Rv2400c

Tuberculist information
Gene namesubI
Protein functionProbable sulfate-binding lipoprotein SubI
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2696.64
Molecular mass(da)37418.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 356
	  		  	1    MLSLTLSEASCIASASRWRHIIPAGVVCALIAGIGVGCHGGPSDVVGRAGPDRAHTSITL   60
			  	61   VAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQSRGVADGKPADLVNFSVEPDIA  120
			  	121  RLVKAGKVDKDWDADATKGIPFGSVVTFVVRAGNPKNIRDWDDLLRPGIEVITPSPLSSG  180
			  	181  SAKWNLLAPYAAKSDGGRNNQAGIDFVNTLVNEHVKLRPGSGREATDVFVQGSGDVLISY  240
			  	241  ENEAIATERAGKPVQHVTPPQTFKIENPLAVVATSTHLGAATAFRNFQYTVQAQKLWAQA  300
			  	301  GFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLFDKATGSITKIYLRATG

Known structures in the PDB
No Known structures
1 36 71 106 141 176 211 246 281 316 351 Range: 58 to 303  |  Coverage: 68% SBP_bac_11 Range: 54 to 352  |  Coverage: 83% 1
Number of amino acids : 356
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
SBP_bac_11PF1353158-303
Mtb Structural Proteome models
Model Number1
Model nameRv2400c
Template1SBP    APDBCREDO
Template coverage1_309
Template Identity(%)32.4
Model coverage(%)83.7
Normalized DOPE score-1.076

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2400cGene nameConfidence Score
Rv2398ccysW0.999
Rv2399ccysT0.999
Rv2397ccysA10.999
Rv2397ccysA10.999
Rv1286cysN0.998
Rv1286cysN0.998
Rv1286cysN0.998
Rv1285cysD0.994
Rv2392cysH0.965
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
sulfatePubChem0.97796.0626
adenosine triphosphatePubChem0.9507.181
phosphatePubChem0.996.9872
adenosine diphosphatePubChem0.9427.201
hydroxyl radicalsPubChem0.917.0073