Rv0174

Tuberculist information
Gene namemce1F
Protein functionMce-family protein Mce1F
Functional category(tuberculist)virulence,detoxification and adaptaion
Gene location(kb)205.231
Molecular mass(da)54005.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 515
	  		  	1    VLTRFIRRQLILFAIVSVVAIVVLGWYYLRIPSLVGIGQYTLKADLPASGGLYPTANVTY   60
			  	61   RGITIGKVTAVEPTDQGARVTMSIASNYKIPVDASANVHSVSAVGEQYIDLVSTGAPGKY  120
			  	121  FSSGQTITKGTVPSEIGPALDNSNRGLAALPTEKIGLLLDETAQAVGGLGPALQRLVDST  180
			  	181  QAIVGDFKTNIGDVNDIIENSGPILDSQVNTGDQIERWARKLNNLAAQTATRDQNVRSIL  240
			  	241  SQAAPTADEVNAVFSGVRDSLPQTLANLEVVFDMLKRYHAGVEQLLVFLPQGAAIAQTVL  300
			  	301  TPTPGAAQLPLAPAINYPPPCLTGFLPASEWRSPADTSPRPLPSGTYCKIPQDAQLQVRG  360
			  	361  ARNIPCVDVLGKRAATPKECRSKDPYVPLGTNPWFGDPNQILTCPAPGARCDQPVKPGLV  420
			  	421  IPAPSINTGLNPAPADQVQGTPPPVSDPLQRPGSGTVQCNGQQPNPCVYTPTSGPSAVYS  480
			  	481  PASGELVGPDGVKYAVANSSTTGDDGWKEMLAPAS

Known structures in the PDB
No Known structures
1 52 103 154 205 256 307 358 409 460 511 Range: 38 to 114  |  Coverage: 14% MCE Range: 148 to 263  |  Coverage: 22% 1
Number of amino acids : 515
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MCEPF0247038-114
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profilea.24.26.1 - 1.20.120.440
Click for model details
zscore5.05
Residue begin148
Residue end263
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0174Gene nameConfidence Score
Rv0167yrbE1A0.98
Rv0168yrbE1B0.98
Rv0171mce1C0.965
Rv0170mce1B0.955
Rv0170mce1B0.955
Rv0169mce1A0.946
Rv0169mce1A0.946
Rv0175Rv01750.942
Rv0178Rv01780.923
Rv0173lprK0.916
Rv0172mce1D0.914
Rv0177Rv01770.908
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions