Rv2398c

Tuberculist information
Gene namecysW
Protein functionProbable sulfate-transport integral membrane protein ABC transporter CysW
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2694.98
Molecular mass(da)29288.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 272
	  		  	1    MTSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAWISTPAAISALNLSLL   60
			  	61   VVAIVVPLNVIFGVTTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGAL  120
			  	121  GFVEQDLGFKIIFGLPGIVLGSMFVTCPFVVREVEPVLHELGTDQEQAAATLGSGWWQTF  180
			  	181  WRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRGAEYGA  240
			  	241  YALSTLLMAVSVVVLIVQMVLDARRARAVSEG

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 69 to 267  |  Coverage: 72% BPD_transp_1 Range: 33 to 267  |  Coverage: 86% 1 Range: to   |  Coverage: 0% 1
Number of amino acids : 272
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
BPD_transp_1PF0052869-267
Mtb Structural Proteome models
Model Number1
Model nameRv2398c
Template4DCG    APDBCREDO
Template coverage4_223
Template Identity(%)7.9
Model coverage(%)86.0
Normalized DOPE score1.21

Structure Models from Chopin
Model Number1
Profilef.58.1.1 - 1.10.3720.10
Click for model details
zscore19.87
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2398cGene nameConfidence Score
Rv2397ccysA10.999
Rv2397ccysA10.999
Rv2400csubI0.999
Rv2399ccysT0.997
Rv1286cysN0.995
Rv1286cysN0.995
Rv1286cysN0.995
Rv1285cysD0.99
Rv1857modA0.908
Rv2392cysH0.906
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
sulfatePubChem0.95596.0626
phosphatePubChem0.92196.9872
adenosine triphosphatePubChem0.9507.181
adenosine diphosphatePubChem0.9427.201
hydroxyl radicalsPubChem0.917.0073