydroxylase-rubredoxin)
Functional category(tuberculist)lipid metabolism
Gene location(kb)3630.74
Molecular mass(da)47014.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 416
	  		  	1    MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGMNQLGWHAAAQV   60
			  	61   PLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDKYYRYCTYIYIPFQYLSVVLGA  120
			  	121  YLFTAANLSWLGFDGALSWAGKLGVALSVGVLGGVGINTAHEMGHKKDSLERWLSKITLA  180
			  	181  QTCYGHFYIEHNRGHHVRVSTPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRL  240
			  	241  GVSPWNPMTYLRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLEH  300
			  	301  YGLLRQKSANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANPTRRYQTLRSMAGAP  360
			  	361  NLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDITRVNLHPRVREKALARYGASA

Known structures in the PDB
No Known structures
1 42 83 124 165 206 247 288 329 370 411 Range: 137 to 370  |  Coverage: 56% FA_desaturase
Number of amino acids : 416
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
FA_desaturasePF00487137-370
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3252cGene nameConfidence Score
Rv3251crubA0.994
Rv3250crubB0.993
Rv0147Rv01470.911
Rv0458Rv04580.911
Rv2858caldC0.91
Rv0768aldA0.91
Rv1862adhA0.905
Rv1862adhA0.905
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
n-octanePubChem0.958114.229
octanolPubChem0.936130.228
molecular oxygenPubChem0.931.9988
dihydronicotinamide formycin dinucleotidePubChem0.9665.441
octanalPubChem0.9128.212
reduced nicotinamide adenine dinucleotidePubChem0.9665.441
hydroxyl radicalsPubChem0.917.0073
NAD+PubChem0.9663.425