Rv0172

Tuberculist information
Gene namemce1D
Protein functionMce-family protein Mce1D
Functional category(tuberculist)virulence,detoxification and adaptaion
Gene location(kb)202.476
Molecular mass(da)56498.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 530
	  		  	1    LSTIFDIRNLRLPQLSRASVVIGSLVVVLALAAGIVGVRLYQKLTNNTVVAYFTQANALY   60
			  	61   VGDKVQIMGLPVGSIDKIEPAGDKMKVTFHYQNKYKVPANASAVILNPTLVASRNIQLEP  120
			  	121  PYRGGPVLADNAVIPVERTQVPTEWDELRDSVSHIIDELGPTPEQPKGPFGEVIEAFADG  180
			  	181  LAGKGKQINTTLNSLSQALNALNEGRGDFFAVVRSLALFVNALHQDDQQFVALNKNLAEF  240
			  	241  TDRLTHSDADLSNAIQQFDSLLAVARPFFAKNREVLTHDVNNLATVTTTLLQPDPLDGLE  300
			  	301  TVLHIFPTLAANINQLYHPTHGGVVSLSAFTNFANPMEFICSSIQAGSRLGYQESAELCA  360
			  	361  QYLAPVLDAIKFNYFPFGLNVASTASTLPKEIAYSEPRLQPPNGYKDTTVPGIWVPDTPL  420
			  	421  SHRNTQPGWVVAPGMQGVQVGPITQGLLTPESLAELMGGPDIAPPSSGLQTPPGPPNAYD  480
			  	481  EYPVLPPIGLQAPQVPIPPPPPGPDVIPGPVPPTPAPVGAPLPAEAGGGQ

Known structures in the PDB
No Known structures
1 54 107 160 213 266 319 372 425 478 531 Range: 45 to 121  |  Coverage: 14% MCE Range: 125 to 273  |  Coverage: 27% 1 Range: 86 to 288  |  Coverage: 38% 2
Number of amino acids : 530
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MCEPF0247045-121
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profilea.29.9.1 - 1.20.1440.20
Click for model details
zscore9.78
Residue begin125
Residue end273
Model Number2
Profilea.238.1.2 - 1.20.1270.60
Click for model details
zscore8.81
Residue begin86
Residue end288
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0172Gene nameConfidence Score
Rv0171mce1C0.94
Rv0170mce1B0.934
Rv0170mce1B0.934
Rv0168yrbE1B0.928
Rv0173lprK0.922
Rv0169mce1A0.919
Rv0169mce1A0.919
Rv0174mce1F0.914
Rv0175Rv01750.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions