Rv2377c

Tuberculist information
Gene namembtH
Protein functionPutative conserved protein MbtH
Functional category(tuberculist)lipid metabolism
Gene location(kb)2656.22
Molecular mass(da)8049.86
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 71
	  		  	1    VSTNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASRAACLDYVEKNWTDLR   60
			  	61   PKSLRDAMVED

Known structures in the PDB
PDB ID2KHR
Total residue count74
Number of chains1
MethodNMR
ResolutionN/A
1 8 15 22 29 36 43 50 57 64 71 Range: 1 to 54  |  Coverage: 74% MbtH Range: 9 to 69  |  Coverage: 84% 1
Number of amino acids : 71
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MbtHPF036211-54
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profiled.100.2.1 - 3.90.820.10
Click for model details
zscore13.57
Residue begin9
Residue end69
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2377cGene nameConfidence Score
Rv2380cmbtE0.998
Rv2380cmbtE0.998
Rv2380cmbtE0.998
Rv2380cmbtE0.998
Rv2380cmbtE0.998
Rv2379cmbtF0.996
Rv2379cmbtF0.996
Rv2379cmbtF0.996
Rv2379cmbtF0.996
Rv2378cmbtG0.962
Rv2383cmbtB0.939
Rv2383cmbtB0.939
Rv2383cmbtB0.939
Rv2383cmbtB0.939
Rv2383cmbtB0.939
Rv2383cmbtB0.939
Rv3215entC0.922
Rv0101nrp0.901
Rv0101nrp0.901
Rv0101nrp0.901
Rv0101nrp0.901
Rv0101nrp0.901
Rv0101nrp0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
mycobactinPubChem0.791591.61