Rv0173

Tuberculist information
Gene namelprK
Protein functionPossible Mce-family lipoprotein LprK (Mce-family lipoprotein Mce1E)
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)204.065
Molecular mass(da)42239.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 390
	  		  	1    MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPGGPGTGPGSYTIYVQMPD   60
			  	61   TLAINGNSRVMVADVWVGSIRAIKLKNWVATLTLSLKKDVTLPKNATAKIGQTSLLGSQH  120
			  	121  VELAAPPDPSPVPLKDGDTIPLKRSSAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAI  180
			  	181  VTGRADQIRAFLGKLDTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLTDLPPL  240
			  	241  IKHFADKQELLINASDAVGRLSQSADQYLSAARGDLHQDLQALQCPLKELRRAAPYLVGA  300
			  	301  LKLILTQPFDVDTVPQLVRGDYMNLSLTLDLTYSAIDNAFLTGTGFSGALRALEQSFGRD  360
			  	361  PETMIPDIRYTPNPNDAPGGPLVERGNRQC

Known structures in the PDB
No Known structures
1 40 79 118 157 196 235 274 313 352 391 Range: 50 to 126  |  Coverage: 19% MCE Range: 208 to 300  |  Coverage: 23% 1 Range: 114 to 307  |  Coverage: 49% 2
Number of amino acids : 390
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MCEPF0247050-126
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profilea.24.11.1
Click for model details
zscore8.53
Residue begin208
Residue end300
Model Number2
Profilea.24.23.1
Click for model details
zscore8.25
Residue begin114
Residue end307
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0173Gene nameConfidence Score
Rv0169mce1A0.923
Rv0169mce1A0.923
Rv0172mce1D0.922
Rv0170mce1B0.92
Rv0170mce1B0.92
Rv0174mce1F0.916
Rv0178Rv01780.916
Rv0171mce1C0.908
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions