Rv3056

Tuberculist information
Gene namedinP
Protein functionPossible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))
Functional category(tuberculist)information pathways
Gene location(kb)3416.71
Molecular mass(da)37562.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 346
	  		  	1    MPTAAPRWILHVDLDQFLASVELLRHPELAGLPVIVGGNGDPTEPRKVVTCASYEARAYG   60
			  	61   VRAGMPLRTAARRCPEATFLPSNPAAYNAASEEVVALLRDLGYPVEVWGWDEAYLAVAPG  120
			  	121  TPDDPIEVAEEIRKVILSQTGLSCSIGISDNKQRAKIATGLAKPAGIYQLTDANWMAIMG  180
			  	181  DRTVEALWGVGPKTTKRLAKLGINTVYQLAHTDSGLLMSTFGPRTALWLLLAKGGGDTEV  240
			  	241  SAQAWVPRSRSHAVTFPRDLTCRSEMESAVTELAQRTLNEVVASSRTVTRVAVTVRTATF  300
			  	301  YTRTKIRKLQAPSTDPDVITAAARHVLDLFELDRPVRLLGVRLELA

Known structures in the PDB
No Known structures
1 35 69 103 137 171 205 239 273 307 341 Range: 12 to 160  |  Coverage: 42% IMS Range: 216 to 340  |  Coverage: 35% IMS_C Range: 8 to 342  |  Coverage: 96% 1 Range: 5 to 346  |  Coverage: 98% 1 Range: 12 to 160  |  Coverage: 42% 2 Range: 1 to 246  |  Coverage: 70% 3 Range: 247 to 346  |  Coverage: 28% 4
Number of amino acids : 346
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
IMSPF0081712-160
IMS_CPF11799216-340
Mtb Structural Proteome models
Model Number1
Model nameRv3056
Template1JX4    APDBCREDO
Template coverage2_336
Template Identity(%)27.8
Model coverage(%)96.5
Normalized DOPE score-0.24

Structure Models from Chopin
Model Number1
Profiled.240.1.1, e.8.1.7 - 1.10.150.20, 3.30.1490.100, 3.30.70.270
Click for model details
zscore59.69
Residue begin5
Residue end346
Model Number2
Profilee.8.1.7
Click for model details
zscore47.85
Residue begin12
Residue end160
Model Number3
Profilee.8.1.7
Click for model details
zscore38.33
Residue begin1
Residue end246
Model Number4
Profiled.240.1.1 - 3.30.1490.100
Click for model details
zscore20.32
Residue begin247
Residue end346
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3056Gene nameConfidence Score
Rv2720lexA0.988
Rv2720lexA0.988
Rv1696recN0.957
Rv3370cdnaE20.95
Rv3370cdnaE20.95
Rv3370cdnaE20.95
Rv3370cdnaE20.95
Rv1537dinX0.929
Rv1537dinX0.929
Rv1537dinX0.929
Rv1638uvrA0.92
Rv1633uvrB0.91
Rv1633uvrB0.91
Rv1633uvrB0.91
Rv1633uvrB0.91
Rv0002dnaN0.903
Rv0002dnaN0.903
Rv0002dnaN0.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
calciumPubChem0.70440.078
2',3'-dideoxyguanosine 5'-triphosphatePubChem0.7491.182
ddGTPPubChem0.7491.182