Rv1857

Tuberculist information
Gene namemodA
Protein functionProbable molybdate-binding lipoprotein ModA
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2104.99
Molecular mass(da)26544.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 261
	  		  	1    VRWIGLSTGLVSAMLVAGLVACGSNSPASSPAGPTQGARSIVVFAAASLQSAFTQIGEQF   60
			  	61   KAGNPGVNVNFAFAGSSELATQLTQGATADVFASADTAQMDSVAKAGLLAGHPTNFATNT  120
			  	121  MVIVAAAGNPKKIRSFADLTRPGLNVVVCQPSVPCGSATRRIEDATGIHLNPVSEELSVT  180
			  	181  DVLNKVITGQADAGLVYVSDALSVATKVTCVRFPEAAGVVNVYAIAVLKRTSQPALARQF  240
			  	241  VAMVTAAAGRRILDQSGFAKP

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 41 to 259  |  Coverage: 83% SBP_bac_11 Range: 39 to 258  |  Coverage: 83% 1
Number of amino acids : 261
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
SBP_bac_11PF1353141-259
Mtb Structural Proteome models
Model Number1
Model nameRv1857
Template1AMF    APDBCREDO
Template coverage3_230
Template Identity(%)29.5
Model coverage(%)83.9
Normalized DOPE score-0.939

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1857Gene nameConfidence Score
Rv1858modB0.999
Rv1859modC0.993
Rv1859modC0.993
Rv0438cmoeA20.919
Rv0438cmoeA20.919
Rv0438cmoeA20.919
Rv2398ccysW0.908
Rv0869cmoaA20.901
Rv0869cmoaA20.901
Rv0869cmoaA20.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
molybdatePubChem0.992159.938
phosphatePubChem0.90296.9872
adenosine triphosphatePubChem0.9507.181
adenosine diphosphatePubChem0.9427.201
hydroxyl radicalsPubChem0.917.0073
sulfatePubChem0.7596.0626
tungstatePubChem0.712249.853